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Avonex and Tiredness: What Users Say

Tiredness: mentioned by 4 users (8.7%)

Based on user experiences from 46 Avonex reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

flu-like symptoms 32.6%
headaches 15.2%
chills 13.0%
body aches 8.7%
tiredness 8.7%
insomnia 6.5%
muscle pain 6.5%
pain 6.5%

Reviews for Avonex

Showing 4 reviews tagged with "tiredness". Clear filters to view all 46 reviews.
Commonly mentioned side effects
  • Nur...
  • Taken for 5 to 10 years
  • March 29, 2014

For Multiple Sclerosis "I have been on Avonex for about 5 years and have had no relapses. Have had Multiple Sclerosis for 14 years. Great to have 1 injection a week rather than 3 with Rebif, which I was on before or Copaxone every day. The only drawback is the headache and tiredness felt the day after. These symptoms have not improved at all for 5 years. Starting to have spasm attacks at night recently, so might change to another medicine. Very effective medicine, though, never had any relapses, and that's the most important thing!"

9 / 10
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31 Report
  • chi...
  • March 25, 2010

For Multiple Sclerosis "I have had MS for over 25 years now and have been on Avonex for about 2 months. I find the shots to be tolerable (given to me by someone else), and the side effects are not too horrible. About 6 hours after injection, I have chills, muscle and joint aches, and a slight headache. These effects last for approx. 4 hours. The following day, I feel tired but okay. Not sure if it is helping. I hope so... time will tell. After all is said and done, the shots and the side effects are not so bad."

5 / 10
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13 Report
  • msg...
  • November 15, 2008

For Multiple Sclerosis "I have used Avonex for about a month now to treat my MS. I have a mild case, and symptoms are not too severe. I appreciate the once-a-week injection (hate needles) but am feeling the side effects. I use Tylenol PM when I take the injections, and that does seem to help. We take the injections on Thursday, and I am able to work from home on Fridays. I am very tired, but usually better by Saturday. I definitely recommend this based on the once-a-week injection vs. the daily or every-other-day injection of the other choices for MS. Good luck."

9 / 10
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15 Report

Frequently asked questions

  • Car...
  • Taken for 5 to 10 years
  • September 11, 2021

For Multiple Sclerosis "Not a lover of injections, but once a week I will persevere. It’s been about five years since I had a flare-up. It’s just the psychological thought of the IM injection, which truthfully doesn’t really hurt. I will continue with this as it’s working, and I am taking my injection on Saturday night. The following day, I am very tired, but it’s Sunday, so a day to relax!"

10 / 10
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4 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.