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Memantine and Depression: What Users Say

Brand names: Namenda, Namenda XR

Depression: mentioned by 3 users (2.8%)

Based on user experiences from 108 Memantine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

confusion 13.0%
dizziness 11.1%
hallucinations 6.5%
anger 4.6%
anxiety 3.7%
headaches 3.7%
tiredness 3.7%
depression 2.8%
irritability 2.8%
nausea 2.8%

Reviews for Memantine

Showing 3 reviews tagged with "depression". Clear filters to view all 108 reviews.
Commonly mentioned side effects
  • dau...
  • January 16, 2012

Memantine for Alzheimer's Disease "My mother has been treated with the Exelon (patch) for two years now. Last month she was changed to Namenda. She has become irritable, aggressive/depressed and more confused than before. We are asking the doctor to switch back to Exelon."

2 / 10
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150 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • March 1, 2017

For Alzheimer's Disease "My husband has vascular dementia for approx. 4+ yrs. Has been on memantine for almost a yr., no changes for the good, we expected that mostly, but he's more depressed, talks about wanting to die, cannot feel when he has to pee and just wets himself, more unstable walking. I understand this could be a result of the dementia. So everything is impossible to judge. Thank you all for not giving up and for continuing to look for solutions! God bless you all, and help you find a cure. Thanks for your time..... Pat"

1 / 10
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49 Report
  • cls...
  • Taken for 1 to 6 months
  • November 24, 2014

Memantine "My mother is on a dose of 21 mg Namenda XR, and I think it is making her symptoms worse. She is very medication-sensitive, and I see her CHI as more depressed, forgetful, worrisome, and confused. I will be discussing, as always, with her doctor, but I feel she needs to be removed from this medicine. Plus, on a side note, it is nearly impossible to get this medicine, although that has nothing to do with her taking the medication."

3 / 10
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32 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.