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Sofosbuvir and Diarrhea: What Users Say

Brand names: Sovaldi

Diarrhea: mentioned by 3 users (5.9%)

Based on user experiences from 51 Sofosbuvir reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 21.6%
nausea 11.8%
headaches 7.8%
itching 7.8%
depression 5.9%
diarrhea 5.9%
insomnia 5.9%
irritability 5.9%
tiredness 5.9%
upset stomach 5.9%

Reviews for Sofosbuvir

  • Zig...
  • Taken for 6 months to 1 year
  • February 14, 2017

For Hepatitis C "I did Harvoni for 12 weeks, and viral load was up 2 weeks after I completed. Harvoni made me very sick. Fatigue, diarrhea, it was kind of awful... and it failed me. I am 1a type. I also have cirrhosis F4. Next, I did Sovaldi/Olysio for 24 weeks. This time, the only side effect was fatigue, but not as bad as Harvoni. The good news is I am SVR 12 weeks post-tx, although my liver function numbers have begun to rise slightly after being normal during treatment for the first time in 30 years. But here's the real problem. I am more fatigued now than during treatment. It's been 5 months, and it's not getting any better. I get up early, exercise, have a healthy breakfast, and I'm ready to get back into bed. It really sucks. Anyone else experiencing this?"

8 / 10
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  • Mar...
  • July 2, 2015

For Hepatitis C "Have only been on Sovaldi (and Ribavirin) for three days now, so only have side effects to report on so far. Sovaldi seems to be causing the following: shortness of breath, acid reflux, diarrhea, and a horrible itchiness around my mouth and lips. All but the itchiness are tolerable-the itchiness is preventing me from eating or drinking much liquid, and I hate it. But I remain hopeful that this combo will cure the Hep C I have had for about 43 years now!"

5 / 10
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14 Report
  • tri...
  • December 14, 2015

For Hepatitis C "I started my hepatitis treatments on Nov 15th of this year. I have had some bad side effects: diarrhea, nauseous a lot, muscle aches, and headaches. I just found out that the insurance company only paid for the first month of treatments. I don't know what's going to happen now because I no longer have insurance. But I would rather go through the side effects than get no treatments at all."

6 / 10
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5 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.