Comparing Denosumab vs Zometa
| Denosumab | Zometa (zoledronic acid) |
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|---|
| Denosumab | Zometa (zoledronic acid) |
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|---|---|---|
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Prescription only
Denosumab is an injection that can be self-administered once every six months for the treatment of osteoporosis. It has been associated with an increased risk of fractures on discontinuation... View more |
Prescription only
Zometa is only available as an injection for administration by a healthcare provider and is indicated for the treatment of hypercalcemia associated with cancer, osteolytic bone lesions of multiple... View more |
Related suggestions Osteoporosis
Osteolytic Bone Metastases of Solid Tumors
Hypercalcemia of Malignancy
Osteolytic Bone Lesions of Multiple Myeloma
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| More about Denosumab | More about Zometa (zoledronic acid) | |
| Ratings & Reviews | ||
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Denosumab has an average rating of 3.0 out of 10 from a total of 396 ratings on Drugs.com. 17% of reviewers reported a positive effect, while 74% reported a negative effect. |
Zometa has an average rating of 4.8 out of 10 from a total of 44 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 50% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||
View all Denosumab side effects |
View all Zometa side effects |
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| Drug Class | ||
| Generic Availability | ||
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N/A |
Lower cost generic approved | |
| Pricing and Coupons * Prices are without insurance | ||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||
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N/A |
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| Brand Names | ||
| Bomyntra, Conexxence, Jubbonti, Osenvelt, Ospomyv, Prolia, Stoboclo, Wyost, Xbryk, Xgeva View more | Other zoledronic acid brands include: Aclasta, Reclast | |
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||
|
609.6 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | ||
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A total of 307 drugs are known to interact with Denosumab:
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A total of 123 drugs are known to interact with Zometa:
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| Alcohol/Food/Lifestyle Interactions | ||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||
| First Approval Date | ||
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N/A |
February 22, 2002 |
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| WADA Class View classifications | ||
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N/A |
N/A |
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| More Information | ||
| Patient Resources | ||
| Professional Resources | ||
| Related Treatment Guide | ||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Prolia
Prolia (denosumab) is an injection that is administered subcutaneously (under the skin) once every ...
Fosamax
Fosamax (alendronate) is used to treat or prevent postmenopausal osteoporosis and steroid-induced ...
Evenity
Evenity (romosozumab) injection is used to treat osteoporosis in postmenopausal women to reduce the ...
Decadron
Decadron is used for addison's disease, adrenal insufficiency, adrenocortical insufficiency ...
Premarin
Premarin is used to treat symptoms of menopause such as hot flashes, and vaginal dryness. Learn ...
Reclast
Reclast (zoledronic acid) is used to treat osteoporosis in women after menopause and also to treat ...
Dexamethasone Intensol
Dexamethasone Intensol is used for addison's disease, adrenal insufficiency, adrenocortical ...
Zometa
Zometa is used to treat high blood levels of calcium caused by cancer and multiple myeloma. Learn ...
Deltasone
Deltasone is used for acute lymphocytic leukemia, adrenocortical insufficiency, allergic reactions ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.