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Comtan User Reviews & Ratings

Comtan has an average rating of 5.4 out of 10 from a total of 7 reviews on Drugs.com. 57% of reviewers reported a positive experience, while 43% reported a negative experience.

Condition Avg. Rating Reviews Compare
Parkinson's Disease
4.7
 6 reviews for Parkinson's Disease 55 medications

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  • Arn...
  • Taken for 6 months to 1 year
  • February 16, 2020

For Parkinson's Disease "Sinemet 25/100, 6 x daily, 1 tab with 100 mg Comtan, 6 x daily with my Sinemet. Not working well. Off times between medication, 1.5 to 2 hours, off times x 6 daily between medication. Experience bad nightmares, nauseous, involuntary movements, muscle pain, stiffness, difficulty breathing, weak, low concentration span. Cannot see any positive results taking this medication."

1 / 10
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30 Report
  • mjb...
  • Taken for less than 1 month
  • June 17, 2017

For Parkinson's Disease "Didn't improve any symptoms. Side effects: 1. It was messing up my stomach and starting to cause problems with my acid reflux. 2. I had several episodes of feeling really anxious, and my heart would race – on the verge of a panic attack, maybe? 3. Very slight fear of the dark."

1 / 10
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24 Report
  • Sta...
  • Taken for less than 1 month
  • April 11, 2017

For Parkinson's Disease "I just started taking this drug about 3 weeks ago. The first week was a little rough, and it leaves a funny taste in my mouth. However, now that I am getting used to it, I find it helpful. I can take less Carbidopa/Levodopa and have a much smoother transition between the end/beginning of medication times. ONE THING I HAVE FOUND is the importance of staying hydrated. Dehydration is a side effect, and it shows. If I don't watch it, I start feeling bad, and symptoms flare up. After I drink a large glass of water, I start feeling better."

8 / 10
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20 Report

Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • October 11, 2021

"Comtan worked well on my restless leg syndrome. I didn't have to get up in the middle of the night to go to the bathroom, and I was able to sleep for seven hours straight. I never can do that with generic Sinemet because it wears off too soon. I wish I could get a prescription for it instead of just the samples given to me by a neurologist."

10 / 10
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2 Report
  • Anonymous
  • June 8, 2010

For Parkinson's Disease "Terrible hallucinations!"

1 / 10
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29 Report

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  • Bmp...
  • April 11, 2012

For Parkinson's Disease "I take Sinemet 25/100 4 times daily, 1 1/2 tabs, with 100 mg Comtan, 4 times daily, with my Sinemet, and it seems to work well for lessening my 'wear-off' periods, but it does cost a lot."

8 / 10
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26 Report
  • Shi...
  • April 28, 2008

For Parkinson's Disease "The medication is very good. Unfortunately, it is expensive."

9 / 10
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25 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.