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Imbruvica and Tiredness: What Users Say

Tiredness: mentioned by 3 users (4.5%)

Based on user experiences from 66 Imbruvica reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

diarrhea 13.6%
fatigue 7.6%
heart palpitations 7.6%
high blood pressure 6.1%
back pain 4.5%
mouth sores 4.5%
nerve pain 4.5%
shortness of breath 4.5%
swelling 4.5%
tiredness 4.5%

Reviews for Imbruvica

  • SST...
  • Taken for 5 to 10 years
  • April 12, 2025

For Chronic Lymphocytic Leukemia "Been using Imbruvica 5 years has brought white count down from 206.3 K/µl in 2021 to 8.0 K/µl in 2024 at 420 mg daily. Feel good overall. I did about 3 months of first taking the Rx, start getting mouth and skin sores, Purpura I was told, more of a blood blister to me. Was given 800 mg of an antiviral called Acyclovir, which helps. Still get a few, nothing as before. My CBC tests are within limits, with only one item slightly over max at 15.1% vs [11.>15%]. Feel pretty good, little tired, have other old age >70+ issues, sometimes hard to say what's the cause of my discomfort."

10 / 10
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  • pat...
  • Taken for 2 to 5 years
  • April 29, 2023

For Non-Hodgkin's Lymphoma "I developed afib, high blood pressure, dizziness, tiredness, and slightly blurred eyesight. I can only take 1/4 dose as I had an allergic reaction to the full dose. It appears to have slowed the progression of the lymphoma. I depend on the Pan Foundation or Johnson and Johnson to help with the price of the medication, as I also have infusions every 8 weeks at $963."

8 / 10
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  • rcp...
  • Taken for 2 to 5 years
  • July 15, 2024

For Chronic Lymphocytic Leukemia "I took it when I was first diagnosed with CLL in 2014. It was the third medication I tried, and it worked very well for me 10 years ago. I was in remission from 2018 till 2023 when my CLL became active again. I tried various new meds that did not work well. Therefore, I asked my doctor to try Imbruvica again. I took it for 4 months, and it stabilized me. Then, I started having neuropathy all over my body, especially my feet and legs. It hurt to walk on my feet, and my legs felt very painful and heavy. My doctor took me off it again in May 2024. Then I began night sweats and felt very tired all the time. He put me back on it, and I broke out in boils. So I stopped taking it as of July 2024. I guess it no longer will work well for me. But in the beginning, it saved my life!"

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.