Conjugated estrogens for Oophorectomy User Reviews

• hap...
• August 28, 2011

"Had oophorectomy 8 years ago. On the second week, I started to have terrible hot flashes, couldn't sleep anymore. The doctor started me on all you can name before trying Premarin. Since taking Premarin, I got my life back. Several times, the doctor tried to decrease the dose and wean it off completely. I went into deep depression, crying all the time, and back to the nightmare again. Thanks to Premarin, I feel like a normal human being again. As a floor nurse on a cardiac floor, I have talked to several ladies in their seventies still taking Premarin daily. My actual dose for years has been 0.65 mg daily."

• jas...
• December 31, 2008

"I have been taking Premarin for (the better part of) 25 years. Due to insurance changes through this time, I've been directed to use other estrogens. I will emphatically state that there is NO substitute for Premarin. The others gave me breakthrough hot flashes and PMS. With all of the plumbing gone, these were not acceptable being 32 years old. Premarin every day has kept me at a steady keel with no wavering in mood or temperament."

• Che...
• Taken for 10 years or more
• December 23, 2015

"After a full hysterectomy in 2000 with both ovaries removed, I was given Premarin straight after surgery. My doctor now refuses to continue the treatment, and her colleagues will not prescribe as I am her patient. Now 3 months without and horrendous problems with lack of energy, emotional outbursts, hot flushes, and vaginal skin tearing. The doctor still refuses because of cancer risk. I thought that would be my choice: for better quality of life. What to do? Flew to Malaysia and bought OTC. Life is getting back to normal now. Only side effect may be the slight bloating, but I'm careful what I eat and drink to reduce this."

• Jam...
• Taken for 10 years or more
• January 12, 2025

"I began menstruating at age 14, suffered severe PMS 2 weeks per month, and had severe pain for several days during each period. Age 30, miserable most days, uterus and ovaries removed. Given Premarin & told to never go off. PMS and pain gone forever! Dose gradually reduced & I’m doing fine. 80, taking the lowest dose, .3 mg. Through the years, I tried to go off of Premarin several times & suffered severe hot flashes, fatigue, PMS, and depression. Without Premarin, I do not have a life worth living because I’m sick almost every day & can’t function. I know taking Premarin may cause cancer. Tell your doctor to please give you good information about the cancer risks and a choice to keep taking it or not. I choose to not be sick all of the time vs. the tiny chance of cancer. In my opinion, physicians who refuse to prescribe Premarin under certain circumstances are not listening or don’t care enough. I’ll always choose a physician who can hear & help me."

• Lin...
• Taken for 10 years or more
• May 8, 2018

"I took Premarin 0.625 following an oophorectomy at 36. At 58, I was advised to come off it, as I was past the age of menopause, but I got really bad atrophic vaginitis. I went back on it for another 7 years and have been off for a year. Doctor now reluctant to write a prescription as I'm 65. Now been given Vagifem but miss my Premarin so much. Anyone take it after 65? Tempted to buy on the Internet but worried that might stop too. No health issues or other medication."

• Meg...
• February 14, 2020

"I took Premarin from the day after my hysterectomy at age 45 until a year ago at age 76. It was trouble-free for me. My doctor finally insisted on changing me from the low-dose pill to the cream. Anyway, my bone density tests show my bones to be 30 years younger than I am, my hair is thick, my skin is 20 years younger than I am, I have never had hot flashes or anything one would think I'd have had. I wish I was still taking it. But I didn't know about the horses/mares."

• Mag...
• May 18, 2013

"I could not make it through one day without Premarin since I had my uterus removed. I take along with 24 mg bio-identical testosterone from Woman's International Pharmacy. Had the surgery in 1973 and suffered for so long, they even told me I had Lyme. I was bitten by a tick, and crazy as it seems, these two hormones cured me. Go figure. I only use 'name brand' Premarin like my mother and aunts used in the '50s when they used to combine Premarin and testosterone in one pill. I used to use that in the '70s and '80s before bio-identical hormone cream."

• Kit...
• Taken for 10 years or more
• October 26, 2019

"Now 73. Partial hysterectomy at 27, symptoms of menopause and thyroid failure at 35, extreme depression and suicidal at 43. Doctor tested estrogen, and it was almost nonexistent. I was on the .625 Premarin dosage for about 15 years (thyroid medication was prescribed during that time also) and then switched to .3 with no problems. I read that it is not usually prescribed after 70 and asked my doctor what to do, afraid of the symptoms coming back. She said many older patients reduce their medication, so at 70, I cut back to 3 tablets of .3 a week and am happy to report that I have had no problems. My EHB covers 80% of the cost. This pill saved my life!"

• Ter...
• Taken for 10 years or more
• May 4, 2020

"I had a complete hysterectomy when I was 46 yrs. old. Went on Premarin tablets immediately. On the advice of my physician, I have tried several times to wean off. Unfortunately, side effects were terrible, so I always went back on until now. I’m now 74 years old. I started weaning off a few weeks ago and am now totally off. Other than a lot of hot flashes for the first week (not bad) and now just a few here and there, I’m doing great. I don’t think it helped my bones, as I have osteoporosis and am taking Risedronate for that."

• JDa...
• October 26, 2019

"Had surgery in 1985 due to endometriosis. Am currently 72. My dosage is 1.25. A month after surgery, I was advised to take HRT 21 days on and 7 off and repeat. That left me with 'PMS' during the 7-day off period. Dr. advised that off time was necessary to avoid estrogen build-up. I decided to take estrogen for 5 days and 2 days off. This has served me well. Through the years, for one reason or another, I would try other products. BUT, I always returned to Premarin: the brand name. The generics I tried were always found wanting. Concerning insurance: while I was employed, the insurance was never a problem. I retired at 55 years old, receiving Social Security Disability. After being disabled for 2 years, one must apply and accept Medicare, changing all coverages and, in my case, lessening them. Medicare Part D has been a godsend for many, but not me."

• son...
• July 16, 2009

"In 1971, I had surgery and was put on 1.25 Premarin and told I must take it for life. Now, in the year 2009, looking back on all, I have to say I wish I had refused the surgery and didn't take Premarin. They didn't tell us about the possible side effects in those days, told only we wouldn't understand. I reported side effects to doctors, who did nothing. My huge stomach is finally beginning to shrink after being off Premarin for years."

• Tan...
• Taken for 6 months to 1 year
• February 3, 2022

"Unnecessary oophorectomy performed 2000, age 50, still having periods. Hysterectomy too, due to fibroids. Now discover that it's possible to remove fibroids, leaving womb intact! Suffering terribly from symptoms, given 1 mg of Premarin. Over three years, I started with severe headaches resulting in projectile vomiting! I was working at the time, so came off it entirely. No good! I tried different drugs, given Climaval, fantastic! Felt driven, confident, marvelous. Hair and skin glowing again. So, MHRA in the UK removed this drug from the market. I tried many more, I am placed on Premarin 0.3, which makes me feel nauseous, appetite affected as a result, and have arthritic pain. However, I stick it out as, mentally, I don’t feel too bad. The sickness fades, I am now stuck with bloating, flatulence, which is noisy and uncontrollable. Why aren’t side effects removed from these drugs?"

• hys...
• Taken for 10 years or more
• May 9, 2013

"Premarin is great for reduction of discomforts caused by surgical menopause, hair, skin, sense of well-being, sleep, moods, and energy levels."

• Anonymous
• September 18, 2008

"I've taken Premarin for over 17 years. It is great for controlling menopausal symptoms and mood swings in early surgical menopausal patients. It is also supposed to help prevent osteoporosis."

• 200...
• Taken for 2 to 5 years
• December 28, 2016

"This medicine is exceptional! I have not had any hot flashes or moodiness - and I sleep well."