Sofosbuvir / velpatasvir and Insomnia: What Users Say (Page 2)

• Any...
• Taken for 1 to 6 months
• December 8, 2024

For Hepatitis C "I was diagnosed with Hep C around 2001. I was finally able to start treatment in October. Luckily, tests showed no liver damage even after all these years. I have 4 weeks to go. The first few days on Epclusa were a little rough but not unbearable, mostly felt like I had the flu. I’ve had little to no side effects and already feel better than I have in 20 years. I have occasional headaches and insomnia. My viral load before treatment was over 2 million. After 6 weeks, it was down to 20, almost undetectable. My doctor is confident it will be undetectable after treatment. Four more weeks to go, and I am so happy to finally be able to live without this virus in my body. Whatever side effects I’ve had have been worth it. Also, my insurance covered most, and I received a coupon to bring my cost down to a $5 co-pay. I’d urge anyone to stick with the treatment. The meds are ridding your body of a deadly virus, so it’s bound to have a few effects, but for me, it’s more than worth it."

• Gre...
• Taken for 1 to 6 months
• November 2, 2024

For Hepatitis C "Epclusa cleared my Hep C in 12 weeks. Simple to use. Dose was one pill at the same time every day. I had been infected with the virus 56 years before, so to me, this was a miracle cure. The side effects were extreme tiredness, no appetite, brain fog, insomnia, diarrhea, and depressed mood. I was never anemic, probably because I had severe Porphyria Cutanea Tarda (PCT) with major iron build-up in my liver, which was the reason I went to the doctor in the first place. My major obstacle to treatment was the cost of the drug. I considered leaving the country for treatment, as the cost in America is outrageous. However, with the help of a foundation and a manageable co-pay, my Medicare paid for the treatment."

• jme...
• Taken for 1 to 6 months
• September 7, 2021

For Hepatitis C "I finished my 12 weeks of Epclusa almost 5 months ago. According to my last blood test 3 months after treatment, my Hep-C is gone. I am currently 69 years old and sure that I got Hep-C in the early 70s while in the Army. My Hep-C was detected around the year 2000. I did go through the ribavirin/interferon therapy at that time. It made me very sick and did not work. Epclusa caused me to have insomnia and horrible brain fog. I was not able to think rationally or make decisions for the whole 12 weeks of the treatment. My doctor said that the side effects I was having were not caused by Epclusa. Two weeks after finishing the treatment, my brain fog and insomnia went away. Although I am happy to be Hep-C free, I am wondering when I will actually feel better. I find myself getting tired much more easily. I am not able to recuperate from any strenuous exercise. I am reading these reviews just to see if anyone actually felt better when they completed the Epclusa treatment."

• Sta...
• Taken for 1 to 6 months
• August 2, 2021

For Hepatitis C "I am now on week 12 of Epclusa. I will be done this coming Saturday. My viral load went from 152,000 to zero in less than 4 weeks. I am happy that I'm cured, but I had bad side effects: insomnia, major anxiety and depression, paranoid thoughts, headaches, muscle cramps, feeling of being hungover (I no longer drink alcohol). I have made people annoyed with these side effects, so now I am going to have to tell them it was Epclusa, not me. Cannot wait until August 7th so I can throw away that pill bottle and be free. Glad I'm cured and my insurance covered, but it was a bear!"

• Fig...
• Taken for 1 to 6 months
• September 13, 2022

For Hepatitis C "Started August 12, 2022. First blood test at 11 days, and Hep C was non-detected. Felt so good. Stomach was better, had more energy. Felt better than I had in years. I am now a little over 30 days in, and side effects are starting to appear. Fatigue, insomnia, and stomach problems are back. Nothing I can’t handle. 2 more months to go."

• Sar...
• Taken for 1 to 6 months
• November 5, 2021

For Hepatitis C "I have one week left of Epclusa, genotype 1. I don't believe I had it long based on my liver damage, which was only 0.022. I have no idea how I got Hep C. I'm not an IV drug user, I know some, but it's not my thing. Over this past two weeks, I've had horrible knee joint pain, it's so bad I can't get comfortable in any position. I have suffered from insomnia prior to even starting the meds, but it's even worse now. My legs hurt so bad I can't get comfortable to sleep. Once I do fall asleep for a few hours, my knee pain goes away, and then it's back pain. I take my pill at 7 every night. I just am praying the pain in my legs goes away after I'm done, otherwise, I may go bonkers. I feel slightly depressed, no motivation, but no major headaches or nausea. So... it's very odd how the knee pain didn't start until this choice to be off the med."

• Rec...
• Taken for 1 to 6 months
• September 12, 2021

For Hepatitis C "I completed my 12-week course of Epclusa a little over 2 years ago now, and I felt it would be good for others to know what may happen after treatment. I had a few side effects that impacted my quality of life - brain fog, insomnia (2 hours a night for a LONG time), diarrhea, headaches, and fatigue. Some of those symptoms were worse at times than others, but I managed. My symptoms were actually worse after treatment was complete, with my sleep not normalizing for about 12 months, although it did slowly improve. My brain fog persisted for about 18 months, with my other symptoms clearing up within 18 months. I was clear of the virus after 6 weeks, but continued the full 12-week course. I am 47 (44 when I started the course) and active, but my fitness took a real hit during treatment and for the next year; it was a struggle to do much. I am now at a point where I feel very sharp-minded again and back to normal. The symptoms are manageable, well worth it for your future. Good luck, everyone."

• trt...
• Taken for 1 to 6 months
• June 3, 2025

For Hepatitis C "This is a follow-up posting (my first post was 6/2024 under TRT name, in which I narrated how I experienced absolutely no side effects during my treatment with Epclusa). I took Epclusa in Feb of 2024 and finished 3 months of treatment around the beginning of June 2024. I was tested then and again in 11/24 and just recently 5/2025. Every time, the test came back negative. I read so many reviews of the side effects such as brain fog, loss of appetite, rash, sleep problems, headaches, diarrhea. I can tell you all that I had never had those, not even 1 single time. I am currently 70 years old and I knew I had Hep C in my 30s, but I was so afraid of the interferon side effects (I read that some people lose hair during the treatment and some just gave up on completing interferon treatment), therefore, I waited until now, hoping that my liver does not develop cirrhosis. I wish everyone would be as fortunate as myself when taking Epclusa. Good luck to all of you."