Generic Name: Metoclopramide Injection Solution (MET oh KLOE pra mide)
Brand Name: Reglan
Medically reviewed on July 4, 2018
- Some people who take metoclopramide injection solution may get a very bad muscle problem called tardive dyskinesia. This muscle problem may not go away even if metoclopramide injection solution is stopped. Sometimes, signs may lessen or go away over time after metoclopramide injection solution is stopped. The risk of tardive dyskinesia may be greater in people with diabetes and in older adults, especially older women. The risk is also greater the longer you take metoclopramide injection solution or with higher doses. Muscle problems may also occur after short-term use with low doses. Call your doctor right away if you have trouble controlling body movements or if you have muscle problems with your tongue, face, mouth, or jaw like tongue sticking out, puffing cheeks, mouth puckering, or chewing.
- Avoid taking metoclopramide injection solution for more than 12 weeks. Talk with the doctor.
Uses of Metoclopramide Injection Solution:
- It is used to treat heartburn.
- It is used to treat or prevent upset stomach and throwing up.
- It is used to treat gastroesophageal reflux disease (GERD; acid reflux).
- It is used to treat a slow moving GI (gastrointestinal) tract in some people.
- It may be given to you for other reasons. Talk with the doctor.
- This medicine is not approved for use in children. However, the doctor may decide the benefits of taking metoclopramide injection solution outweigh the risks. If your child has been given metoclopramide injection solution, ask the doctor for information about the benefits and risks. Talk with the doctor if you have questions about giving metoclopramide injection solution to your child.
What do I need to tell my doctor BEFORE I take Metoclopramide Injection Solution?
- If you have an allergy to metoclopramide or any other part of metoclopramide injection solution.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have ever had trouble controlling body movements or other muscle problems when taking metoclopramide injection solution.
- If you have or have ever had low mood (depression) or thoughts of killing yourself.
- If you have any of these health problems: GI (gastrointestinal) bleeding, hole in the GI tract, bowel block, pheochromocytoma, seizures, Parkinson's disease, or high blood pressure.
- If you are taking any drugs that may raise the chance of body movements you cannot control. There are many drugs that can do this. Ask your doctor or pharmacist if you are not sure.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with metoclopramide injection solution, like certain drugs that are used for depression, pain, or Parkinson's disease. There are many drugs that must not be taken with metoclopramide injection solution.
This is not a list of all drugs or health problems that interact with metoclopramide injection solution.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take metoclopramide injection solution with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Metoclopramide Injection Solution?
- Tell all of your health care providers that you take metoclopramide injection solution. This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how metoclopramide injection solution affects you.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- It may take several weeks to see the full effects.
- If you have high blood sugar (diabetes), you will need to watch your blood sugar closely.
- Avoid alcohol or other drugs and natural products that slow your actions.
- If you stop taking metoclopramide injection solution all of a sudden, you may have signs of withdrawal. Tell your doctor if you have any bad effects.
- This medicine may affect how much of some other drugs are in your body. If you are taking other drugs, talk with your doctor. You may need to have your blood work checked more closely while taking metoclopramide injection solution with your other drugs.
- If you are 65 or older, use metoclopramide injection solution with care. You could have more side effects.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using metoclopramide injection solution while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Metoclopramide Injection Solution) best taken?
Use metoclopramide injection solution as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Do not take more than what your doctor told you to take. Taking more than you are told may raise your chance of very bad side effects.
- It is given as a shot into a muscle or vein.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high or low blood pressure like very bad headache or dizziness, passing out, change in eyesight.
- Shakiness, trouble moving around, or stiffness.
- Trouble controlling body movements, twitching, change in balance, trouble swallowing or speaking.
- Shortness of breath, a big weight gain, or swelling in the arms or legs.
- Enlarged breasts.
- Nipple discharge.
- Not able to get or keep an erection.
- Period (menstrual) changes.
- A very bad and sometimes deadly health problem called neuroleptic malignant syndrome (NMS) may happen. Call your doctor right away if you have any fever, muscle cramps or stiffness, dizziness, very bad headache, confusion, change in thinking, fast heartbeat, heartbeat that does not feel normal, or are sweating a lot.
- A very bad and sometimes deadly health problem called serotonin syndrome may happen if you take metoclopramide injection solution with drugs for depression, migraines, or certain other drugs. Call your doctor right away if you have agitation; change in balance; confusion; hallucinations; fever; fast or abnormal heartbeat; flushing; muscle twitching or stiffness; seizures; shivering or shaking; sweating a lot; very bad diarrhea, upset stomach, or throwing up; or very bad headache.
- Patients who take metoclopramide injection solution may be at a greater risk of having thoughts or actions of suicide. The risk may be greater in people who have had these thoughts or actions in the past. Call the doctor right away if signs like low mood (depression), nervousness, restlessness, grouchiness, panic attacks, or changes in mood or actions are new or worse. Call the doctor right away if any thoughts or actions of suicide occur.
What are some other side effects of Metoclopramide Injection Solution?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Loose stools (diarrhea).
- Feeling sleepy.
- Upset stomach.
- Feeling tired or weak.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Metoclopramide Injection Solution?
- If you need to store metoclopramide injection solution at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time metoclopramide injection solution is refilled. If you have any questions about metoclopramide injection solution, please talk with the doctor, pharmacist, or other health care provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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