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Erythromycin and Benzoyl Peroxide Gel

Generic Name: Erythromycin and Benzoyl Peroxide Gel (er ith roe MYE sin & BEN zoe il per OKS ide)
Brand Name: Benzamycin

Medically reviewed on September 5, 2018

Uses of Erythromycin and Benzoyl Peroxide Gel:

What do I need to tell my doctor BEFORE I take Erythromycin and Benzoyl Peroxide Gel?

  • If you have an allergy to erythromycin, benzoyl peroxide, or any other part of erythromycin and benzoyl peroxide gel.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

This medicine may interact with other drugs or health problems.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take erythromycin and benzoyl peroxide gel with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Erythromycin and Benzoyl Peroxide Gel?

  • Tell all of your health care providers that you take erythromycin and benzoyl peroxide gel. This includes your doctors, nurses, pharmacists, and dentists.
  • Certain acne products that contain benzoyl peroxide or salicylic acid can rarely cause very bad and sometimes life-threatening allergic reactions or very bad irritation. Before first use, you may need to follow certain steps to make sure you do not have an allergic reaction. Use erythromycin and benzoyl peroxide gel as you were told by the doctor or read the package label. Talk with the doctor.
  • Do not use longer than you have been told by the doctor.
  • Use of other skin products while using erythromycin and benzoyl peroxide gel may cause more irritation.
  • Talk with your doctor before you use other drugs or products on your skin.
  • Use care when putting on. It may bleach hair or colored fabric.
  • You may get sunburned more easily. Avoid sun, sunlamps, and tanning beds. Use sunscreen and wear clothing and eyewear that protects you from the sun.
  • Diarrhea, bloody diarrhea, and a certain bowel problem (colitis) have happened with erythromycin and benzoyl peroxide gel. Very bad colitis may lead to death. Call your doctor right away if you have stomach pain or cramps, very bad or watery diarrhea, or bloody diarrhea. Do not try to treat diarrhea without first checking with your doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using erythromycin and benzoyl peroxide gel while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Erythromycin and Benzoyl Peroxide Gel) best taken?

Use erythromycin and benzoyl peroxide gel as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Do not take erythromycin and benzoyl peroxide gel by mouth. Use on your skin only. Keep out of your mouth, nose, and eyes (may burn).
  • Wash your hands before and after use.
  • Wash and rinse affected skin with warm water, then pat dry.
  • Put a thin layer on the affected skin and rub in gently.
  • Do not put on irritated skin.
  • Put on gel at the same time of day.

What do I do if I miss a dose?

  • Put on a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not put on 2 doses at the same time or extra doses.

See also: Dosage Information (in more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Very bad skin irritation.

What are some other side effects of Erythromycin and Benzoyl Peroxide Gel?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Erythromycin and Benzoyl Peroxide Gel?

  • Store in a refrigerator. Do not freeze.
  • Throw away any part not used after 3 months.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about erythromycin and benzoyl peroxide gel, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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