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Sofosbuvir and Depression: What Users Say

Brand names: Sovaldi

Depression: mentioned by 3 users (5.9%)

Based on user experiences from 51 Sofosbuvir reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

fatigue 21.6%
nausea 11.8%
headaches 7.8%
itching 7.8%
depression 5.9%
diarrhea 5.9%
insomnia 5.9%
irritability 5.9%
tiredness 5.9%
upset stomach 5.9%

Reviews for Sofosbuvir

Commonly mentioned side effects
  • ill...
  • Taken for 1 to 6 months
  • September 5, 2015

Sofosbuvir for Hepatitis C "My husband took the Sovaldi/ribavirin combination. He is free of hepatitis C now but is having major side effects still. My husband feels worse now than before treatment. He has severe bone and joint pain throughout his body. He has itchy, rashy skin, 30 lb weight gain, his thyroid is messed up and is now having to take medication for it, chronic fatigue, and has to nap daily. He has severe depression, difficulty dealing with people, explosive personality, difficulty concentrating, and more. He is unable to work due to the pain, inability to fill out paperwork or anything due to concentration issues. He has lost interest in things he loved to do. He naps several hours a day. We have been to different doctors with no one able to help..."

5 / 10
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34 Report
  • Wil...
  • July 22, 2015

Sofosbuvir for Hepatitis C "I have four days left of treatment, which has been for six months. The side effects have been mental for me. Anxiety, depression, insomnia, mood swings, irritability, and rage all come and go randomly. The virus was undetected at four weeks, and this is my first treatment. I won't know until three months post-treatment if the virus will stay gone, but it's gone right now. I am genotype 3A."

10 / 10
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22 Report
  • Bar...
  • Taken for 1 to 6 months
  • October 26, 2024

For Hepatitis C "I have been on medication for 2 months now, and I'm feeling fatigued, memory fog, brain fog, achy muscles, extreme lower back pain, but not able to get around very well due to muscles aching and cramping, also nausea and irritability, depression. I am willing to stick out the last month so I can make sure that it does what it's supposed to do and cure the hepatitis C."

8 / 10
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0 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.