Skip to main content

Deplin User Reviews & Ratings (Page 5)

Deplin has an average rating of 7.7 out of 10 from a total of 114 reviews on Drugs.com. 70% of reviewers reported a positive experience, while 16% reported a negative experience.

Reviews for Deplin

Commonly mentioned side effects
  • RAO...
  • Taken for 6 months to 1 year
  • February 27, 2017

For Folate Deficiency "After a surprise DNA test done by my primary care doctor, I received a call from the distributor of this so-called vitamin, and the caller tried to pressure me into auto shipments of prescription before I ever received my DNA results from my doctor. My doctor had shared my DNA results with the makers of Deplin before sharing them with me. Deplin 15 caused extreme bloating and pain twice, resulting in cracked ribs, sternum, etc. I now suffer from shallow breathing and have a lump in my chest where my sternum bone broke, with damage to my rib cage and struggle to breathe deeply, though my lungs are clear. My O2 levels have dropped 5% over the past year, and I was fired by my doctor that caused this when I refused to keep taking it. Kickbacks?"

1 / 10
Was this helpful?YesNo
36 Report
  • TZT...
  • Taken for 1 to 2 years
  • April 9, 2018

For Depression "If you are taking Deplin because of the MTHFR genetic abnormality, you were misled by your doctor(s). This genetic test is being pushed by the psych field even though it has not been proven. Look up the studies on MTHFR and you will soon learn that most of what you read about are myths. That being said, Deplin does have its benefits."

6 / 10
Was this helpful?YesNo
25 Report
  • Mwi...
  • Taken for 1 to 6 months
  • August 17, 2018

For Depression "Holy moly Deplin has changed my life. I took SSRIs that kind of worked but not totally. Started taking Deplin and it has just given me the rest of my life back."

10 / 10
Was this helpful?YesNo
77 Report
  • Anonymous
  • September 17, 2009

For Depression "No side effects, many more plus/up days than before. Seems the longer I am on the Deplin in conjunction with my antidepressant, the better my moods and overall feeling gets."

10 / 10
Was this helpful?YesNo
127 Report
  • Sco...
  • Taken for 2 to 5 years
  • June 13, 2019

For Depression "I have been taking Deplin 15 mg daily as a supplement to other drugs for my bipolar illness. It works well, and I have no noticeable side effects from it."

10 / 10
Was this helpful?YesNo
59 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Sto...
  • Taken for 1 to 6 months
  • July 29, 2016

For Depression "It has helped me quite a bit, although it doesn't seem to have antidepressant effects. It's definitely helping me think better - I'm not confused anymore."

8 / 10
Was this helpful?YesNo
66 Report
  • Anonymous
  • July 28, 2009

For Depression "This has helped better than anything else I have tried."

10 / 10
Was this helpful?YesNo
92 Report
  • Lor...
  • Taken for 1 to 2 years
  • October 29, 2019

For Depression "Taken Deplin for MDD for nearly 2 years and no change in my depression. I recently stopped taking it to save money."

1 / 10
Was this helpful?YesNo
31 Report
  • JSa...
  • Taken for 1 to 6 months
  • July 2, 2019

For Depression "The medicine, after two weeks, I felt disoriented, confused, and flat, definitely not any help, more of a deterrent."

1 / 10
Was this helpful?YesNo
26 Report
  • Tre...
  • Taken for 1 to 6 months
  • March 4, 2019

For Depression "We observed no positive contributions to my treatment of depression. No effect at all. Deeply disappointed."

1 / 10
Was this helpful?YesNo
27 Report
  • Ric...
  • Taken for 6 months to 1 year
  • July 21, 2016

For Depression "Long history of medication-resistant recurrent major depression. Tried Deplin 15 mg daily for 6 months. No improvement at all seen with Deplin. Total waste of money for me."

1 / 10
Was this helpful?YesNo
34 Report
  • mik...
  • Taken for 1 to 6 months
  • May 25, 2016

For Depression "Not worked for my depression. Zero effect."

1 / 10
Was this helpful?YesNo
18 Report
  • Cou...
  • Taken for 2 to 5 years
  • June 27, 2017

For Depression "Started taking Deplin to curb the side effects I was feeling on Lexapro. I'm not really sure if it was working or if I just thought it was working. It also cost a lot of money."

7 / 10
Was this helpful?YesNo
17 Report
  • joy...
  • Taken for less than 1 month
  • April 19, 2016

For Depression "I'm just starting Deplin. I need energy. I've been taking Wellbutrin for two years now, 100 mg, 3 times daily. I pray it works for my energy level."

7 / 10
Was this helpful?YesNo
17 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.