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Sofosbuvir / velpatasvir and Insomnia: What Users Say (Page 2)

Brand names: Epclusa

Reviews for Sofosbuvir / velpatasvir

Commonly mentioned side effects
  • Dan...
  • June 27, 2021

For Hepatitis C "I have had Hep C for many years. I started the Epclusa before learning about the coupon, so I am hoping it will take care of the 20% copay my insurance doesn't cover and the $350 the specialty pharmacy charges for each shipment of 28 pills. I hope that can be worked out! So, it's been almost a month using Epclusa. I don't have many symptoms, but I have experienced short and minor ringing in the ears. The worst one for me is the lack of sleep, which I did not have much problem with before! I have significant psoriasis and am hoping it will be reversed or lessened! Regardless, at least I am finally doing something about this virus that has been cooking my liver and slowly making me sicker and sicker. I would like to spend more time with my grandkids and friends before I go! Oh, I have been sober 19 years this time, and 14 years a time before with a year in between, so I have definitely lived in the bonus round for most of the life I was on my way to give up! Take care, fellow travelers!"

9 / 10
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  • Lay...
  • December 12, 2020

For Hepatitis C "Male. Age 70. Got Hep C in the 70s. Could be longer because. Found out I had it in 2004. Entered a drug trial for interferon/ribavirin. Lasted 20 weeks on that and quit because of delusional thoughts, depression, sleep disorders, thyroid problems, exhaustion, aches, pains. I actually lost my job because I couldn’t cope with everyday tasks. My virus count went from 40 million to 2,000 and ALT/AST went to 3. I was informed by the doctor that if I had not cleared the virus in 20 weeks, I would not be cured by the end of the trial. So, I quit. My ALT/AST has stayed within normal range. And my viral load is still up and down but not over 40 million. Now that there are cures, I was thinking of trying a cure. My doctor is asking me to try Epclusa. But after reading all the reviews here, I don’t think it’s any better than the interferon/ribavirin (maybe worse). 12 weeks on this stuff might be easy. If I decide to take it, I’ll come back and leave a message. May the good Lord bless you."

5 / 10
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  • Sma...
  • Taken for 1 to 6 months
  • May 1, 2018

For Hepatitis C "Just finished my first month, and here is a breakdown. Week one felt tired. Week 2-3 felt great, had a few bouts of insomnia, have gained weight, and notice I want to eat all day. If I take the medicine on an empty stomach, I get a nauseous feeling, so I now take it with food. I've also noticed if I don’t drink my daily intake of water, I feel tired. Week 4, I’ve suffered from a slight headache in the mornings but not sure if it’s due to the medicine or a sinus/allergy problem."

8 / 10
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11 Report

Frequently asked questions

  • Jos...
  • Taken for 1 to 6 months
  • September 12, 2022

For Hepatitis C "I was diagnosed with Hep C 1a 10 years after I contracted it. When I heard the news, it hit like a ton of bricks, and I was nothing but fatigued with massive brain fog for an entire year. After all kinds of testing, my body seemed to be okay until months later, my viral load shot up to 3 million with liver enzymes very moderately high. I realized that Epclusa was needed and was fortunate to have it covered by insurance. I took the pill for 3 months and am cured of Hep C. The side effects are no picnic. The worst part for me was the insomnia. The fatigue and brain fog are manageable since I was already used to it from the virus. I suggest to stay as healthy as you can with Ayurveda, prayer, and exercise. Hep C is nothing to play with. Thank God for Epclusa!"

10 / 10
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  • jme...
  • Taken for 1 to 6 months
  • September 7, 2021

For Hepatitis C "I finished my 12 weeks of Epclusa almost 5 months ago. According to my last blood test 3 months after treatment, my Hep-C is gone. I am currently 69 years old and sure that I got Hep-C in the early 70s while in the Army. My Hep-C was detected around the year 2000. I did go through the ribavirin/interferon therapy at that time. It made me very sick and did not work. Epclusa caused me to have insomnia and horrible brain fog. I was not able to think rationally or make decisions for the whole 12 weeks of the treatment. My doctor said that the side effects I was having were not caused by Epclusa. Two weeks after finishing the treatment, my brain fog and insomnia went away. Although I am happy to be Hep-C free, I am wondering when I will actually feel better. I find myself getting tired much more easily. I am not able to recuperate from any strenuous exercise. I am reading these reviews just to see if anyone actually felt better when they completed the Epclusa treatment."

5 / 10
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  • Sta...
  • Taken for 1 to 6 months
  • August 2, 2021

For Hepatitis C "I am now on week 12 of Epclusa. I will be done this coming Saturday. My viral load went from 152,000 to zero in less than 4 weeks. I am happy that I'm cured, but I had bad side effects: insomnia, major anxiety and depression, paranoid thoughts, headaches, muscle cramps, feeling of being hungover (I no longer drink alcohol). I have made people annoyed with these side effects, so now I am going to have to tell them it was Epclusa, not me. Cannot wait until August 7th so I can throw away that pill bottle and be free. Glad I'm cured and my insurance covered, but it was a bear!"

9 / 10
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  • Fig...
  • Taken for 1 to 6 months
  • September 13, 2022

For Hepatitis C "Started August 12, 2022. First blood test at 11 days, and Hep C was non-detected. Felt so good. Stomach was better, had more energy. Felt better than I had in years. I am now a little over 30 days in, and side effects are starting to appear. Fatigue, insomnia, and stomach problems are back. Nothing I can’t handle. 2 more months to go."

10 / 10
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More FAQ

  • Rec...
  • Taken for 1 to 6 months
  • September 12, 2021

For Hepatitis C "I completed my 12-week course of Epclusa a little over 2 years ago now, and I felt it would be good for others to know what may happen after treatment. I had a few side effects that impacted my quality of life - brain fog, insomnia (2 hours a night for a LONG time), diarrhea, headaches, and fatigue. Some of those symptoms were worse at times than others, but I managed. My symptoms were actually worse after treatment was complete, with my sleep not normalizing for about 12 months, although it did slowly improve. My brain fog persisted for about 18 months, with my other symptoms clearing up within 18 months. I was clear of the virus after 6 weeks, but continued the full 12-week course. I am 47 (44 when I started the course) and active, but my fitness took a real hit during treatment and for the next year; it was a struggle to do much. I am now at a point where I feel very sharp-minded again and back to normal. The symptoms are manageable, well worth it for your future. Good luck, everyone."

9 / 10
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  • Sar...
  • Taken for 1 to 6 months
  • November 5, 2021

For Hepatitis C "I have one week left of Epclusa, genotype 1. I don't believe I had it long based on my liver damage, which was only 0.022. I have no idea how I got Hep C. I'm not an IV drug user, I know some, but it's not my thing. Over this past two weeks, I've had horrible knee joint pain, it's so bad I can't get comfortable in any position. I have suffered from insomnia prior to even starting the meds, but it's even worse now. My legs hurt so bad I can't get comfortable to sleep. Once I do fall asleep for a few hours, my knee pain goes away, and then it's back pain. I take my pill at 7 every night. I just am praying the pain in my legs goes away after I'm done, otherwise, I may go bonkers. I feel slightly depressed, no motivation, but no major headaches or nausea. So... it's very odd how the knee pain didn't start until this choice to be off the med."

6 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.