The elimination half-life of a medication is the time it takes for blood levels of the medication to be reduced by half. For trazodone the half-life is approximately 5 to 13 hours. This means that every 5 to 13 hours, the level in your blood will drop by 50 percent.
It takes on average 5.5 elimination half lives for a drug to be eliminated from your system. Metabolism, age, health, weight and the amount and frequency of the drug taken, are all factors that can affect the rate at which the body can clear the drug from your system.
After a single dose in a healthy adult with an elimination half-life of 10 to 12 hours, Trazodone will be mostly out of your system in one to three days.
- Trazodone Information for Consumers
- Trazodone Information for Healthcare Professionals (includes dosage details)
- Side Effects of Trazodone (detailed)
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