Plecanatide for Chronic Idiopathic Constipation User Reviews (Page 5)

• Hystr...
• June 6, 2017

Trulance (plecanatide) "Week 1 great, week 2 very constipated. Went back to Dr and took magnesium citrate to clean out. Week 3 had to clean out again after 3 days. Week 4 today backed up again. Took 2 pills feel better. Ahh. See how long this lasts."

• Anonymous
• August 24, 2017

Trulance (plecanatide) "Experienced diarrhea and muscle pain in my left arm. Increased blood pressure rapid heart beat with only 1/2 doze of 3mg pill. Also felt chest pressure from tightness in chest. Discontinued the drug after speaking with my dr."

• NTHC
• Taken for less than 1 month
• March 28, 2023

Trulance (plecanatide) "I take Motegrity daily and just started Trulance every other day. I have a bowel movement within an hour of taking the Trulance. I was using amitiza and Motegrity but it was slow to work. I also tried Linzess in the past which made me super nauseous and abdominal pain. I am getting some diarrhea from the Trulance but I’m hoping my body gets more used to it with time."

• eslu
• August 18, 2017

Trulance (plecanatide) "I received a one week sample supply from my doctor, worked fine, I purchased this overpriced drug only to find out that after the first week it worked too well. Terrible drug, at this point I cannot even take one pill without loosing all control of my bowels. Do NOT recommend. Hard to believe this was approved by the FDA"

• Relie...
• Taken for 1 to 6 months
• May 4, 2022

Trulance (plecanatide) "Have been dealing with constipation since I had weight loss surgery 15 years ago. Tried everything, bag enemas, then fleet liquid glycerin enemas along with Amatiza. I felt like my life was controlled by having to make time to go or not knowing when it would go. I started Trulance about 4 months ago. Life changed forever. Since I’m working from home now since COVID I’ve had the luxury of being able to experiment with this. After 4 months of every day one pill I switched to 1/2 a pill every day and it’s just as effective which is good because at $150 a month now it lasts two months. Pooping still occupied most of my morning but once it’s done I’m pain free and no bloating or anything. I’ve kind of figured out that I eat my cereal first then take it then I have about an hour and a half to go to the store or do whatever before I’m gonna need the bathroom if I take it with half my iced coffee and then the rest of my coffee when I get home from the store. Worth it!"

• Runru...
• Taken for 1 to 6 months
• January 16, 2018

Trulance (plecanatide) "My doctor also put me on Trulance, after banding all my bleeding hemmorhoids. If I take it early in the day it seems to do nothing, if I take it in the evening, it works, it works too well! The pills are very tiny, but I can bite off about a third of one and still have to run, run, run to the bathroom. I think I'm going to try taking a bit of one every other day and see what happens. Oh and I took it for about a week before it started to work. The longer I took it the better it worked. I don't like almost pooping myself every day, but I guess it's better then not pooping at all! I'll experiment with it and see if I can get the right dosage. Linzess didn't work for me at all."

• Trula...
• Taken for less than 1 month
• January 28, 2022

Trulance (plecanatide) "Do not take this medication under any circumstances. I paid $500 for an RX, took 1 pill at late evening. Woke up a 3 am with bedclothes and bedding soaked with diarrhea leaving an embarrassing and unsanitary condition that took hours to clean up. The problem did not stop there. The"cleansing" went on for three solid hours non-stop. I have been nauseous and without appetite for 4 days. Lost 4 pounds from my normal body weight of 98. My insurance company insisted I try this instead of my regular medicine which I have taken for years or they would not cover my regular prescription. This medicine is poison for people with my issue. Now I am out $500 to satisfy big pharma need for a "trial" victim."

• Jury...
• May 23, 2018

Trulance (plecanatide) "Donna C mentioned sinus problems. My sinus issues (post nasal drip in particular) were result of reflux & hiatal hernia. When bad PND got worse. Nexium greatly improved things! I figured out myself-tons of online research. My gastro said he'd heard that can be the case. Unfortunately, doesn't fix the greater problem but thought it might be useful. I have severe constipation thought to be result of scar tissue in abdomen-1X had complete obstruction that resulted in resection. Have tried every possible med. Experience with Trulance was initially positive-lasted about 3 days. More gas than usual but moved my bowels more completely and more normal looking. Since has been almost explosive diarrhea, though not as terrible as with Linzess. Giving this a bit more time but, like others, really just so tired of how this controls and limits my life. Still on trial packs but RX is approved and waiting for me to p/u."

• draym...
• Taken for less than 1 month
• January 13, 2019

Trulance (plecanatide) "I am on my second dose of Trulance and still waiting for it to work. My doctor gave me samples to take while I wait for my insurance to approve the drug coverage. I am tired of medication not working for me. I was hoping this would work since it was new but nothing yet."

• jillj...
• September 14, 2017

Trulance (plecanatide) "Just recently started taking this, there's been some belly rumbling, but no BM. This report is about side effects of severe ringing ears, systemic sensation of itchiness like being bitten by little bugs. It's not severe like the ringing ears is, but its still kind of creepy. It seems the FDA did not do their job. Somebody's making money at consumer risk. The doctor gave me a sample..."

• Kayla...
• August 11, 2017

Trulance (plecanatide) "2 days of this medicine and I have been extremely sick! Non stop going to the bathroom, cramping, nausea. It's unreal. I'm skeptical to stop bc what if I needed the cleanse? But I can't take this sickness"

• Gym...
• July 1, 2017

Trulance (plecanatide) "Started it 8 days ago. 4 days nothing. Had to use magnesium citrate pills 3 in morning and 3 at night with the trulance. My doctor wants me off magnesium citrate and just rely on trulance ( new Dr doesn't know my how my body shuts Down yet) gives me bloating and gas where magnesium citrate didn't. Just pleasing the Dr till more tests are run."

• Anonymous
• Taken for 6 months to 1 year
• October 11, 2023

Trulance (plecanatide) "Trulance is an amazing drug that has been life-changing for me. I was suffering from such severe constipation that I could barely eat, had horrible abdominal cramps, and was losing too much weight. Now that I am taking this medication, I am pretty much back to normal. Some people who give the drug a bad review because it works REALLY well for constipation probably didn't need it as much as I do!"

• Just...
• Taken for less than 1 month
• August 12, 2018

Trulance (plecanatide) "I tried one tablet around 2pm and within the hour I was on the toilet with a runny evacuation, then bloating, then more dirrahea, more gas, even more runny evacuation. This lasted the until maybe 8:30pm. That night I experience pains running through my body, my arms and legs hurt so badly. It’s hard to describe, not sure what that was. I think it was from the trulance medicine so I’m scared to take another one. I had a loose evacuation the next evening and this was without taking another tablet on day 2. I’m considering taking the tablet every other day but not sure. Someone mentioned weight that is a huge neon green , orange and red flag for me to stop I want to loose weight not gain it. Plus I’d think cleaning out would reduce ones weight. Anywho my verdict is on the fence for now I don’t know I am elated to have a bm given I can maybe once a week."

• ayse
• October 6, 2021

Trulance (plecanatide) "I have been on a high dose of Linzess and finally with probiotics got on a regular schedule. Due to insurance issues I was switched to Trulance. Trulance so far has caused constipation, extreme lethargy, headaches, and a weird depression. I would rather go back to linzess and have liquid stools than have no stools at all. I have had to drink tons of miralax to get any relief . I don't think the Trulance does anything what so ever but have bad side effects."

• Sher
• Taken for less than 1 month
• April 21, 2018

Trulance (plecanatide) "The very first time I took Trulance was in the late afternoon since that's when I got home from the Doctor who gave me samples. About an hour or so later I started having increased diarrhea that went on for 3-4 hours. So I picked different times to take it. Next time wasn't so bad but after a week and a half it just doesn't work! So now I will experiment taking it at bedtime. Not giving up yet"

• Lin
• Taken for less than 1 month
• December 19, 2020

Trulance (plecanatide) "I just started Trulance. Family members are on it with no problems. I wanted to stop senna as it requires more and more over time for me. It worked (first day). I do want to warn about Miralax (see the yahoo group called Miralax. It can cause burning bladder. It did with me and took 3 months to stop. I took it 9 months before getting the burning. So I REALLY need this to keep working as it did today. And I did also only take half as my system seems to need less dosage of all meds. I'll let you know as soon as I'm on it for awhile."

• Trick...
• Taken for less than 1 month
• March 20, 2021

Trulance (plecanatide) "My insurance stopped coverage on the Amitiza that I had been taking which was working and made me try Trulance. I couldn’t even make it through a month. I would rather take nothing at all. The horrible pain, the never ending gas that did end up with a bowel movement but with the overwhelming urge to strain. Even then only 2 or 3 bm a week compared to 1 bm a day that I was accustomed to."

• chris
• Taken for 6 months to 1 year
• June 18, 2020

Trulance (plecanatide) "I was taking for over 6 months. My insurance from my employer paid then the savings card kicked in. In the middle of the program-without telling anyone from March 2020 to April 2020 the company decided they were going to pay less and not tell anyone. What a jerk move. thanks for nothing"

• Rsano
• January 9, 2018

Trulance (plecanatide) "I have taken linzess and amatiza with no success so I was prescribed this medication Friday. Took it at 5pm didn't 'work" until 7. Saturday and Sunday it also took two hours to pass through my system. Monday I took it at 4:30 at 6:30 I had drank at least 24 oz of water to help it pass thru.....still nothing but getting more and more bloated. I took another pill at 6:45 hoping it would work. Drank another 24 oz of water ....at 11 after doing anything possible to stop my worst bloating belly ever...(walking, rubbing my belly, water) so I'll keep going but not feeling like this is going to help."

• Merdith
• Taken for less than 1 month
• December 28, 2017

Trulance (plecanatide) "This medication caused severe diarrhea. Took one pill and had constant diarrhea for 27 hours straight along with stomach pain. My bf is a gastroenterologist and hadn’t seen this reaction before. Go figure but this medication doesn’t work for everyone."

• Sherry
• January 18, 2022

Trulance (plecanatide) "I’ve had constipation for as long as I can remember. Things would work but my body would get used to them and it would stop. I have IBS with constipation. I take muscle relaxers but not every day. When I took Trulance, my first few days I had to wear a diaper to bed! Then if I took it every few days it worked better. Then it didn’t work. Now I’m taking it every day. I am very bloated, nauseous, and have pain in my colon. I was hoping this would be the answer. Lincess did nothing. The Dr couldn’t believe it! Me neither."

• Grey
• Taken for 1 to 6 months
• January 31, 2022

Trulance (plecanatide) "I found it!!!! Trulance is my miracle. After months and months of prayer to finally rid myself of my condition, I finally gave in and tried this. Originally I tried all these other common drugs (Linzess, Motegrity, amitiza) and either the side effects were horrible or it only worked temporarily. Trulance works with my insurance and it works with my bowels. I take it in the morning with coffee and water to wash it down. Usually within a few hours I feel actual bubbles in my digestive system meaning it’s normal! Finally it works. If I know I have a shift at work I don’t take it in the morning usually because the stress and being on my feet won’t allow me to relax. But I never knew how effortlessly happy I could ever be in my entire 23 years of life. Thank you God!"

• Anonymous
• Taken for less than 1 month
• April 14, 2022

Trulance (plecanatide) "My doc gave samples. After first pill, no issues. I took it in the evening and had a small BM next day. Not that impressed, I took second pill the following evening. The next day, another small BM. I was hoping for more output. However, also woke up with a headache that just lingered the whole day. At night, after dinner and before taking my third dose, I began experiencing the worst colic pain and cramping of my life! I was writhing in pain!. I could hear my bowels gurgling from time to time, but no diarrhea or nothing else was coming out, no matter how long I tried on the toilet. Just pain and cramping all night. Obviously I skipped my third dose as I did not want to risk more nightmarish pain! The next morning I finally was able to have two small bowel motions, but I also felt wiped out and still feeling dull pain and cramping. Have not had the chance to reach out to my doctor yet, but pretty sure I am passing on this drug!"

• Pookie
• Taken for 6 months to 1 year
• February 8, 2021

Trulance (plecanatide) "I find out of 7 days of taking it a week it works only 1 or 2. I can't have a BM without taking the pills. This is my last resort before a total colon removal. This problem is a result of having taken Aimovig for my migraines."