Due to chemo, I haveno nerves in my legs, also have restless leg syndrome, I am taking 150mg 3x aday,and it works but not quite,always have some leg pain,,, anf the legs ,I do not have complete control over at all times can the doc,increase it , she seems to think I am taking the upper limits of the meds.But my other doc. says I am safe with an increase.
Lyrica,what is the highest dose a person can take?
Question posted by Traveler_213lo on 8 June 2011
Last updated on 1 July 2018
5 Answers
Craigdallen
13 June 2017
I've been on Lyrica for 2 months. I have a Brachial Plexus nerve injury with RSD. Basically my right arm hurts major big time with nerve pain. Without Lyrica the pain is a level 8 all the time non-stop 24/7.
I started Lyrica at 150mg 2x day (300mg total). This worked partially. For 6 hours I was great, no pain. Then for 6 hours I was in dire can't function pain.
I switched to 150mg 3x day (450mg total). A lot better, but 6 hours of goodness and 2 hours of FU pain.
The doctor switched me to Horizant (which is extended release gabapentin). This drug did nothing for me. No relief or pain management at all. Went back to Lyrica and things are way better.
I tried (by myself) 100mg 4x day. This work great for duration but not enough for pain. I was in level 3-4 pain all the time.
I'm now trying 150mg 4x day (600mg total). It seems to be just right.
Now I have to convince my doctor to prescribe based on this. 4x day is not a recommended dosing. But the damn drug doesn't last any longer than 6 hours.
The only side affects for me are slight short term memory issues. And trying to get out the next word when talking.
But I can't live in constant dire OMG pain.
tlt63tdt
2 July 2018
I also have a right brachial plexus nerve injury with RSD I'm in pain non stop 24/7. I take multiple opioids a day but I also take lyric 600mg twice a day this is the dose that my doctor started me off with from the beginning. I have a very high tolerance for med and my body adjust to meds quickly. The lyric does work I quit taking it just to see if it would make a difference and it does without the lyric my pain level is a 10 but on the lyric my pain level is between a 4-5 and this is all day everyday.
ReenaGibson
12 May 2017
My doctor gave me control over the dose I was on to increase in increments every 10 days if needed to a maximum of 600mg a day,
If you''re 150mg x 3 a day then at 450mg a day you are on the upper limits with an extra 150mg to go before before you reach the max allowed dose. So yes, there is room for an increase but not much.
Dr Ngcobo
12 May 2017
The maximum dose is actually 600mg per day. Since her symptoms are not adequately controlled, her dose can be increased to 300mg twice daily, which makes 600mg per day.
LaurieShay
8 June 2011
Hey Traveler,
While the recommended maximum dose of Lyrica is 100mg three times a day, patients who do not experience sufficient pain relief following 2 to 4 weeks of treatment with 300 mg/day, and who are able to tolerate LYRICA, may be treated with up to 300 mg two times a day, or 200 mg three times a day (600 mg/day). In view of the dose-dependent adverse reactions and the higher rate of treatment discontinuation due to adverse reactions, reserve dosing above 300 mg/day for those patients who have on-going pain and are tolerating 300 mg daily [see Adverse Reactions (6.1)].
So yes, the dose could be increased another 150 mgs a day if you are tolerating the Lyrica well.
Hope this helps,
Laurie
Tygrlilie35
8 June 2011
Hello, I also have restless leg syndrome and take 4mgs of Requip (Ropinerole) every night before I go to bed. I don't have cancer, I have Crohn's disease which can be very painful, I used to have an internal pain pump that had a catheter that was attached to the pump and placed into the epidural space near my spine. It must have been leaning against a nerve ending or something because I developed restless leg syndrome soon after I had my pump put in. I've since had the pump removed because I got a severe infection from it, I still have restless leg syndrome though. Having my abdomen cut so many times and having nerve endings growing back has not helped the condition. Like I said I take Requip for it and it works really well. You should ask your doctor if you can try it along with the Lyrica. Cymbalta also works for nerve pain, I was recently started on 20mgs of Cymbalta daily for nerve pain in my abdomen and mild depression. I hope I've been of some help, feel better, Tygrlilie
George34
20 March 2014
Tygrlilie35 what was the cause of your abdominal pain? I have lower abdominal pain they think is from my lower back surgerys?
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- Lyrica uses and safety info
- Lyrica prescribing info & package insert (for Health Professionals)
- Side effects of Lyrica (detailed)
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