Enzalutamide User Reviews & Ratings (Page 2)
Brand names: Xtandi
Enzalutamide has an average rating of 7.0 out of 10 from a total of 41 reviews on Drugs.com. 61% of reviewers reported a positive experience, while 24% reported a negative experience.
Reviews for Enzalutamide
- Tri...
- Taken for 1 to 6 months
- July 25, 2017
Enzalutamide for Prostate Cancer "Side effects are too harsh and sickening."
- Dav...
- December 23, 2016
Enzalutamide for Prostate Cancer "Found Xtandi to be a waste of time. Instead of aiding or lowering my PSA, it raised it to 90 from about 15 when starting it. There was severe fatigue and dizziness. Not satisfied."
- Tam...
- February 20, 2021
Enzalutamide for Prostate Cancer "My husband declined after he started this medication and passed away 4 months after he started it. No, I would not recommend it."
Frequently asked questions
- Is Xtandi a chemotherapy drug and how does it work?
- Does Xtandi lower prostate-specific antigen (PSA)?
- What is Xtandi (enzalutamide) used for?
- Ano...
- Taken for 2 to 5 years
- August 13, 2026
Enzalutamide for Prostate Cancer "5 years since I started taking Xtandi, so far so good, cancer is sleeping."
- jbr...
- Taken for 1 to 6 months
- March 10, 2026
Enzalutamide for Prostate Cancer "Fatigued, restless legs, hot flashes, spacey feeling in my head. 160 mg daily (4 pills a day). Fatigue being the worst right now."
- enz...
- Taken for 1 to 2 years
- April 16, 2026
Enzalutamide for Prostate Cancer "So far, I have used 15 packages of Xtandi, and so far everything is normal, I don't feel any side effects."
- LC1...
- Taken for 6 months to 1 year
- April 25, 2026
Enzalutamide for Prostate Cancer "Have had no problems taking Xtandi. I take it with Orgovyx."
- Ern...
- Taken for 1 to 6 months
- October 8, 2026
Enzalutamide for Prostate Cancer "Hot flashes and less appetite, and also headaches, blurry eyes and body pains, sleeplessness."
- Ano...
- Taken for 1 to 2 years
- September 26, 2026
Enzalutamide for Prostate Cancer "On very low dose. Have lower respiratory lung build up of mucus. Pain in stomach area. Works very good in lowering PSA and has just about eliminated the cancer."
- Zep...
- Taken for 2 to 5 years
- August 12, 2026
Enzalutamide for Prostate Cancer "Xtandi combined with some relatively modest dietary changes and big attitude changes have now put me in remission from stage 4 cancer diagnosed 28 months ago."
- wil...
- Taken for 1 to 2 years
- July 21, 2026
Enzalutamide for Prostate Cancer "It has lowered my PSA to 0.0006 and stopped the spread to my lymph nodes."
- Ano...
- Taken for 2 to 5 years
- April 1, 2026
Enzalutamide for Prostate Cancer "I have hot flashes and tiredness. It knocks my PSA down, so I am able to get off pills for a while. When PSA rises again, I get back on the pills."
- Max...
- Taken for 6 months to 1 year
- March 26, 2026
For Prostate Cancer "Enzalutamide is easy to take and in my case has been successful in suppressing my prostate cancer so that after chemo and radiation drove PSA levels to be extremely low."
- Pet...
- Taken for 2 to 5 years
- July 1, 2026
For Prostate Cancer "Severe joint pain at 160 mg. Had to reduce it to 80 mg so I could function."
- Geo...
- Taken for 1 to 2 years
- July 1, 2026
For Prostate Cancer "Has worked for me over the past 2 years - a minor weight issue, slower than normal, but OK."
See also:
More about enzalutamide
- Check interactions
- Compare alternatives
- Reviews (41)
- Side effects
- Dosage information
- During pregnancy
- Drug class: antiandrogens
- En español

Enzalutamide for Prostate Cancer "Been on Xtandi a month thus far. Prostate was removed in 2020. It came back in 2021 because Dr. didn't test lymph nodes. Did radiation 45 treatments. After 3 years it returned again. Now on Xtandi. In one month my PSA is non-detectable already, and it was .28 a month ago. I'm very thankful. Not really any side effects other than rising BP, but we've adjusted my medicines to combat that. I highly recommend it thus far."