Ocrevus for Multiple Sclerosis User Reviews

• Ala...
• Taken for 1 to 6 months
• June 24, 2023

"I was on Gilenya for 7 years. Because of my insurance, I had to switch to Ocrevus. I was excited because it has better results based on the studies. Two days after my first infusion, I got strong fatigue and a feeling of pressure in my brain. It stopped after 10 days. I decided to do the second infusion 15 days after. Exactly the same experience. I got the exact symptoms two days after the second infusion. It lasted 8 days. - pressure in my brain - hard to think, focus - feeling of falling when I close my eyes. Two weeks after, for no reason, I got the same experience again for 15 days."

• Ros...
• Taken for 1 to 6 months
• May 9, 2023

"This is the first time on Ocrevus, and I am experiencing lots of side effects, such as neuropathy in hands and feet, neuropathic pain in the back of my head, and flushing. These side effects are all happening in the time between the first two half doses and thereafter. I am not sure if this is the right medicine for me."

• Eri...
• October 30, 2022

"My first dose, I felt horrible, and my MS progressed. I had to stop driving. Second dose, same feelings, MS progressed to not being able to walk well, even with a walker. Doctor asked me to take another dose, so I did. I have been stuck in bed ever since. I have to use a wheelchair and a lift to be able to do anything. Please make sure if you are a natural redhead to really think about using this medication."

• Joh...
• Taken for 1 to 6 months
• October 15, 2022

"Garbage! One month after the first infusion, I got about 100 moles and warts all over my body, and more are appearing every day now. A few weeks later, I got more MS attacks, which left my toes and mouth numb."

• Ano...
• Taken for 6 months to 1 year
• September 22, 2022

"Only made it to the second full dose of Ocrevus, and the pneumonia bouts began. I was hospitalized constantly. Ten bouts of pneumonia later, sepsis in addition, twice. This drug nearly killed me and has weakened my immune system so much that I can't take anything for my MS. Developed pulmonary hypertension by the seventh bout of pneumonia. Stay away from this drug. Other than MS, I was in good health. Spent my 40th birthday in the hospital. Now every time I get a fever, I freak out. I have a 40% chance I won't make it within five years now. Respiratory infections are a side effect, it's in the insert for it. The ER doctor tried to argue with me about it, understandably so, as it isn't listed under side effects if you simply Google it. I found it buried in the insert under the study findings. Physicians need to be made aware of this. Guaranteed quite a few people have died from this, and the cause of death is listed as COVID. Beware."

• GGG...
• Taken for 1 to 2 years
• June 12, 2022

"Wish I had found this site before taking the infusions. Started feeling some worsening of the side effect symptoms during the 2nd infusion, so I googled patient reviews that confirmed to me it wasn’t my imagination, as the neurologists say and refuse to listen! The worsening of my symptoms and some new ones includes reduced mobility and increased fatigue and sensations, but what jumped out at me was the review on here about TMJ! That reminded me I had experienced incredibly painful TMJ after the first infusion, but had never related it to the infusion, as neurologists unanimously say it wasn’t! I had forgotten about it until it returned immediately after infusion 2, even worse, so despite not being keen on medicating, I’ve had to resort to taking anti-epileptic Tegretol in addition to Pregabalin to try to manage excruciating pain. I’m never taking Ocrevus again, but will the new/worse effects ever go away?"

• Kim...
• Taken for 1 to 2 years
• June 11, 2022

"Started March 2020. Did great on Tysabri with severe weight gain, hair loss, gum pain, dental issues, edema, thyroid nodules growing like crazy, extreme fatigue, had to take medical leave from work, can’t sleep, rashes, hard red flaky spots on skin, sweating, rib pain under breast unbearable. They injected me with cortisone. I can’t work out, heavy breathing, legs feel heavy with little activity. Liver enlarged, trace blood in urine, kidney stones for the 1st time with 2 surgeries. 5 months later, more stones. No one recognizes me, skin is dry, nails brittle, red itchy eyes, joint pain, severe anxiety, headaches, heart palpitations, abdomen distention, random bruising especially on feet. Feet very hot and swollen, hands swell, constipated, nose bleeds, dizzy. I have lost my entire quality of life, I was so active. Tests come back “normal” but drastically not normal compared to before I started. Poison."

• Mas...
• Taken for 1 to 2 years
• May 26, 2022

"My daughter was diagnosed with MS when she was 16 years old, about 24 years ago. She tried Avonex, Copaxone, and some of the other medicine out there. In 2018, her neurologist suggested she try Ocrevus. She began having seizures after the first dose, which she had never experienced before. Her doctor suspected Ocrevus may have been the cause of the seizures yet continued to schedule her for infusions. She developed excruciating headaches and terrible jaw pain, which never resolved. It's interesting because I don't see it advertised on television where we live."

• Mic...
• Taken for 1 to 2 years
• April 20, 2022

"I had 3 goes of this drug. In March 2022, I had double vision. I'm pretty sure it was from this drug. I'm staying to natural living rather than take this drug."

• Bad...
• Taken for less than 1 month
• April 5, 2022

"I will never go on this or any other MS medication again. This one, after one dose, put me in AFIB. Into the hospital I went!!! Now I have a slight tachycardia! I had no heart issues before this drug."

• Ful...
• March 24, 2022

"I was diagnosed with RRMS in 2015, 2 years later put on filgolimod, was on that for 3 years with no new lesions but symptoms progressively worsening, re-diagnosed with shadow MS and put on Ocrevus. I had the first 6-month infusion and greatly regret it. Before this treatment, I could walk unaided, ride my horse, and mow my lawn, now I can drag my feet for 15 meters at a time with crutches if lucky. I can't control my hands to cook anymore and consider it a great achievement to make it to the toilet without wetting myself. I just did the 1 full 6-month treatment and now have been re-diagnosed with SPMS. I am now just hoping that without this stuff in my system, I could possibly, hopefully get back to how I was before I took Ocrevus."

• MSi...
• Taken for 2 to 5 years
• March 12, 2022

"I had 4 infusions, 2 years basically. No initial bad symptoms first time. Noticed a huge onset of symptoms about 2 months prior to the second infusion. Afterwards, back to regular symptoms. That lasted for 4 months also. Then all hell broke loose in my GI system. I haven't been normal since. I've lost almost 50 pounds, devastating my powerlifting hobby. I can't hold food in my body, so I'm always exhausted. I don't blame my doctor, and I know it's worked amazing for some people, but it is not a miracle. Please stop advertising this dangerous drug as a cure for MS. I take Gilenya now, but I will never be the same."

• MWT...
• Taken for less than 1 month
• March 3, 2022

"So my mother took Ocrevus, she was diagnosed with MS in 2008. MS was a constant battle for her. One of her specialists prescribed Ocrevus to her. When she told me and my wife about the drug, she explained what the drug did, and basically it gets rid of your immune system, and the drug was so potent that you could not let the pill touch your skin. She would have to put on a nitrile glove before removing the pill from its container. Well, after she finished the cycle of meds, her health declined catastrophically and fast. Within a year, my mother was dead at 52 years old. I strongly urge you all to stay far away from this medication. It is not a miracle drug, it is a dangerous drug. The medication destroyed her heart, and at the end of her life, she was in agonizing pain. She couldn't breathe, couldn't walk, and had in-home hospice care. Unless that's what you want, I would tell any doctor that recommends this to get lost."

• Phi...
• Taken for 1 to 2 years
• February 9, 2022

"Funny how a number of positive reviews question the bad ones outright. Sort of reads like a promotional campaign. Ocrevus is garbage! It’s complete crap!! I don’t understand for the life of me how this stuff was approved. I was diagnosed in 2014. I was put on Aubagio, and I was very steady for four years. By 2018, I started developing a limp. Caught up in all the promotional lies, I thought this garbage would fix my limp… From 2018 until 2020, I did four infusions. The biggest mistake. I got worse in every aspect. Now I fully understand wtf MS is, and Ocrevus was the driving force. I stopped taking it in 2020. I spent all of 2021 on nothing, as I now use a scooter and can’t walk anymore. I’m trying to lower my EDS score through physical therapy so that I could be eligible for Mayzent. Oh how I wish Mayzent was my next move from Aubagio. Sadly, was not approved in 2018 in Canada."

• Mic...
• Taken for less than 1 month
• January 25, 2022

"It has been 5 years since one Ocrevus infusion for RRM... still not back to pre-infusion status. Immediately after the first infusion, I was in a severe TIA confused state. Went from walking with a cane to a wheelchair immediately after Ocrevus. Worst experience of my life. In the last five years, I have been back to see my neurologist once. Absolutely lost total faith in the pharmaceutical Russian roulette called MS immune-modulating treatments. Expensive, risky, not what they tell you. Didn’t work. Harmed me. No one cared. They only want to hear positive reports. It is all about the money. My experience has been treated with indifference. Good luck to all/"

• Eri...
• Taken for 1 to 2 years
• January 12, 2022

"I have been on Ocrevus nearly 2 years. Just had brain MRI. Shows new and larger lesions. It never helped with any of my MS symptoms (fatigue, pain, horrible insomnia, twitching, poor balance, anxiety, trouble with concentration, bad memory). If anything, these symptoms have gotten worse. And now it shows my MS has only progressed since taking Ocrevus. Extremely disappointed with this treatment."

• Awf...
• Taken for 2 to 5 years
• October 11, 2021

"Took away my mobility. 3 years on this stuff and I finally clicked I was fine before starting this."

• Mar...
• Taken for 1 to 2 years
• September 12, 2021

"After my dx, I chose Rebif. One year later, my neurologist suggested a new treatment that would alleviate the muscle aches, tiredness, stomach pain, runny nose, skin discoloration, and elevated liver function test associated. When I started this drug, I tolerated the introductory split dose but should've stopped after the 1st full dose WHEN I STILL HAD THICK HAIR BEYOND MY SHOULDERS! Every infusion to follow is split in half, they say the symptoms will subside. They didn't, they got worse, and now I'm somewhat of a weak hermit. My stomach and calves hurt, I don't recognize my face or my handwriting, and when I talk to them about the side of my face that droops, the hemifacial trigeminal twitching, they attribute it to caffeine! My skin is dry, my scalp itches, and I develop a rash on my chest, neck, and ears after infusions. I can see my scalp, my hair is thin, I have headaches, no strength, and zero energy. I don't care about lesions, and I don't mind wearing face masks."

• Ocr...
• Taken for 6 months to 1 year
• August 26, 2021

"Ever since I started using Ocrevus, after each infusion I was weaker, my balance was off even more."

• Anonymous
• July 26, 2021

"My boyfriend was diagnosed in 2002, was on Rebif for a few years until he was switched from RRMS to SPMS, and back then nothing else for him. When Ocrevus came out, everyone raved about it. Thom had been without meds for 10 years, so he was pretty anxious to start, especially with all the positive reviews. The first half, he started to experience more leg pain, after his first full dose, he became so weak he was bedridden, could not roll over in bed, could not hold himself up in a chair, I would strap him in. All of his symptoms went into overdrive. His doctor and everyone from Ocrevus groups said give it time. He was on this poison for 2.5 years, along with all of his symptoms worse and the weakness he had hair loss, extremely dry flaky skin, skin lesions, bacterial infection in his nose, extreme constipation. It's been 19 months since his last infusion, and thank God he is 95% back to his baseline. All these doctors are calling it progression, but in actuality, it's this poison."

• Mad...
• Taken for 2 to 5 years
• July 26, 2021

"I started this medication in 2017 and finally quit in September 2020. Although my MRIs remained stable, I declined physically. I walked into my first infusion unaided, now I need a full-time cane/walker and a scooter. My mobility has been most affected, other symptoms, which I could have lived with, include hair loss, fatigue worse than usual, and cystic eye styes. The worsening of mobility, balance, and weakening of muscles has made choosing this drug the worst decision I ever made. If I didn’t do CrossFit every day, I’m sure I would be bedridden."

• Old...
• Taken for less than 1 month
• July 11, 2021

"Had just taken the 2nd initial dose. About a week later, all heck broke loose with my body. I cannot say it was the Ocrevus, but it was the only new thing. Last time I had a seizure was 2016. About a week after the 2nd initial dose, I experienced a raging UTI and started having seizures. Long story short, I was in the hospital for a week, rehab 5 days when they called my wife to say I was unresponsive, then back to the hospital for 1 more week. During this 3-week period, I experienced, that I knew of, 4 more seizures. Ocrevus is not for me."

• Car...
• Taken for 1 to 2 years
• July 5, 2021

"Unfortunately, Ocrevus made all of my MS symptoms worse and even gave me some new symptoms. I was on Ocrevus for 3 infusions (1.5 years). After one year of being off of Ocrevus, I am back to my baseline. This drug gave me incredibly bad pain - muscles and joints, including Trigeminal Neuralgia (never had it before O and it's gone now). I felt nauseous on this drug, had horrible migraines, and the weakness in my legs increased. It also gave me cystic acne. I am much better now that my WBC is back up, but it took a whole year for my labs to normalize and to feel better. I thought it was an awful drug, but everyone is different! I had no new lesions, but I did progress and feel worse than before I started taking it. I will say that the neuro didn't report my adverse effects even though I was on a clinical study - so I am wondering if they only report lesion activity."

• Nik...
• Taken for 2 to 5 years
• July 5, 2021

"While I was on Ocrevus, my MS symptoms got much worse. I thought my MS shifted to SPMS because I was progressively becoming disabled without any new lesions. I was thinking of buying a wheelchair. I didn't have any more 'good days.' My brain didn't work. I was depressed. I asked my doctor to switch my med to Mayzent because it was the only medicine for SPMS at that time. After I stopped Ocrevus, I gradually felt better. Unfortunately, Mayzent caused severe side effects, and I had to take Ocrevus again. Then I became so sick again. At that time, I was so sure that Ocrevus was making me sick. After stopping this medicine completely, I am back to my baseline. I can hike. My brain works. More good days than bad days. The drug company still doesn't claim worsening symptoms as its side effects from all of these people complaining. Very disgusting."

• FD3...
• Taken for 1 to 2 years
• June 3, 2021

"When Ocrevus first came out, it was practically touted as a ‘miracle drug,’ and it seemed like everyone with MS wanted to get on it. I had such high hopes when I read that not only did it do a great job in reducing relapses and new brain lesions, it significantly slowed progression and even dramatically improved a lot of patients’ symptoms. Well, in the almost two years I’ve been on it, all it has done for me is make my walking a heck of a lot worse. Prior to Ocrevus, I used to enjoy going on hiking trails even though I used a cane. Now I can barely hobble around my backyard. Rather than slowing down progression, it seems to have sped mine up. I fear that if I continue to stay on it, the day will come when I won’t be able to walk at all anymore. Really disappointed and disgusted by this drug."