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Medications for Juvenile Idiopathic Arthritis

About Juvenile Idiopathic Arthritis

Juvenile Idiopathic Arthritis, also called juvenile rheumatoid arthritis, is thought to be an autoimmune disease. The lining of the joint (called synovial membrane) becomes inflamed and enlarged, limiting movement and causing pain and tenderness. The onset occurs before age 16.

Drugs used to treat Juvenile Idiopathic Arthritis

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
methotrexate 4.5 2 reviews
Rx X N X

Generic name: methotrexate systemic

Brand names:  Rasuvo, Otrexup, Xatmep, RediTrex …show all

Drug class: antimetabolites, antirheumatics, antipsoriatics, other immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Humira 6.7 3 reviews
Rx B N

Generic name: adalimumab systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Enbrel 8.5 6 reviews
Rx B N

Generic name: etanercept systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Orencia 7.0 2 reviews
Rx C N

Generic name: abatacept systemic

Drug class: antirheumatics, selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Actemra 7.8 4 reviews
Rx C N

Generic name: tocilizumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

etanercept 8.5 6 reviews
Rx B N

Generic name: etanercept systemic

Brand names:  Enbrel, Erelzi, Eticovo

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

adalimumab 6.7 3 reviews
Rx B N

Generic name: adalimumab systemic

Brand names:  Humira, Amjevita, Cyltezo, Abrilada, Hadlima, Hyrimoz, Hulio …show all

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

abatacept 7.0 2 reviews
Rx C N

Generic name: abatacept systemic

Brand name:  Orencia

Drug class: antirheumatics, selective immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

tofacitinib Rate Add review
Rx C N

Generic name: tofacitinib systemic

Brand name:  Xeljanz

Drug class: antirheumatics

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Xeljanz Rate Add review
Rx C N

Generic name: tofacitinib systemic

Drug class: antirheumatics

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Ilaris Rate Add review
Rx C N

Generic name: canakinumab systemic

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Rasuvo Rate Add review
Rx X N X

Generic name: methotrexate systemic

Drug class: antimetabolites, antirheumatics, antipsoriatics, other immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

tocilizumab 6.4 5 reviews
Rx C N

Generic name: tocilizumab systemic

Brand name:  Actemra

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Otrexup Rate Add review
Rx X N X

Generic name: methotrexate systemic

Drug class: antimetabolites, antirheumatics, antipsoriatics, other immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Xatmep Rate Add review
Rx X N X

Generic name: methotrexate systemic

Drug class: antimetabolites, antirheumatics, other immunosuppressants

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

RediTrex Rate Add review
Rx X N X

Generic name: methotrexate systemic

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Amjevita Rate Add review
Rx B N

Generic name: adalimumab systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

canakinumab Rate Add review
Rx C N

Generic name: canakinumab systemic

Brand name:  Ilaris

Drug class: interleukin inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

infliximab Off-label 9.0 1 review
Rx B N

Generic name: infliximab systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: A-Z Drug Facts, AHFS DI Monograph

Off-label: Yes

Erelzi Rate Add review
Rx B N

Generic name: etanercept systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

Cyltezo Rate Add review
Rx B N

Generic name: adalimumab systemic

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

Abrilada Rate Add review
Rx B N

Generic name: adalimumab systemic

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

Eticovo Rate Add review
Rx B N

Generic name: etanercept systemic

Drug class: antirheumatics, TNF alfa inhibitors

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Hadlima Rate Add review
Rx B N

Generic name: adalimumab systemic

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

Hyrimoz Rate Add review
Rx B N

Generic name: adalimumab systemic

Drug class: TNF alfa inhibitors

For consumers: dosage, interactions, side effects

Learn more about Juvenile Idiopathic Arthritis

Mayo Clinic Reference

Legend

Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription Only.
OTC Over the Counter.
Rx/OTC Prescription or Over the Counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.