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Avonex and Insomnia: What Users Say

Insomnia: mentioned by 3 users (6.5%)

Based on user experiences from 46 Avonex reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

flu-like symptoms 32.6%
headaches 15.2%
chills 13.0%
body aches 8.7%
tiredness 8.7%
insomnia 6.5%
muscle pain 6.5%
pain 6.5%

Reviews for Avonex

Commonly mentioned side effects
  • Eug...
  • Taken for 5 to 10 years
  • December 17, 2012

For Multiple Sclerosis "I started Avonex about 6 months after diagnosis. I got terribly sick after injecting. It was like coming down with the flu once a week. I felt feverish and painfully achy. I took naproxen, and that helped. Later on, I asked my neurologist for Vicodin to help out with the achy pain. Together, the medicines helped the side effects. I never miss a week, and as I injected more and more, the side effects have lessened to the point that with Vicodin I can work well on my injection days. I cannot sleep through the night on an injection. I sleep poorly and wake up in pain several times. I have not had a relapse in five years on Avonex, though my balance and leg have slowly worsened somewhat. I still work my feet full time."

9 / 10
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28 Report
  • Jen...
  • February 21, 2018

For Multiple Sclerosis "I have been on Avonex since August 2017, had flu-like symptoms after injecting, but they went away after 24 hours. Now, 7 months later, feeling anxious, sleepless nights, dizzy spells, weakness, and unstable when walking. Anyone else had this experience? I am not sure if it's medicine-related or not, but can't help thinking it is. Thinking about changing my meds, but don't think I could inject more than once a week."

3 / 10
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14 Report
  • Mar...
  • June 17, 2011

For Multiple Sclerosis "I have been on Avonex for 1 month. I chose it due to the injections once a week. I do not even feel the needle or medication go in. I do ice the area well for 3 minutes and make sure the alcohol dries completely before injecting with the smaller needle. Each week the side effects have been easier, but they are still quite strong. I do sleep 8 hours after the injection but wake feeling like I did not sleep at all and like I was run over by a truck until about 20 hours after the injection. It has taken 3 days to get my energy back so far. However, I do notice that my Multiple Sclerosis symptoms have improved, and I have had feeling in my left foot for the first time since my first attack 3 months ago, so that makes it worth sticking with for now."

6 / 10
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13 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.