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User Reviews for Mucinex D to treat Cough and Nasal Congestion

Mucinex D has an average rating of 6.2 out of 10 from a total of 195 ratings for the treatment of Cough and Nasal Congestion. 48% of reviewers reported a positive effect, while 27% reported a negative effect.

Mucinex D Rating Summary

6.2/10 average rating

195 ratings from 213 user reviews.

Compare all 219 medications used in the treatment of Cough and Nasal Congestion.

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Reviews for Mucinex D

Kagard January 2, 2015

“Took 1 Mucinex DM around 6 PM. My experience is like many here. It worked great on my congestion, but it is midnight and I am wide awake. I found this site searching for "Does Mucinex DM keep you awake?" Yup, it does.”

7 / 10
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cloworm April 23, 2014

“I read the reviews on Mucinex and was a little concerned but I was also desperate. For 2 months I had a thick post nasal drip that would cause me to constantly cough, especially at night. I had to sleep sitting up in my chair in the living room. I was wheezing, runny nose, coughing up tons of mucus or clearing my throat from it. I took one tablet at 8 am and another tablet at 8 pm. OMG I can clearly breathe with no wheezing or congestion or mucus getting in my way. I slept through the night and when I woke up my nasal passages and throat were clear. ”

9 / 10
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Breflex33 · Taken for less than 1 month February 2, 2020

“I have been laying here all night after taking Mucinex D. My brain won’t shut down. I am wide awake. Mucinex D does help with nasal congestion. I do not have the jitters or the racing heart. After reading the other reviews,I know now why I can’t sleep. UGH!”

7 / 10
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Lacie23 · Taken for less than 1 month September 16, 2014

“I took two pills at 3:00 pm, I fell asleep around 10:30 pm and woke up wide awake at 1:00 am! I'm still sneezing and coughing but I'm feeling better than I was before so it works but now I'm wide awake and can fall back asleep and I feel funny like my heart beat is slower. I sure hope this feeling passes!”

8 / 10
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Anonymous · Taken for less than 1 month August 19, 2014

“I have bronchitis was coughing non stop with chest congestion. I bought a package of Mucinex DM, I took one tablet around 10pm fell asleep at midnight woke up at 2am jittery still completely wide awake at 6am, good news is I can breathe clearly I haven't coughed in 8 hours; it works that's why I give it a 9, but this stuff is really powerful, I might be awake another 24 hours.”

9 / 10
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Solo672 February 18, 2014

“It's 2:30 am and I'm wide awake! At the suggestion of my doctor, she said to take Mucinex D ... BIG MISTAKE! I'm definitely breathing perfectly, but I'm jittery and unable to sleep! Mucinex D in the morning, Sinex at night!”

7 / 10
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Pleasantly Surprised · Taken for 2 to 5 years July 3, 2019

“I'm a 37 year old male. I've taken Mucinex D at some point each winter for the last few years; typically to help with a lingering cough/mucus after a nasty head cold. Taken as directed it works well for me, though I do get some of the racing heart/anxious feeling others have reported it does not keep me awake at night. One surprising side effect, is that every time I am on this medicine I become like a porn-star. I can make love to my wife for a solid 45 minutes to an hour before ejaculating. I don't know what particular ingredient in this medicine would cause that, but I've experienced it a handful of times.”

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Frequently asked questions

Clarence j August 24, 2016

“Can't help but laugh reading everyone's responses here.. Yes I guess the mucinex helped my congestion maybe 20% more than if I hadn't taken it... BUT I'm wide awake as my mind is racing like I'm on crack .. Paranoid.. Can't sleep a wink. Never done crack but if I had to guess side effects would be similar.. Bummer . Just another confirmation that all natural and a few days longer is better than watching the sun come up while random paranoia thoughts race through the brain. Wish I read the fine print before I starting dosing”

2 / 10
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ArielL November 17, 2013

“This medicine works great. I took two pills every twelve hours and my congestion and pressure was gone within two days. HOWEVER, DO NOT TAKE THIS AT NIGHT. I am talking little to no sleep...tossing and turning, waking up every 30 minutes, etc. So just take two pills in the morning and it will be all good!”

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Anonymous May 24, 2010

“Took one pill before bed (about 8 pm) and was up, literally all night. Fell asleep the next morning at 9 am. The pill worked great on my sinuses but should have taken it in the morning. The packaging does not detail this side effect very well.”

8 / 10
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JmichGee · Taken for less than 1 month February 9, 2014

“I've been plugged up literally for years and had found no relief until now. I had tried everything from frequently rinsing my sinuses with a neti pot system, to prescriptions such as Nasonex, warm/moist heating pads, other over the counter medicines, etc. At this moment I feel pretty great. I took my first Mucinex D tab yesterday late afternoon and my second one this morning. My nose feels completely clear, the pressure behind my eyes is gone, my head feels normal for once....even my ears feel less plugged and are not clicking and popping nearly as much as usual. I'm surprised I have not had the insomnia and jitters that it seems most others have experienced. No unpleasant side effects so far. I highly recommend this! The relief is worth the $$.”

9 / 10
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Krys · Taken for less than 1 month December 29, 2019

“I was diagnosed with the flu and told to take Tylenol, Tamiflu, Flonase, and Mucinex DM. I ended up just taking the Tamiflu and Mucinex DM around 1:00 PM. It is true that I feel a thousand times better, but I have also been very anxious and it is now 2:56 AM and I am not even close to feeling sleepy, despite not having napped all day.”

10 / 10
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aolani · Taken for 5 to 10 years April 22, 2015

“Whenever I use the 12-hour tabs, it helps almost immediately in satiating my urge to cough and/or does a good job of loosening whatever junk is in my chest. Grateful for that. However, it is now 1:46am -- been eyes-wide awake since 12midnight. I took 1 pill around 3pm, fell asleep nicely by 9pm, but BOOM - now jittery and think I'm going crazy, wondering why I can't fall back asleep. Praying. I will not take this anymore, or will only try to take an a.m. dose & skip the p.m. dose. Glad the mucus is lessening, but so not glad about missing sleep.”

8 / 10
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Mandy · Taken for less than 1 month April 6, 2019

“Calmed that annoying every 30 second cough buttttttt I barely slept a wink! I'm really happy to have relief from the cough so I can't complain to much. No jitters or anxiety - but I'm up at 5 am googling 'does mucinex DM keep u awake" lol it does absolutely keep you up it is the pseudoephedrine ingredient . I wouldn’t recommend the nightly dosage if you want to to sleep at all just in the morning. Had a quite a few hot flashes as well. Kept wanting to turn the airconditioner down lower than ever?”

8 / 10
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SinusSufferer · Taken for less than 1 month April 14, 2013

“I have suffered from allergic rhinitis all my life: dry swollen sinus; sinus pressure; headaches; blurry vision; dizziness; lethargy; all sorts of cognitive problems because of the lack of oxygen to my body and brain due to thicken mucus in my respiratory system; not to mention frequent bacterial infections due to accumulated mucus secretions. I had tried every other medicine under the sun. Mucinex has taken all that away and my quality of life has improved 150%. I strongly recommend Mucinex for those with sinus problems due to allergic rhinitis, or anyone who suffers from sinus any sort of respiratory congestion period.”

10 / 10
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Marley04 · Taken for less than 1 month November 20, 2019

“I was diagnosed with a pneumonia. My doc gave me antibiotics but also told me to take Mucinex D twice a day with the antibiotics. Well, I took my first does at 8pm, it's currently 11:30pm and I'm wide awake. All I want is sleep and I can't, my cough has subsided with random coughs here and there and my congestion is better...but I need sleep to get better. I don't plan to take this tomorrow night....ughhh...I'm miserable The pseudoephdrine is the ingredient that keeps you awake”

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Kmac715 February 29, 2016

“I took mucinex d before bed because by sinuses were congested and I could feel mucus in my lungs making it hard to breathe. Shortly after taking the medication everything loosened up, my nose ran but I could breathe. Unfortunately it's now 6am and I haven't slept a wink and have had a rapid heart rate and anxiety. I have a headache and am too jittery to sleep. I did feel slight nauseous after I took the pill and very dry mouth now.”

4 / 10
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Galatea · Taken for less than 1 month May 9, 2014

“I'm having a very severe nasal congestion from a cold. My normal DayQuil/NyQuil were not helping at all. Tried Sudafed, also did not help. Went to chemist in search of powerful medication and got the highest dosage of Mucinex D at the pharmacist's recommendation. Was warned about possible insomnia so I took 1 pill at 5pm thinking it's still more than 5 hours to bed time and I should be fine. Well, the congestion was gone. But I was up for the next 28 hours straight. The congestion returned after about 15 hours which makes me think the medicines effect must have worn off and I can take a nap. But no. After being up for 28 hours I decided that if I'm not getting any rest I may never get over my cold so I took a sleeping pill.”

3 / 10
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jodioctober January 21, 2014

“I took this medicine (2 pills) at 9 PM. I went up to bed at 10:30 and was not able to sleep all night. I tossed and turned, felt wide awake, and I am now at work. It did clear my sinuses and my severe headache is gone. It also made me feel jittery or like I am experiencing anxiety. I am definitely only going to take this first thing in the morning.”

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k8fearsnoart · Taken for less than 1 month October 10, 2015

“Started taking this a week ago because of terrible congestion in my head and chest along with RX Tessalon Perles. I'd taken something years before with the same ingredients as Mucinex that helped immensely and thought that the money was worth it. I've been on it a week, every twelve hours, and haven't been able to sleep more than five hours a night (about 4am after taking it at midnight until 9 am.) I still have terrible congestion with heavy thick mucus. Just finally realized about thirty minutes ago that the Mucinex is the only change. I can't rest AND with the added jitters and insomnia I feel worse than before. I wish I hadn't taken it to begin with.”

1 / 10
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maddie · Taken for less than 1 month February 8, 2020

“Thankful I found this site to calm my nerves. I took mucinex D around 11 pm and fell asleep for about an hour, woke up to my whole body shaking. Of course, started to think of the worst, so made the shakes worse. Then realized it was apart of the side effects of mucinex D. I will no longer be taking.”

1 / 10
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Ceeceebee December 11, 2014

“I was diagnosed with chronic bronchitis and/or COPD. When I get a cold it usually goes straight to my chest and I end up coughing for days, Liquid Mucinex is the only thing that kept the cold out of my chest! ”

9 / 10
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No longer dying · Taken for less than 1 month April 17, 2015

“I was getting really sick but had to travel for work. My lungs hurt so badly I thought I was going to land myself in the ER. I got off a flight and grabbed some Mucinex at the airport and got to my hotel. I was having such a hard time breathing and was coughing so badly I hadn't slept in nights. I took the mucinex and slept all night long and woke up and got stuff out of my lungs and felt SO much better.”

10 / 10
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Vanessa v93 · Taken for less than 1 month July 24, 2016

“Definitely helped relieve my sinus pressure and loosen up mucous. I did feel nauseous after taking mucinex D. It's 2:18am and I'm still up so I decided to google insomnia and mucinex D.. And here I am. At least my congestion improved.”

7 / 10
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Hinton · Taken for less than 1 month November 20, 2019

“Do not take this at all unless you want to be up and feeling like you are never ever going to sleep again. I was taking DayQuils until my very smart girlfriend offered me a mucinex in the middle of the night. Never ever take this or any other med containing pseudoephdrine whatever you are going through is not worth the anxiety and insomnia. I also threw up as well which tasted exactly like the Mucinex”

2 / 10
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