Nilotinib and Nausea: What Users Say

• jud...
• Taken for 2 to 5 years
• April 21, 2013

For Chronic Myelogenous Leukemia "I was diagnosed with Chronic Myelogenous Leukemia in October of 2010. I was prescribed 600 units of Tasigna per day - 300 AM and 300 PM. I was in remission in 12 days - thank GOD. I am on Medicare and get help with my co-pay from PSI. I have mild nausea when I first take the pills, mild constipation, and some shortness of breath, but I also have COPD. I have been taking Tasigna for 2 1/2 years now and am just starting to notice my hair is thinning. I was told I have to take it for life. I thank GOD every day for this medicine and will gladly endure the minor side effects in exchange for a longer life."

• Mis...
• Taken for 2 to 5 years
• September 1, 2015

For Chronic Myelogenous Leukemia "I have been on Tasigna for just over 3 years now (300 mg x 2 times a day). Tasigna worked for me within a few weeks. I have been in remission for basically the entire 3 years. As for the side effects, I feel sick to my stomach, tired, severe leg and arm pain. I can't walk too long without needing a break. I went from working full-time to not working at all because I am so tired all the time.... but hey, I am in remission and alive, so is all the above really a problem? Nope."

• Anonymous
• May 13, 2011

For Chronic Myelogenous Leukemia "2 years on Gleevec with minimal positive effect and maximum side effects. 3 months on Tasigna and swelling gone, leg pain gone, nausea gone, I feel good. Tests show much improvement and my doctor is now very optimistic. Twice a day regime and eating times are small problems. My libido is back."

• McL...
• March 25, 2010

For Chronic Myelogenous Leukemia "Effective drug. The 12-hour thing is a pain, as is the eating discipline. Must affect hemoglobin levels, as feeling tired is an issue. Any effort, i.e., walking up a slight incline, can make you feel nauseous. Can't complain because it works for me."

• Ian...
• Taken for less than 1 month
• November 30, 2016

For Chronic Myelogenous Leukemia "Started Tasigna on Thursday morning. I'm diabetic and became severely hypoglycemic on Saturday. Stopped taking diabetes meds, and that improved, but I had a stomach ache and nausea so bad I was dry heaving for 3 solid days because I couldn't eat. Went 3 days without sleep because I was curled up around the toilet. I stopped taking it on Monday evening. My reaction to this drug felt like what I envision chemo to be. I go back to my doctor tomorrow to come up with an alternative treatment plan. I'm now scared to start another med for fear of similar reactions, and I don't want to imagine being this sick the rest of my life. Very happy and envious of all the success stories."

• Bal...
• Taken for 1 to 6 months
• March 30, 2021

For Chronic Myelogenous Leukemia "This is my third month of having Tasigna 600 mg/day, felt every symptom that is mentioned, but all gone. I feel nauseated from the last three days, and it is not going anywhere. Though I have felt it earlier, but it was gone. I will get a PCR test of BCR-ABL at the end of the third. Let's see, hopeful molecular response will be good."