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Aluminum chloride hexahydrate topical and Rash: What Users Say

Brand names: Drysol, Hypercare, Certain Dri, B+Drier, Xerac AC

Rash: mentioned by 32 users (5.3%)

Based on user experiences from 603 Aluminum chloride hexahydrate topical reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

itching 33.2%
burning 29.0%
stinging 8.6%
pain 5.6%
rash 5.3%
irritation 4.5%
tingling 2.7%
sweating 2.2%
dry skin 1.3%
redness 1.3%

Reviews for Aluminum chloride hexahydrate topical

Commonly mentioned side effects
  • yos...
  • February 13, 2020

For Hyperhidrosis "On my first night applying Drysol, it felt fine with only a little itching in my armpits. The day, I sweat a little bit but drastically less than normal. The second night applying it, it itched and burned pretty bad to the point where I was tossing and turning for almost an hour. I put Vaseline over it and it just helped enough so that I could fall asleep. That day, I sweat almost nothing with no pit stains or anything. The whole day, I had a rash on my armpits and they just felt irritated though, so I decided not to apply it for a third night. I put deodorant on the next day and didn't sweat a drop. The irritation was also completely gone. I put it on once more and it itched but didn't nearly hurt as bad as the second night. My point is that Drysol has a few downsides, but they don't last and it is so worth it with the impact that it makes on the way you can live. I highly recommend, just get ready for a little itching."

9 / 10
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77 Report
  • Man...
  • Taken for 2 to 5 years
  • March 22, 2020

For Hyperhidrosis "This is the best product I’ve ever used! So glad I found this roaming around Walmart in 9th grade. Before, I had to wear black shirts or sweatshirts to hide my huge sweat stains under my armpits; even so, I would still get noticeable stains. Other types of deodorant seemed to have no effect. It was so embarrassing and ruined my confidence. I was so desperate to hide my sweat stains that I thought about using pads on my clothes or duct taping my armpits. It took a few weeks to kick in. I have used it every night for a few years now, and I use normal deodorant every morning. I no longer have sweat stains, even when wearing skin-tight or gray clothes! So happy that my armpit stains are now a problem of the past! However, it does cause itching, and my armpits developed swollen lymph nodes and rashes a few times. That’s why I only use it at night and don’t shave my armpits often. But overall, the mild itchiness is well worth being able to wear whatever I want to!!!!"

10 / 10
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20 Report
  • Emm...
  • Taken for less than 1 month
  • May 23, 2019

For Hyperhidrosis "I originally was prescribed Drysol over a year ago, but after reading about the side effects (rash, stinging, itching), I was too afraid to use it. Well, after years of dealing with excessive armpit sweat, I decided to give it a try. I bought a lot of black shirts. I'm not going to lie, it definitely stings and itches pretty bad. But it's so, so worth it. After two applications, I went for a hard run, and I was sweating everywhere else from my body EXCEPT my armpits. It's truly a miracle. I can't tell you how freeing it feels to be able to go out in public wearing a yellow shirt with sleeves and not having to worry about sweating. Give it a try!"

9 / 10
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21 Report
  • Mad...
  • April 7, 2019

For Hyperhidrosis "I used to sweat so bad. Dripping sweat from my underarm to my back. Leaving embarrassing sweat stains. I could be freezing cold and sweat crazy. After the first use of Drysol, I saw results the next day, no longer had sweat stains. I’ve only used it 3 times now, and it’s been amazing. I used it 2 nights straight. Now doing every other night. But I do have a bad rash under my arm, which I was told was expected. It does burn and itch a little after application, but it goes away after an hour. APPLY AT NIGHT TIME BEFORE BED. When the sweat glands are working less. But I am in love with this product and have never been so confident."

10 / 10
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  • Anonymous
  • Taken for 10 years or more
  • September 19, 2019

For Hyperhidrosis "I’ve been using Certain Dry for over ten years. I use it a few times a week, but not every day. When I first started using it, I used it daily, which caused a rash, so I cut down to every other day, and I can say I do not sweat under my arms anymore. It’s been ten years free of smelly, sweaty underarms. I tell everyone about this product. It does itch a few minutes after application, but it’s because it’s literally closing your pores. If you can deal with a little itch under your arms for a few minutes, it’s definitely worth the discomfort. This product changed my life. It changed my confidence. I love Certain Dri."

10 / 10
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  • She...
  • Taken for 6 months to 1 year
  • October 24, 2018

For Hyperhidrosis "I used Certain Dri and it was wonderful! I had finally found something that actually worked, even if I wore a sleeveless tank or shirt in the summer. Although I also got the very itchy, burning rash. Terrible rash, and it worked so well I continued to use it. The rash got so bad after a while, I began to notice that it had taken the color and pigmentation from my underarm in the entire area that I applied it. It is now two years later after discontinuing use, and I still have no pigment under my arms in that area. It looks like I was burned and have huge scars under my arms with no color. I am very tan as I have American Indian in my family background, and it looks horrible. I am embarrassed to wear a bathing suit now or sleeveless shirts at all! I am afraid, being it is now two years later and is still the same, it is permanent. :( I have gone back to Mitchum unscented roll-on as I cannot stand the powder smell. It works well but not as good."

5 / 10
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12 Report
  • Bre...
  • June 28, 2016

For Hyperhidrosis "Although Drysol does work, it is also very painful for me. When I apply, and even hours after, I have pain in my armpits. They are completely bumpy with red rashes, and the burning is the worst part. The morning after I apply it, the redness dies down, and so does the pain. The sweating does go away, and this product would be perfect without the horrible side effects it gives me! Overall, I feel that the product is not worth the pain I go through when and after applying."

8 / 10
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13 Report
  • Mad...
  • June 6, 2023

For Hyperhidrosis "I finally was able to use Drysol after years of dealing with excessive sweating. The first night I used it, I felt very mild itching about 40 minutes after application. The next day, I didn’t sweat at all! The following night, I applied the same amount to my underarms and dealt with EXTREME burning and a red rash that lasted hours. Drysol definitely works, but be careful if you have any skin sensitivities or don’t want to deal with the excruciating pain :("

3 / 10
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4 Report
  • chi...
  • Taken for less than 1 month
  • August 23, 2020

For Hyperhidrosis "Ok, so I’ve been suffering with hyperhidrosis for as long as I remember, maybe 8th grade. Well, I’m in my 30s, and I used Drysol for the first time last night. Today, no unnecessary sweating or anxiety about it. Will continue use. Side effects: it burns like anything, and I did have some rashes from it. I’m a Black woman, and this is a game changer for my face and pits!"

10 / 10
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8 Report
  • Sud...
  • March 22, 2019

For Hyperhidrosis "I used to sweat so much. I could stand outside during a Canadian winter in only a T-shirt and still sweat through my shirt. I had problems for as long as I can remember. It got to a point where I began researching Botox treatments or any other extreme measure to stop sweating. A friend of mine recommended Drysol. The first time I tried it, I think I put too much on because it was so itchy, and I got a pretty bad rash. But the next day, just to see, I wore a grey cotton T-shirt, and not one single drop of sweat. I let my pits heal and waited until the rash went away to try again. Using less Drysol, it wasn't nearly as painful. Still a bit itchy though, but I took an anti-inflammatory, and it helped me sleep soundly. I used it every couple of days for a while, and now I use it once every couple of weeks. I never thought I'd find relief, but this stuff is amazing! Just don't put it on after you shave, and make sure your armpits are clean and dry before you put it on. This stuff changed my life!"

10 / 10
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9 Report
  • Anonymous
  • May 13, 2009

For Hyperhidrosis "I've had hyperhidrosis for 15 years. I would embarrassingly sweat through multiple shirts daily. Business meetings were awful. I would actually adhere my wife's menstrual pads to my undershirts to try and get me through the day, but would eventually sweat through those too. In a recent visit to my dermatologist, he prescribed Drysol/Hypercare. Skeptically, I applied it that night. It burned and itched, keeping me up all night. The next day, I was COMPLETELY dry. I applied it again the next night, still itched but not as bad - slight rash. I took the next 3 nights off to let my armpits heal and still no sweat. I'm on my 2nd week, 3rd application and NO SWEAT. Far less irritation now, dry, and couldn't be happier - truly life changing."

10 / 10
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16 Report
  • Anonymous
  • Taken for less than 1 month
  • March 24, 2013

For Hyperhidrosis "I am 19 years old, and I have been so embarrassed by my excessive underarm sweat for as long as I can remember. The worst was when I realized that I would sweat more from my underarms than the guys I hung out with. I tried every 'prescription strength' and 'clinical strength' over-the-counter product that I could find (I even tried men's clinical strength antiperspirant/deodorant), and nothing gave me relief. Finally, I talked to my doctor, and she mentioned Drysol. I have very sensitive skin, and when I had to use it for the first 2-3 days in a row, I had excessive itching and burning, and a rash, but I toughed it out, and now I no longer have the burning or rash. I have been using the product for 2 weeks now, and I couldn't be happier!"

10 / 10
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14 Report
  • meg...
  • June 1, 2013

For Hyperhidrosis "This product is absolutely amazing! I have only been using it for a few weeks, but it is great. I honestly used to always wear black shirts and the same black jacket because I would sweat over nothing, and being active (like walking and physical education) made it worse. I finally had a doctor's appointment and told her about my problem and expected her to say that I would have to get surgery or something, but instead, she prescribed me this. At first, I thought I was hopeless and nothing could help, but I was wrong. It is a MAJOR self-esteem and confidence boost now that I can wear whatever I want. There is just one big problem with this product. I don't know if it happens to other people, but it has given me a major rash, and it's very hard not to itch."

8 / 10
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12 Report
  • C R...
  • Taken for less than 1 month
  • December 3, 2013

For Hyperhidrosis "In first year university, I started sweating so much under my arms that I would have to change my undershirt 5 times a day and only wear dark colors so I wouldn't show my sweat stains. I tried every deodorant and antiperspirant I could find, and nothing worked. I went to the doctor, and he recommended Drysol (no prescription needed). I used it for the first night and covered my underarms with lots of it. It was itchy, and my skin was irritated in the morning with a red rash, but I did not sweat again! The small amount of pain from the rash was worth it. I only have to reapply once every couple of years! Amazing."

10 / 10
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17 Report
  • Gui...
  • Taken for 1 to 2 years
  • February 10, 2013

For Hyperhidrosis "This literally changed my life. I can now wear colorful shirts without worrying about sweat stains. It worked after the first application. My doctor said I'd experience 'mild itching,' and I wish she would've been more truthful and said 'practically unbearable itching,' but the longer I use this medicine, the less I itch. I don't itch at all anymore when I put it on. If I use it daily, I get a dry, painful rash in my underarms, so I use it every other or every 2 days."

10 / 10
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10 Report
  • SN0...
  • Taken for less than 1 month
  • January 6, 2023

For Hyperhidrosis "So I have always struggled with hyperhidrosis, and my dermatologist prescribed this to me. From the outside of the bottle, this looked pretty normal, I did read the instructions. The one thing I did not read was the ingredients list (I do not usually get allergies). I got out of the shower and waited an hour or two to make sure I was fully dry. I put this straight on my armpits, and I felt the worst stinging pain. After a few minutes of trying to frantically wash it off, I had hives all the way down my back, arms, chest, and underarms. The only thing that worked for me to get the hives to calm down was when I washed the affected area off with soap. It’s been two days, and my underarms are still puffy."

2 / 10
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2 Report
  • Anonymous
  • December 9, 2012

For Hyperhidrosis "Armpits would sweat profusely. I would stuff paper towels under my armpits, and they would come out drenched. I used Hypercare for the first time. The sweating completely stopped. However, I broke out in a bad rash under my armpits the first time I applied it. I noticed that my armpits were completely dry within the first week, but the sweating became worse on my hands and feet. I plan on using it for my hands as well."

9 / 10
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5 Report
  • Anonymous
  • Taken for less than 1 month
  • September 15, 2015

For Hyperhidrosis "I've had hyperhidrosis for over 5 years now, on my hands, feet, and underarms. It was honestly so frustrating not being able to wear light t-shirts and growing completely petrified when someone offered to shake my hand. I couldn't even hold my boyfriend's hand! It was miserable. But Drysol is magic and has changed my life. For me, it isn't necessary to apply every night, or my skin burns pretty bad and gets a rash. So usually I will apply it 2 or 3 times a week, and I literally do not sweat one drop on my underarms. I completely recommend Drysol."

9 / 10
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4 Report
  • Thi...
  • Taken for 1 to 6 months
  • May 2, 2013

For Hyperhidrosis "This is absolutely amazing. After about 1 3/4 years of sweating, I finally had enough when I would sweat through hoodies with huge stains. None of my friends would say anything about it, but my mom (who also has it) finally called my pediatrician and got a prescription. I put it on the first night, and it burned a lot, but it's nothing unbearable. The next day, sweat-free. Some days I would forget to put it on at night and go through the day with little to no sweat at all. Not even sweating through my clothes. I still put it on every night just to be safe, but it really works! I would recommend getting this product. Some people say it doesn't protect against smell, but it does for me. The only problem is a little itching during the day and a rash."

10 / 10
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4 Report
  • Aly...
  • Taken for less than 1 month
  • June 7, 2019

For Hyperhidrosis "This product, when used correctly, did not work for me. It plugged my underarms, yes, but then caused me to sweat everywhere else-which, I'm assuming, because my skin wasn't used to sweating, caused me to develop blister-bumps on much of my skin. When (after a week) I realized it was likely this product and stopped, the rash slowly but surely went away. I had tried this years ago, and I guess the ingredients will never change or be less severe."

1 / 10
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6 Report
  • Lif...
  • October 13, 2015

For Hyperhidrosis "I have been using Drysol for 15 years. I have figured out the perfect process for using the product. If you aren't careful, you can apply Drysol in such a way that it will cause extreme burning sensations and rashes. Here's how to apply it properly: Men, carefully shave the center portion of your armpits to expose the bare skin. If you look closely, you'll be able to see the sweat gland areas of your armpits. Apply the product only to this area and not to the surrounding skin. Do this right before bed and sleep all night long with it on your armpits - should keep you dry for 3 to 4 weeks. Do this multiple nights in a row for a longer effect. My dad totally cured his hyperhidrosis by doing this every night for two weeks."

10 / 10
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  • Kik...
  • Taken for less than 1 month
  • December 6, 2021

For Hyperhidrosis "I have had excessive sweating in my underarms for as long as I can remember. I finally decided to do something about it. Before jumping to more invasive options, I was prescribed Drysol. My first application was horrible. My skin burned so bad, and I had a painful rash for days. I was scared to use it again. But I noticed even after one use, my sweating has decreased, which is life-changing. We'll see how it works long-term, but despite the pain I experienced, it may be worth it."

8 / 10
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  • Jac...
  • October 5, 2011

For Hyperhidrosis "Since about 7th grade, I've been dealing with SUPER sweaty armpits. I mean a water fountain. I would have to wear sweaters to school every day (even in summer). I avoided light-colored shirts and anything tight-fitting. I tried men's deodorants and every kind of women's deodorants out there. Finally, at age 19, I went to the doctor and embarrassingly told her of my sweat problem, and she prescribed me Hypercare. My first application itched and burned a little, but the next morning I didn't sweat. Last night was my second application, and this morning it had a little rash (I'm not worried), but I think it's totally worth it if it keeps my sweat problem under control. I should have gone to the doctor in like 8th grade! Thank you, doctors!"

10 / 10
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3 Report
  • Liv...
  • Taken for less than 1 month
  • November 7, 2013

For Hyperhidrosis "Well, I've had excessive sweating for years. I had gone to my doctor and was prescribed Drysol, and within twenty minutes of applying it, my skin broke into an extremely painful, bumpy rash. I followed all the instructions: no shaving before putting it on, just a thin layer, not to rub it in, etc. I'm sure the product works, I just have extremely sensitive skin, so I'll just need to continue looking for a product or medical procedure that works."

3 / 10
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8 Report
  • soc...
  • March 28, 2011

For Hyperhidrosis "I had been suffering from excessive sweating in my armpits for at least 2 years before I finally got a doctor's opinion. Getting this medicine really changed what I did from day to day. I use it just once a week, and I never find myself sweating anymore. Sometimes I feel like I'm sweating, but when I look, I don't have a speck of sweat. The only problem I have with this medicine is that every time I apply it, my armpits get extremely itchy, and sometimes I will wake up with a rash, but I guess that's just the price of not having sweat anymore. I strongly advise you to talk to your doctor about this medicine if you're having the same problem! Don't be scared to ask!"

10 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.