Generic Name: Baricitinib (bar i SYE ti nib)
Brand Name: Olumiant
Medically reviewed by Drugs.com. Last updated on Nov 15, 2020.
- Severe infections like tuberculosis, shingles, fungal infections and other bacterial or viral infections have happened in patients who take Olumiant (baricitinib). Sometimes, this could be deadly. The risk is greater if you also take drugs that suppress the immune system like methotrexate or corticosteroids. If you get a bad infection, your doctor may stop Olumiant (baricitinib) until the infection is under control. Call your doctor right away if you have fever, chills, or sweating; cough; muscle aches; shortness of breath; more sputum or change in color of sputum; red, warm, swollen, painful, or blistered skin; weight loss; stomach pain; diarrhea; pain with passing urine or passing urine more often; or feeling tired or weak.
- TB (tuberculosis) has been seen in patients started on Olumiant (baricitinib). These patients were exposed to TB in the past, but never got the infection. You will be tested to see if you have been exposed to TB before starting Olumiant (baricitinib).
- Lymphoma, skin cancer, and other types of cancer have happened in people treated with Olumiant (baricitinib).
- Blood clots have happened with Olumiant (baricitinib). Sometimes, these blood clots have been deadly. Call your doctor right away if you have chest, arm, back, neck, or jaw pain or pressure; coughing up blood; numbness or weakness on 1 side of your body, trouble speaking or thinking, change in balance, or change in eyesight; shortness of breath; or swelling, warmth, or pain in the leg or arm.
Uses of Olumiant:
- It is used to treat rheumatoid arthritis.
- This medicine may be used with other drugs to treat your health condition. If you are also taking other drugs, talk with your doctor about the risks and side effects that may happen.
What do I need to tell my doctor BEFORE I take Olumiant?
- If you are allergic to Olumiant (baricitinib); any part of Olumiant (baricitinib); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you have an infection or a low white blood cell count.
- If you have active TB (tuberculosis).
- If you have anemia.
- If you have any of these health problems: Kidney disease or liver disease.
- If you are taking any of these drugs: Abatacept, adalimumab, anakinra, azathioprine, certolizumab, cyclosporine, etanercept, golimumab, infliximab, probenecid, rituximab, ruxolitinib, sarilumab, tofacitinib, or tocilizumab.
- If you are breast-feeding. Do not breast-feed while you take Olumiant (baricitinib).
This is not a list of all drugs or health problems that interact with Olumiant (baricitinib).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Olumiant (baricitinib) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Olumiant?
- Tell all of your health care providers that you take Olumiant (baricitinib). This includes your doctors, nurses, pharmacists, and dentists.
- Some viral infections like herpes zoster have become active again with Olumiant (baricitinib). Tell your doctor if you have ever had a viral infection like herpes zoster. Talk with your doctor.
- Hepatitis B or C testing may be done. A hepatitis B or C infection may get worse while taking Olumiant (baricitinib).
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine may cause high cholesterol and triglyceride levels. Talk with the doctor.
- You may need to have your skin checked while you take Olumiant (baricitinib). Talk with your doctor.
- This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take Olumiant (baricitinib).
- Make sure you are up to date with all your vaccines before treatment with Olumiant (baricitinib).
- Talk with your doctor before getting any vaccines. Use of some vaccines with Olumiant (baricitinib) may either raise the chance of an infection or make the vaccine not work as well.
- You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Olumiant (baricitinib) while you are pregnant.
How is this medicine (Olumiant) best taken?
Use Olumiant (baricitinib) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with or without food.
- Keep taking Olumiant (baricitinib) as you have been told by your doctor or other health care provider, even if you feel well.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
- Change in color or size of a mole.
- A skin lump or growth.
- Feeling very tired or weak.
- Call your doctor right away if you have a swollen gland, night sweats, shortness of breath, or weight loss without trying.
- Tears in the stomach or bowel wall have happened in certain people taking Olumiant (baricitinib). Call your doctor right away if you have swelling or pain in your stomach that is very bad, gets worse, or does not go away. Call your doctor right away if you throw up blood or have throw up that looks like coffee grounds; upset stomach or throwing up that does not go away; or black, tarry, or bloody stools.
What are some other side effects of Olumiant?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Olumiant?
- Store at room temperature in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Olumiant (baricitinib) is refilled. If you have any questions about Olumiant (baricitinib), please talk with the doctor, pharmacist, or other health care provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Frequently Asked Questions
- What are the new drugs for the treatment of rheumatoid arthritis (RA)?
- Is baricitinib (Olumiant) being used to treat COVID-19?
- What type of drug is Olumiant (baricitinib)?
More about Olumiant (baricitinib)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: antirheumatics
- FDA Approval History