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Dextromethorphan / guaifenesin and Nausea: What Users Say

Brand names: Mucinex DM, Mucinex DM Maximum Strength, Tussin DM, Guaifenesin DM, Chest Congestion Relief DM, Mucus Relief DM, Creo-Terpin, Mucinex Children's Cough, Safetussin DM, Robafen DM, Zyncof, Humibid CS, Benylin Expectorant, Cough Formula-DM, Guaiasorb Cough Medicine, Diabetic Tuss DM, Mucinex Fast-Max DM Max, Siltussin DM, Mucosa DM, Tusnel Diabetic, Double-Tussin DM, Amibid DM, G-Zyncof, Guaifenex DM, Fenex-DM, Mucinex Cough & Chest Congestion, Bidex-DMI, Vicks DayQuil Mucus Control DM, GG-DM SR, Humigen DM, Altarussin DM, Guiat Clear DM, Bidex-DM, Vicks Formula 44 Custom Care Chesty Cough, Scot-Tussin Senior, Pecgen DMX, Duratuss DM, Guiatuss Clear, Allfen DM, PediaCare Cough & Congestion, Mucinex Children's FreeFrom Cough & Mucus, HT Tuss DM, Hydro-Tuss DM, Alka-Seltzer Plus Maximum Strength Cough & Chest Congestion PowerFast Fizz, Drituss DM, Guaifen DM, Broncotron, Rompe Pecho DM, Biospec DMX, Delsym Cough+ Chest Congestion DM, Delsym Children’s Cough+ Chest Congestion DM, Guai-Dex, Guaifenesin DM SR, Bidex-A, Robitussin Children' s Cough & Chest Congestion DM, Extuss LA, ExeFen-DM, Coricidin HBP Chest Congestion & Cough, Siltussin DM DAS Cough Formula, Phlemex, DuraDEX, Aquatab DM, DuraDEX Forte, Robitussin Cough + Chest Congestion DM, Robitussin Cough + Chest Congestion Sugar-Free DM, Guaifen DM NR, Guiadrine DX, Balminil DM + Expectorant Sugar Free, Biocotron, Vicks Nature Fusion Cough & Chest Congestion, G Bid DM, Atuss-12 DX, G-Tron, Guaibid DM, Robitussin Cough + Chest Congestion DM Maximum Strength Cofex-DM Congesta DM Alka-Seltzer Plus Maximum Strength Cough & Mucus DM Siltussin-DM DAS-NA Siltussin-DM DAS-NA Maximum Strength Duratuss DM 12 Refenesen Chest Congestion Relief DM Brontuss Tussi-Organidin-DM Coricidin HBP Multi-Symptom Cold (Day) Triaminic Cough & Congestion Dex-Tuss DM Fenesin DM IR Tussin DM Max Vicks DayQuil Cough & Congestion Mucus Relief Cough Gani-Tuss-DM NR Guiadrine DM Diabetic Tussin Cough and Chest Congestion DM Fenesin DM Humibid DM Pediatric Ambi 1000/55 Giltuss Honey Cough & Chest Congestion Giltuss HBP Cough & Chest Congestion Guiatussin-DM Giltuss Diabetic Cough & Cold Giltuss Children's Honey Cough & Chest Congestion Guiatuss DM Giltuss Children's Cough & Chest Congestion Duraganidin Genatuss DM Glycotuss-DM Vicks Pediatric Formula 44e Cough & Chest Congestion Relief Guiacough DM Anti-Tuss DM Aquabid DM GG/DM …show all brand names

Nausea: mentioned by 4 users (9.5%)

Based on user experiences from 42 Dextromethorphan / guaifenesin reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

increased heart rate 14.3%
anxiety 9.5%
nausea 9.5%

Reviews for Dextromethorphan / guaifenesin

Commonly mentioned side effects
  • Anx...
  • Taken for less than 1 month
  • December 12, 2019

For Expectoration "Took an off-brand Mucinex around 10:00 pm, (same ingredients). I fell asleep and woke up at 2:00 am with extreme anxiety, dizziness, rapid heart rate, diarrhea, nausea, dry mouth, and shakiness. Will never take this medication or anything like it again. I'm glad I only took one tablet."

2 / 10
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4 Report
  • Nic...
  • Taken for less than 1 month
  • May 29, 2023

Dextromethorphan / guaifenesin for Cough "I have a cold with a cough, some post-nasal drip, and congestion. I took this before bed, hoping to calm the cough and get some of the stuck mucus out of my chest. It did help me suppress the cough, but also made me wake up at 4 am with a panic attack. Fingers tingling, face numb, heart beating crazy fast, and feeling nauseous and dizzy. Unable to fall back asleep. I have had a similar reaction with dextromethorphan before, but not since I was a kid. I don't recommend taking this if you have adverse reactions to sleep medicines or other sedating medications. I often have the opposite effect with those meds, and this was no different."

3 / 10
Was this helpful?YesNo
2 Report
  • dbe...
  • Taken for less than 1 month
  • September 14, 2022

Dextromethorphan / guaifenesin for Cough "I purchased a bottle of Mucinex DM. Took one cap as directed every 4 hours. After the third dose, the headaches got very bad. My heart rate was very elevated. I could not eat as I would throw up anything I ate."

1 / 10
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2 Report
  • Col...
  • December 4, 2017

Dextromethorphan / guaifenesin for Expectoration "Taste was terrible and gave me a really bad aftertaste that I couldn't get rid of. It also made me really nauseous. I would not use it again."

2 / 10
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3 Report

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