Comparing Dronedarone vs Propafenone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Dronedarone	Propafenone	Enter another drug to compare

Dronedarone

Propafenone

Prescription only

Prescribed for Atrial Fibrillation, Atrial Flutter. Dronedarone may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Atrial Fibrillation, Atrial Flutter, Ventricular Tachycardia, Wolff-Parkinson-White Syndrome. Propafenone may also be used for purposes not listed in this medication guide.

More about Dronedarone

More about Propafenone

Ratings & Reviews

Dronedarone has an average rating of 6.2 out of 10 from a total of 53 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 26% reported a negative effect.

Propafenone has an average rating of 8.0 out of 10 from a total of 71 ratings on Drugs.com. 72% of reviewers reported a positive effect, while 11% reported a negative effect.

View all 53 reviews

View all 71 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Diarrhea (11.3%)
Upset stomach (7.5%)
Nausea (5.7%)

View all Dronedarone side effects

Dizziness (9.9%)
Metallic taste (8.5%)
Shortness of breath (7.0%)
Constipation (5.6%)
Fatigue (5.6%)
Tiredness (5.6%)
Anxiety (4.2%)

View all Propafenone side effects

Drug Class

Group III antiarrhythmics

Group I antiarrhythmics

Generic Availability

N/A

Lower cost generic

Pricing and Coupons * Prices are without insurance

We could not find an exact match for this medicine. Try searching the Price Guide directly.

Quantity	60 capsule, extended release
Strength	225 mg
Per unit^*	$0.85 - $2.35
Cost^*	$51.16 - $141.18

View all Propafenone prices

Get free Discount Card

Dosage Forms

N/A

Oral capsule, extended release
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

19 hours

17 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category X Not for use in pregnancy

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 711 drugs are known to interact with Dronedarone:

331 major drug interactions (1056 brand and generic names)
359 moderate drug interactions (1603 brand and generic names)
21 minor drug interactions (142 brand and generic names)

A total of 428 drugs are known to interact with Propafenone:

83 major drug interactions (253 brand and generic names)
326 moderate drug interactions (1279 brand and generic names)
19 minor drug interactions (47 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Do not consume grapefruit or grapefruit juice during treatment with dronedarone unless directed... View more

Consumption of grapefruit, grapefruit juice, and supplements that contain grapefruit should be... View more

Disease Interactions

First Approval Date

July 01, 2009

November 27, 1989

WADA Class View classifications

N/A

More Information

Patient Resources

Dronedarone uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Dronedarone vs Propafenone

See also:

Xarelto

Cardizem

Botox

Lanoxin

Multaq

Digitek

Propafenone

Sotalol

Flecainide

Rivaroxaban

Further information

Comparing Dronedarone vs Propafenone

See also:

Further information

Compare Drugs