Zejula and Joint Pain: What Users Say

• Jes...
• Taken for 1 to 6 months
• October 7, 2020

For Ovarian Cancer "I've been on Zejula now for 3 months. Side effects are getting slightly better. 300 mg at bedtime due to persistent nausea prior to starting this drug. I take it and feel so tired that you would think I would sleep, but I lay down and my mind won't turn off. Usually drop off at 1 a.m. then wake at 4:30 a.m. Sometimes, I can get back to sleep. Really bad fatigue and joint pain. H&H are slowly dropping but not critical. I do like the fact that my white count, while low, does not need Nupagen. I have trouble concentrating and focusing on things. Motivation is a thing of the past. CA125 is climbing since I started the drug. I see the oncologist tomorrow for a 3-month check-in."

• Lia...
• Taken for 6 months to 1 year
• March 26, 2019

For Ovarian Cancer "My initial experience with Zejula was terrible, plunging platelets and other blood components, fatigue, joint pain, dry mouth, sleep disruption, more fatigue. I could not handle my work or my life. Had to have two transfusions. Tried two hundred mg. I watched carefully this time. Then a precipitous drop in platelets and other key blood components again. Intolerable fatigue. Had an allergic reaction to one of the transfusions. My optimism was sapped. Started 100 mg despite these experiences eleven months ago. Persistent anemia, depression, fatigue, and joint pain. Now tardive dyskinesia. Still hoping."

• Coo...
• Taken for 6 months to 1 year
• July 5, 2021

For Ovarian Cancer "Diagnosed with 3B ovarian with peritoneal and 11 lymph nodes involved. I had Carbo Taxol, then surgery and finished with more Carbo Taxol. I’ve been on Zejula for 9 months. It’s pretty tolerable. My side effects have been awful insomnia, constipation, some joint pain, tiredness, some nausea, and stomach pain, and most recently some itching. I am 60. I push myself to exercise 4-5 days a week and work part-time in a retail setting, so lots of steps. Yoga is helping the joint pain. My CA 125 is holding steady at 5-7. Platelets are staying around 220. Hoping to stay on it at least 15 more months to make it to the 2-year mark. Current dosage: 3 pills daily."

• OVC...
• Taken for 1 to 6 months
• May 10, 2018

For Ovarian Cancer "I had very low platelets, and I was unaware of that. Symptoms: gum bleeding, joint pain, I was tired, some problems to sleep, high blood pressure. CA 125 went up, tumor grew, this medication did not work on me. 3 pills every day at the same hour. I do not have nausea or vomiting."