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Adult-Onset Still Disease

Medically reviewed by Drugs.com. Last updated on Nov 3, 2024.

What is adult-onset Still disease (AOSD)?

AOSD is a rare autoinflammatory disease. This means your immune system makes too much inflammation and attacks its own healthy tissues, such as your joints and muscles. Organs such as your heart, liver, or kidneys may also be affected.

What increases my risk for AOSD?

The cause of AOSD is not known. AOSD usually starts between 16 and 25 years or 35 and 45 years of age. A family history of rheumatoid arthritis may also increase your risk.

What are the signs and symptoms of AOSD?

How is AOSD diagnosed?

No test is available to diagnose AOSD. Other diseases and conditions need to be ruled out, such as an infection. Your healthcare provider will examine you and ask about your symptoms. Tell your provider if you have a family history of arthritis. Your provider may refer you to a rheumatologist (inflammatory disease specialist). You may also need any of the following:

How is AOSD treated?

AOSD cannot be cured or prevented. Treatment focuses on slowing the progression of AOSD and preventing or managing flares. A flare means you are having symptoms, such as joint stiffness or a rash. AOSD flares are usually triggered by stress. You may also develop chronic rheumatoid arthritis that will need to be managed. The following may be used to help control symptoms of AOSD:

Treatment options

The following list of medications are related to or used in the treatment of this condition.

What can I do to manage AOSD?

Wellness Tips

When should I seek immediate care?

When should I call my doctor or rheumatologist?

Care Agreement

You have the right to help plan your care. Learn about your health condition and how it may be treated. Discuss treatment options with your healthcare providers to decide what care you want to receive. You always have the right to refuse treatment. The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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