Metoclopramide and Depression: What Users Say (Page 2)

• Ann...
• August 28, 2021

For GERD "I was given this drug for sickness in 2019. I was on 10 mg per day, and at the beginning, it worked a treat. After a month of taking it, I began to feel down and anxious, having never experienced depression and anxiety before, I wondered what was going on. It got worse and worse, and it was only when I read the side effects (1 in ten people suffer depression as a side effect) that I realized what might be happening. My GP advised me to stop the drug. I am now on antidepressants and have to deal with anxiety on a daily basis. I've gone from someone who was fine emotionally to someone who is far from it. I believe this is a result of metoclopramide."

• Yep...
• Taken for less than 1 month
• April 20, 2021

For Nausea/Vomiting "As most of the reviews listed here, this drug is awful. I had nausea and vomiting for several days and was given a Maxolon injection. Twenty minutes later, I had a panic attack. Never had one prior in my life. Eighteen months later, I’m still suffering from anxiety and depression and on medication to combat these conditions. Avoid this drug at all costs."

• Whe...
• September 8, 2016

Metoclopramide for Lactation Augmentation "I started taking this drug about a month ago. So far, knock on wood, no side effects, and it works great! I feel so proud to be able to feed my new daughter! I have seen lots of reviews about depression, so please be careful!"

• 69M...
• Taken for less than 1 month
• November 7, 2016

Metoclopramide for GERD "A word to the wise: be sure the doc knows what medicines you are on before you take this medicine. I have acid reflux really bad. Went to the ER, couldn't breathe, lost my voice, felt like I had an extremely tight chest. They diagnosed me with GERD, I said I think I have caught the stomach bug. The ER doc gave me two shots of Reglan and a prescription to fill. Next morning I take my first dose, spend the next two days confused, anxious, down, and depressed. Looked up side effects of Reglan and realized it didn't mix well with the meds that I take daily, and I had been given a little too much at once. After taking a couple of days of Mucinex for congestion, Mylanta for my stomach, and using an inhaler to breathe, three days later, stomach bug gone!"

• 69M...
• Taken for less than 1 month
• November 7, 2016

Metoclopramide for GERD "A word to the wise: be sure the doc knows what medicines you are on before you take this medicine. I have acid reflux really bad. Went to the ER, couldn't breathe, lost my voice, felt like I had an extremely tight chest. They diagnosed me with GERD, I said I think I have caught the stomach bug. The ER doc gave me two shots of Reglan and a prescription to fill. Next morning I take my first dose, spend the next two days confused, anxious, down, and depressed. Looked up side effects of Reglan and realized it didn't mix well with the meds that I take daily, and I had been given a little too much at once. After taking a couple of days of Mucinex for congestion, Mylanta for my stomach, and using an inhaler to breathe, three days later, stomach bug gone!"

• Pre...
• Taken for less than 1 month
• August 20, 2017

For Nausea/Vomiting "I was prescribed this medication for severe morning sickness about a week ago after going to a walk-in clinic. I was given a shot at the clinic, and it seemed to work. I took the medication for a few days and then suddenly began to feel extreme depression and anxiety yesterday, but less sick than before taking this drug. My vomiting has decreased to once a day on this medication, and I can sleep through most of the night now without getting sick, but I feel very anxious, chills, and hot flashes, and really depressed. I am going to stop this medication immediately, as I would rather vomit all day than feel this bad."

• Lil...
• July 4, 2017

For Nausea/Vomiting "I have pregnancies characterized by extremely severe hyperemesis gravidarum. I spend most of my pregnancy nil by mouth in the hospital and then get a PICC line. They gave me Reglan, and let me tell you, it made me severely depressed and suicidal. It did not touch my NVP either. The combination of a very adverse reaction to this medicine and malnutrition caused me to terminate my wanted and planned pregnancy. I have dealt with severe HG before and have a 2yo. I did not realize this medicine caused this until recently. I was given it before a surgical procedure. It made me out of my mind! I felt like jumping out of my skin. I tried to rip out my IV and leave the hospital! They said it's a common reaction to Reglan! Why wasn't I warned?!"

• No ...
• January 30, 2022

Metoclopramide for Migraine "I had the most horrendous experience with Reglan for migraine. I’ve never had a migraine bad enough to go to the ER, but I couldn’t kick this one. I wish I was well enough to look up each ingredient before I let them administer the drugs to me. The second I received the Reglan dose, I immediately felt a crushing, awful, crawling-out-of-my-skin weird feeling. I had to pull my mask down and started having a panic attack. Reality felt completely warped. I wanted to pull the IV out, I couldn’t hold still, even though they told me that holding still would make it go away faster: umm, not true. No one told me the potential side effects of this medication. I felt like I was dying, my legs were shaking, I was so restless and hopeless. The nurses kept saying it would go away after a few minutes, of course, it didn’t. After 30 minutes of this nightmare, they finally gave me Ativan for anxiety, and it helped. Stay away from Reglan!"

• Anonymous
• Taken for 1 to 6 months
• December 31, 2021

Metoclopramide for Nausea/Vomiting "I took this drug to combat hyperemesis. Very severe vomiting and nausea during my second pregnancy. My doctors refused to give me anything to treat hyperemesis during my first pregnancy, and they may have been right. I had such severe nausea and vomiting that I was sick all day, every day, and vomited at minimum 10 times a day. So when I went to the ER and was given IV fluids, Zofran, and a prescription for Reglan, I thought it was a cure. Little did I know the toll it would take on my mental health: racing thoughts. I tried stopping Reglan one month after beginning it and was okay for a few days, but the nausea came back with a vengeance. I started taking it again but just couldn’t shake the feeling of being unwell and depression. So I finally stopped taking it after about 4 months on the medication. It’s only been a few days, but I’m depressed and still not feeling 100 percent. There is no winning. If I don’t eat, I hurt my baby, and if I take this medicine, I have another hurt."

• Anonymous
• Taken for 1 to 2 years
• September 7, 2021

For Nausea/Vomiting "Metoclopramide is the worst medication I have ever been given. I was given metoclopramide twice daily, along with cyclizine and ondansetron, for vomiting 2016-17. Due to the severity of my vomiting, the side effects weren't noticed straight away by myself or family. The hospital didn't notice for over a year! This medication, from this little I can remember, made me dribble uncontrollably. I was unable to talk but would scream in pain. Depression crept in and I became paranoid about anything medical. A nurse finally noticed my reaction in 2017, over a year later, after walking back into my room 10 minutes after giving me my medication. I was given this every time I was admitted over 2016-2017. Would NOT recommend this medication to anyone, EVER. I take the other antiemetics daily, with no issues to manage my symptoms."

• Jes...
• April 10, 2009

Metoclopramide for Gastroparesis "Didn't help with nausea, greatly intensified anger and depression."

• Anonymous
• January 31, 2010

Metoclopramide for Nausea/Vomiting "I couldn't eat, sleep, caused hallucinations, nervousness, unsteadiness while walking, urinary retention, and depression."

• Anonymous
• September 14, 2009

Metoclopramide for GERD "I became extremely fatigued, depressed, and lost my appetite. While it slightly cut back on my vomiting, I would not recommend this medicine."

• arj...
• December 22, 2016

Metoclopramide for Nausea/Vomiting "Had it long back for 6 months, 1/2 tab twice a day for stomach infection with other medicine. Realized very late that I was allergic to this medicine. Felt like ending my life. Depressed."

• Vch...
• Taken for less than 1 month
• March 21, 2018

For Nausea/Vomiting "I took this drug in my pregnancy to stop nausea and vomiting. The drug caused depression and dark thoughts. I stopped taking this drug."