Skip to Content
New To Chronic Myeloid Leukemia? Get Information Today >>

Canakinumab

Generic Name: Canakinumab (can a KIN ue mab)
Brand Name: Ilaris, Ilaris (150mg Delivered)

Uses of Canakinumab:

  • It is used to treat certain periodic fever syndromes.
  • It is used to treat juvenile arthritis.
  • It may be given to you for other reasons. Talk with the doctor.

What do I need to tell my doctor BEFORE I take Canakinumab?

  • If you have an allergy to canakinumab or any other part of canakinumab.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Hepatitis B, hepatitis C, HIV, or any other infection.
  • If you are taking any of these drugs: Adalimumab, anakinra, certolizumab, etanercept, golimumab, infliximab, rilonacept, tocilizumab, or tofacitinib.

This is not a list of all drugs or health problems that interact with this medicine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take canakinumab with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Canakinumab?

  • Tell all of your health care providers that you take this medicine. This includes your doctors, nurses, pharmacists, and dentists.
  • This medicine may add to the chance of getting some types of cancer. Talk with the doctor.
  • You may have more chance of getting an infection. Wash hands often. Stay away from people with infections, colds, or flu.
  • Very bad infections have been reported with use of canakinumab. If you have any infection, are taking antibiotics now or in the recent past, or have many infections, talk with your doctor.
  • You will need a TB (tuberculosis) test before starting this medicine.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • Make sure you are up to date with all your vaccines before treatment with canakinumab.
  • Talk with your doctor before getting any vaccines. Use with this medicine may either raise the chance of an infection or make the vaccine not work as well.
  • This medicine may affect how much of some other drugs are in your body. If you are taking other drugs, talk with your doctor. You may need to have your blood work checked more closely while taking canakinumab with your other drugs.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using this medicine while you are pregnant.
  • Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.

How is this medicine (Canakinumab) best taken?

Use canakinumab as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • It is given as a shot into the fatty part of the skin.

What do I do if I miss a dose?

  • Call your doctor to find out what to do.

See also: Dosage Information (in more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
  • Cough that does not go away.
  • Weight loss.
  • Dizziness or passing out.
  • Very bad irritation where the shot was given.
  • Trouble swallowing.
  • Very upset stomach or throwing up.
  • A heartbeat that does not feel normal.
  • A very bad and sometimes deadly problem called Macrophage Activation Syndrome (MAS) may rarely happen in people with juvenile arthritis. Tell your doctor right away if your arthritis signs get worse or if you have a fever for more than 3 days, a cough that does not go away, redness in one part of your body, or a warm feeling or swelling of your skin.

What are some other side effects of Canakinumab?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Irritation where the shot is given.
  • Headache.
  • Belly pain.
  • Upset stomach or throwing up.
  • Loose stools (diarrhea).
  • Muscle pain.
  • Weight gain.
  • Sore throat.
  • Runny nose.
  • Flu-like signs.
  • Signs of a common cold.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Canakinumab?

  • If you need to store this medicine at home, talk with your doctor, nurse, or pharmacist about how to store it.

Consumer Information Use and Disclaimer

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Check with your pharmacist about how to throw out unused drugs.
  • This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time canakinumab is refilled. If you have any questions about this medicine, please talk with the doctor, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This information should not be used to decide whether or not to take canakinumab or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to canakinumab. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using this medicine.

Review Date: October 4, 2017

Hide