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Generic Vivactil Availability

Last updated on Sep 10, 2026.

Vivactil is a brand name of protriptyline, approved by the FDA in the following formulation:

VIVACTIL (protriptyline hydrochloride - tablet; oral)
Manufacturer Approval date Strengths [AB]
TEVA WOMENS Approved Prior to Jan 1, 1982
  • 5MG (discontinued) [AB]
  • 10MG (discontinued) [AB]

All of the above formulations have been discontinued.

Has a generic version of Vivactil been approved?

Yes, the FDA has approved a generic version of Vivactil. However, FDA approval doesn't guarantee the generic will be available in pharmacies.

VIVACTIL (protriptyline hydrochloride tablet; oral)
Manufacturer Approval date Strengths [AB]
SIGMAPHARM LABS LLC May 3, 2010
  • 5MG [AB]
  • 10MG [AB]
EPIC PHARMA LLC November 19, 2012
  • 5MG [AB]
  • 10MG [AB]
Discontinued generic versions

Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Vivactil. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.

See also: Generic Drug FAQ.

Generic Vivactil prices

The pricing data below reflects current availability in the marketplace and indicates that the medication is available for purchase.

DrugFormStrengthDrugs.com Price Guide
Protriptyline Hydrochlorideoral tablet5 mgfrom $48.86 for 30
Protriptyline Hydrochlorideoral tablet10 mgfrom $49.99 for 30

See all prices for: Protriptyline Hydrochloride

Generic Vivactil images

Images of protriptyline (generic Vivactil). See all images

Pill E 7 Yellow Round is Protriptyline Hydrochloride
1 / 4
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E 7

Protriptyline Hydrochloride
Sigmapharm Laboratories, LLC
Strength
10 mg
Imprint
E 7
Color
Yellow
Shape
Round
View details
Pill E 4 Orange Round is Protriptyline Hydrochloride
1 / 3
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E 4

Protriptyline Hydrochloride
Sigmapharm Laboratories, LLC
Strength
5 mg
Imprint
E 4
Color
Orange
Shape
Round
View details
Pill E96 Orange Round is Protriptyline Hydrochloride
1 / 2
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E96

Protriptyline Hydrochloride
Epic Pharma, LLC
Strength
5 mg
Imprint
E96
Color
Orange
Shape
Round
View details

Generic Vivactil Marketing Start Dates

Marketing start dates are when each generic version first became available from each manufacturer.

Start Date Labeler NDC Number Form Price
January 9, 2013 Epic Pharma, LLC 42806-096 Tablet, film coated 5, mg/1
January 9, 2013 Epic Pharma, LLC 42806-097 Tablet, film coated 10, mg/1
March 2, 2020 Sigmapharm Laboratories, LLC 42794-004 Tablet, film coated 5, mg/1
March 2, 2020 Sigmapharm Laboratories, LLC 42794-007 Tablet, film coated 10, mg/1

Discontinued generic versions of Vivactil

The following generic formulations of Vivactil have been discontinued:

Manufacturer Approval date Strengths [AB]
CHARTWELL RX August 24, 1995
  • 5MG (discontinued) [AB]
  • 10MG (discontinued) [AB]

Related/similar drugs

Glossary

Term Definition
Drug Patent A drug patent is assigned by the U.S. Patent and Trademark Office and assigns exclusive legal right to the patent holder to protect the proprietary chemical formulation. The patent assigns exclusive legal right to the inventor or patent holder, and may include entities such as the drug brand name, trademark, product dosage form, ingredient formulation, or manufacturing process A patent usually expires 20 years from the date of filing, but can be variable based on many factors, including development of new formulations of the original chemical, and patent infringement litigation.
Drug Exclusivity Exclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Exclusivity periods can run from 180 days to seven years depending upon the circumstance of the exclusivity grant.
AB Products meeting necessary bioequivalence requirements. Multisource drug products listed under the same heading (e.g. identical active ingredients, dosage form, and routes of administration) and having the same strength (see Therapeutic Equivalence-Related Terms, Pharmaceutical Equivalents) generally will be coded AB if a study is submitted demonstrating bioequivalence. In certain instances, a number is added to the end of the AB code to make a three character code (e.g. AB1, AB2, AB7). Three-character codes are assigned only in situations when more than one reference listed drug of the same strength has been designated under the same heading. Two or more reference listed drugs are generally selected only when there are at least two potential reference drug products which are not bioequivalent to each other. If a study is submitted that demonstrates bioequivalence to a specific listed drug product, the generic product will be given the same three-character code as the reference listed drug it was compared against.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.