Generic Name: Sofosbuvir (soe FOS bue vir)
Brand Name: Sovaldi
- You will be tested for hepatitis B before starting sofosbuvir. In people who have had hepatitis B before or carry the virus, the virus has become active again during or after treatment with drugs like this one. This can lead to very bad and sometimes deadly liver problems. People who have hepatitis B and hepatitis C need to be watched closely during and after treatment with sofosbuvir. If you have questions, talk with your doctor.
Uses of Sofosbuvir:
- It is used to treat hepatitis C infection.
What do I need to tell my doctor BEFORE I take Sofosbuvir?
- If you have an allergy to sofosbuvir or any other part of sofosbuvir.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have liver problems other than hepatitis C.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with sofosbuvir, like certain drugs that are used for HIV, infections, or seizures. There are many drugs that must not be taken with sofosbuvir.
- If you are taking St. John's wort. Do not take St. John's wort with sofosbuvir. This medicine may not work as well.
- If you are taking another drug that has the same drug in it.
This is not a list of all drugs or health problems that interact with sofosbuvir.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take sofosbuvir with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Sofosbuvir?
For all patients taking sofosbuvir:
- Tell all of your health care providers that you take sofosbuvir. This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine is used with ribavirin, with or without peginterferon alfa. Talk with the doctor about the risks and side effects that may happen with those drugs.
- It is not known if sofosbuvir stops the spread of diseases like hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
- Slow heartbeat and the need to get a pacemaker have happened when amiodarone was given with sofosbuvir and certain other hepatitis C drugs. Sometimes, this has been deadly. Slow heartbeat has happened up to 2 weeks after starting hepatitis C treatment. You will need to be watched closely if you will be taking amiodarone with hepatitis C treatment. Follow what your doctor has told you to do. Call your doctor right away if you have signs of slow heartbeat like chest pain, confusion, dizziness, passing out or near-passing out, memory problems, shortness of breath, tiredness, or weakness.
- If you are taking warfarin, talk with your doctor. You may need to have your blood work checked more closely while you are taking it with sofosbuvir.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using sofosbuvir while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
- If giving to your child, the dose of sofosbuvir may need to be changed as your child's weight changes. Have your child's weight checked often. Talk with the doctor before changing your child's dose.
How is this medicine (Sofosbuvir) best taken?
Use sofosbuvir as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take sofosbuvir at the same time of day.
- Take with or without food.
- Keep taking sofosbuvir as you have been told by your doctor or other health care provider, even if you feel well.
- It is important that you do not miss or skip a dose of sofosbuvir during treatment.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If you do not think about the missed dose until the next day, skip the missed dose and go back to your normal time.
- Do not take more than 1 dose of sofosbuvir in the same day.
- If you are not sure what to do if you miss a dose, call your doctor.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Feeling very tired or weak.
What are some other side effects of Sofosbuvir?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Feeling tired or weak.
- Upset stomach.
- Not able to sleep.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Sofosbuvir?
- Store in the original container at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about sofosbuvir, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Disclaimer: This information should not be used to decide whether or not to take sofosbuvir or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about sofosbuvir. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to sofosbuvir. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using sofosbuvir.
Review Date: March 7, 2018
More about sofosbuvir
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
- 46 Reviews – Add your own review/rating
- Drug class: miscellaneous antivirals
Other brands: Sovaldi