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Drysol and Irritation: What Users Say

Irritation: mentioned by 13 users (4.1%)

Based on user experiences from 320 Drysol reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

itching 32.8%
burning 28.8%
stinging 8.8%
pain 6.3%
rash 5.6%
irritation 4.1%
tingling 2.8%
discomfort 1.9%
dry skin 1.9%
dryness 1.3%

Reviews for Drysol

Commonly mentioned side effects
  • yos...
  • February 13, 2020

For Hyperhidrosis "On my first night applying Drysol, it felt fine with only a little itching in my armpits. The day, I sweat a little bit but drastically less than normal. The second night applying it, it itched and burned pretty bad to the point where I was tossing and turning for almost an hour. I put Vaseline over it and it just helped enough so that I could fall asleep. That day, I sweat almost nothing with no pit stains or anything. The whole day, I had a rash on my armpits and they just felt irritated though, so I decided not to apply it for a third night. I put deodorant on the next day and didn't sweat a drop. The irritation was also completely gone. I put it on once more and it itched but didn't nearly hurt as bad as the second night. My point is that Drysol has a few downsides, but they don't last and it is so worth it with the impact that it makes on the way you can live. I highly recommend, just get ready for a little itching."

9 / 10
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77 Report
  • Abb...
  • Taken for 2 to 5 years
  • February 19, 2015

For Hyperhidrosis "This product works for hyperhidrosis. If you have sweaty hands, this will work. I've been using it for about two years now, and thank God it still works. But lately, for some reason, it's causing irritation between my fingers, but doesn't matter. I will endure it, as long as it stops my hands from sweating."

9 / 10
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24 Report
  • MCG...
  • November 13, 2013

For Hyperhidrosis "I've been using Drysol for close to 6 years now. Prior, I used to sweat just sitting in my chair, and it made me extremely self-conscious. I tried every deodorant/antiperspirant on the market, and nothing helped. Finally, I went to my dermatologist, and he prescribed this. The first few times I used it, it was extremely itchy and red, but I would tough it out. I learned from experience not to shave before applying and to make sure I wear a T-shirt to bed, otherwise, the rubbing together may cause irritation. Over the years, my sweating has seriously reduced. I went from having to put Drysol on every couple of days to weeks, now I put it on MAYBE 3 times a year. Love it."

10 / 10
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18 Report
  • Kin...
  • June 27, 2017

For Hyperhidrosis "I am someone who sweats anytime under my arms, it could be for any reason, and I would filter my life around it. Loose shirts, dark colors, and I would rarely ever raise my arms for the fear that I would show my stains of sweat. Talked to my dermatologist, and they offered me Drysol, and I absolutely loved that I could wear anything and I wouldn't sweat, but it does have its downside to it. I am a girl, and shaving under my arms irritates the crap out of it and burns. I tried to use Nair instead of shaving, and it burns even more. I honestly do not know what to do."

8 / 10
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16 Report
  • It ...
  • March 28, 2016

For Hyperhidrosis "'This product is flat-out amazing.' As a teen, I was always conscious about my sweaty hands. Rejecting people whenever they reached out for a handshake was more than embarrassing, but I still did it, and people would always comment. But when I found Drysol, I didn't think it would work for me and ignored all of the 10 ratings. I gave it a shot though, and it WORKED within the next day I applied it. I experienced no irritation on my hands, but it may be different for other people. This thing does what it says it does, and BELIEVE ME. With consistent use within the first few days, your hands will be bone dry, and you begin to realize that you need to apply it less and less. Thanks to Drysol, I'm literally reborn and anxiety-free."

9 / 10
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13 Report

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  • Yur...
  • January 16, 2020

For Hyperhidrosis "I've been using Drysol for about a year and a half now and got my 2nd refill about a month ago. With my first bottle, there were no complications. The product rolled on nicely, and I didn't sweat at all. With my 2nd bottle, not the same results. The product has caused severe burning and irritation under my arms, and nothing I do stops it. Even using cold water to close the pores."

7 / 10
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5 Report
  • Gir...
  • November 21, 2022

For Hyperhidrosis "I’m in my 40s and have lived with extreme armpit hyperhidrosis since probably puberty. I couldn’t wear any cute shirts. I had to plan my life around sweating armpits, I swear. I couldn’t go anywhere where I’d have to be in a formal dress unless it was sleeveless and was cut lower (and preferably black!). It ruined so much of my life. I was so insecure. I can’t believe I’m just now introduced to this life/game changer. The first few times burn a bit. It really needs to dry, I think. But it’s worth all the irritation. I can wear anything! Life is no sweat. ;) I feel like my armpits do have a slight different odor now, so I’m trying different deodorants to see if it can balance out… maybe it’s the aluminum not meshing with my body. Idk, but I am still over the moon with discovering this."

9 / 10
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2 Report
  • Anonymous
  • Taken for less than 1 month
  • August 29, 2016

For Hyperhidrosis "I read the info sheet that was given to me when I got Drysol. It said some minor burning and irritation was possible. The first night I used it, it burned to the point where, after an hour, I had to wash it off just so I could get to sleep. Even then it burned, but it wasn't unbearable. The next night, same thing. I'm liking the product as it helps, but it isn't worth the pain."

9 / 10
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4 Report
  • Swe...
  • Taken for less than 1 month
  • April 14, 2015

For Hyperhidrosis "I was prescribed Drysol by my dermatologist. I was open to try anything because I deal with hyperhidrosis and bromhidrosis. You can't use any deodorants with this product, so that made me nervous. The first application was fine, but I was smelly the next day as I couldn't use deodorant. Over the course of a few days, it started working more, and I was sweating a lot less. However, the cons are that this product is so irritating! My skin was raw to the point that when I moved my arms, it hurt. You have to apply the solution at bedtime, and it was to the point that I couldn't fall asleep due to the pain of the irritation. And this was after I had stopped doing daily applications and was only applying it every 2 to 3 days. Overall, I wouldn't recommend."

7 / 10
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9 Report
  • Sky...
  • August 24, 2015

For Hyperhidrosis "This works. Simple as that. One use and it works wonders. The only problem I've had was having bad irritation. Itching, burning, and quite painful, tbh. It works, though, if you can get through the pain."

7 / 10
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3 Report
  • Dry...
  • Taken for less than 1 month
  • May 13, 2021

For Hyperhidrosis "This stuff really works, it was a godsend. I told my doctor about my severe sweating. I would always wear dark-colored shirts to cover up the sweating. I used this on Tuesday night, and Wednesday there was no sweating at all, I stayed dry. I put it on again Wednesday and was still dry, there was some irritation. Make sure you follow the directions. We will see how it works in the summer when it gets really hot..."

10 / 10
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1 Report
  • Sch...
  • September 12, 2017

For Hyperhidrosis "I am suffering from the furiously itchy armpits right now after use. I'm hoping it doesn't get worse this time. I know it works, but the irritation has been bad in the past. I last used this 6 years ago when I had shaved right before use and was left with scabs and infected-looking rashes. Luckily, it faded in a few days, but I swore it off after that. Then, a couple of years later, I had a baby and nursed for two years, so obviously, I did not want these chemicals near her face. However, my hyperhidrosis seems to have worsened in the past couple of years. I will sit at an IEP (Individualized Education Program) meeting wearing all black (I am not goth, but I dress like it) and sweating to my elbows. Drysol is the clear retort. The itchiness is misery, but I will wear a colorful top tomorrow!"

8 / 10
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2 Report
  • Gue...
  • Taken for less than 1 month
  • April 20, 2021

For Hyperhidrosis "My doctor prescribed me Drysol a while ago. I used it today, and my arm is super irritated. I'm feeling a lot of discomfort. I've used Neosporin, and it doesn't solve it. I do not recommend it. If I could post a photo to show."

1 / 10
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2 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

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