Nexletol for High Cholesterol User Reviews

• Ann...
• Taken for 6 months to 1 year
• July 13, 2024

"After trying everything on the market to lower my cholesterol, and experiencing terrible side effects from statins, I read about Bempedoic Acid. I was already taking Zetia with no results. I asked my cardiologist about this new drug, Nexletol, and he agreed to let me try it. In three months, my total cholesterol went from 255 to 126 and no side effects! It worked for me when everything else did not."

• Sus...
• Taken for 1 to 6 months
• November 3, 2024

"I'm 65 and have suffered from high cholesterol since my 20s. I tried statins, but they caused a rotator cuff tear with type 2 SLAP tears. I was a little hesitant to start Nexletol based upon possible tendon rupture. I've been taking the drug for 2 months now and am thrilled with the results. No side effects, and my blood test showed my cholesterol level, for the first time in 46 years, is normal."

• Hur...
• Taken for 1 to 2 years
• July 8, 2024

"After taking Nexletol for 1 1/2 years, I developed severe peripheral nerve pain in my arms, shoulders, legs, and feet. I had severe burning pain. After stopping Nexletol, the burning in my shoulders started to lessen after 3 days and quickly stopped. However, the stiffness in my back, and the burning nerve pain in my legs and feet has taken over the last 1 1/2 years to get better. It’s been a slow process. (Gabapentin, PT, Tylenol, NSAIDs, and cortisone injections). I am now treating IT Band issues and bursitis. By the way, I had similar peripheral nerve damage from statins previously before taking Nexletol. That nerve pain wasn’t as severe though. On a good note, Nexletol alone decreased my cholesterol greatly."

• Dov...
• Taken for less than 1 month
• July 4, 2025

"I've been taking Nexletol for a little over two weeks. I experienced diarrhea twice after eating nightshades (red peppers and tomatoes), which has never happened to me before. There is no information on whether or not Nexletol can increase nightshade sensitivity. I am wondering if anyone else has suddenly had a change in nightshade sensitivity after taking Nexletol. I hoped I might find something here, with no luck. I don't know yet how Nexletol has affected my cholesterol levels."

• Anonymous
• Taken for 6 months to 1 year
• April 14, 2024

"I am taking Nexletol for high cholesterol. It was the first medication that did not produce dizziness and leg cramping (caused by statin medication). Downside: expensive, occasional leg cramping and chest tightness."

• Ano...
• Taken for less than 1 month
• August 13, 2025

"Started taking 40 mg pravastatin and 10 mg ezetimibe and had to drop pravastatin to 20 mg due to some muscle and joint pain, but afterwards, no noticeable side effects. Have to wait 8-12 weeks for the next blood test to determine how much LDL was reduced. Last LDL before adding Nexletol was 106, so hopeful this combination will get LDL near target levels of < 70. Worried the drop in pravastatin dose might negate adding the Nexletol, so wish me luck!"

• Fan...
• Taken for 6 months to 1 year
• May 1, 2025

"It has caused pain in both of my feet, stiffness in all toes in both feet. Weakness in legs, arms, and shoulders. Elevated my uric acid levels. Taken off it for 1 week to see if these symptoms go away. It did lower my cholesterol."

• Tah...
• Taken for 6 months to 1 year
• September 4, 2024

"Leg pain when I start walking. Drowsiness. Back pain. Frequent urination. Tiredness."

• Jer...
• Taken for 1 to 6 months
• July 9, 2025

"I've been on it for 4 weeks. No side effects. I couldn't take statins anymore, and Repatha also caused pain and constipation."

• Ano...
• Taken for 1 to 6 months
• April 16, 2025

"I am on Nexletol - I get heartburn from ezetimibe. I have no side effects from the Nexletol whatsoever. I started off taking a half tablet and increased to one per day without issue."