Elbasvir and Grazoprevir
Generic Name: Elbasvir and Grazoprevir (ELB as vir & graz OH pre vir)
Brand Name: Zepatier
Medically reviewed on July 4, 2018
- You will be tested for hepatitis B before starting elbasvir and grazoprevir. In people who have had hepatitis B before or carry the virus, the virus has become active again during or after treatment with drugs like this one. This can lead to very bad and sometimes deadly liver problems. People who have hepatitis B and hepatitis C need to be watched closely during and after treatment with elbasvir and grazoprevir. If you have questions, talk with your doctor.
Uses of Elbasvir and Grazoprevir:
- It is used to treat long-term hepatitis C infections.
- This medicine may be used with other drugs to treat hepatitis C. If you are also taking other drugs to treat hepatitis C, talk with the doctor about the risks and side effects that may happen.
What do I need to tell my doctor BEFORE I take Elbasvir and Grazoprevir?
- If you have an allergy to elbasvir and grazoprevir or any part of elbasvir and grazoprevir.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you have liver problems other than hepatitis C.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with elbasvir and grazoprevir, like certain drugs that are used for HIV, infections, or seizures. There are many drugs that must not be taken with elbasvir and grazoprevir.
- If you are taking St. John's wort. Do not take St. John's wort with elbasvir and grazoprevir. This medicine may not work as well.
This is not a list of all drugs or health problems that interact with elbasvir and grazoprevir.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take elbasvir and grazoprevir with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Elbasvir and Grazoprevir?
- Tell all of your health care providers that you take elbasvir and grazoprevir. This includes your doctors, nurses, pharmacists, and dentists.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine interacts with many other drugs. The chance of side effects may be raised or how well elbasvir and grazoprevir works may be lowered. Check with your doctor and pharmacist to make sure that it is safe for you to take elbasvir and grazoprevir with all of your other drugs (prescription or OTC, natural products, vitamins).
- This medicine may affect how much of some other drugs are in your body. If you are taking other drugs, talk with your doctor. You may need to have your blood work checked more closely while taking elbasvir and grazoprevir with your other drugs.
- Do not stop taking elbasvir and grazoprevir without calling the doctor who ordered it for you.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using elbasvir and grazoprevir while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Elbasvir and Grazoprevir) best taken?
Use elbasvir and grazoprevir as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with or without food.
- Do not take elbasvir and grazoprevir out of the blister pack until you are ready to take it. Take elbasvir and grazoprevir right away after opening the blister pack. Do not store the removed drug for future use.
- Keep taking elbasvir and grazoprevir as you have been told by your doctor or other health care provider, even if you feel well.
- It is important that you do not miss or skip a dose of elbasvir and grazoprevir during treatment.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
- If you are not sure what to do if you miss a dose, call your doctor.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- Feeling very tired or weak.
What are some other side effects of Elbasvir and Grazoprevir?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Elbasvir and Grazoprevir?
- Store in the original container at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about elbasvir and grazoprevir, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about elbasvir/grazoprevir
- Elbasvir/grazoprevir Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- En Español
- 40 Reviews
- Drug class: antiviral combinations
Other brands: Zepatier