Which is better for panic attacks? Amitriptyline of Zoloft?

Hi, LouAnn!
That's a tough question because the better medication is the one that works best for you. Everyone responds differently to these medications so what works well for one person may not for another person.
Personally, I had much better luck with Zoloft and took it for several years.
These reviews might be helpful:
https://www.drugs.com/comments/amitriptyline/for-anxiety-stress.html
https://www.drugs.com/comments/sertraline/zoloft-for-panic-disorder.html