I had been on Wellbutrin but had to stop due to increased agitation and rage issues. I am now on Celexa and have noticed weight gain. I also wake up with puffiness around the eyes. Has anyone experienced this? Will it go away?? The Celexa is supposed to treat depression, but if I keep gaining weight, I really WILL be depressed!!
Has anyone noticed weight gain with Celexa?
Question posted by Valatron on 30 Sep 2009
Last updated on 27 June 2023 by WildcatVet
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
89 Answers
As with most, if not all, antidepressants Celexa has the potential to cause weight changes in 10% or less of users. With Celexa these weight changes can go either way... loss or gain.
"Metabolic
Common (1% to 10% of users): Anorexia, decreased/increased weight, decreased/increased appetite"
If you do gain weight exercise and diet should be helpful. Watch for increased appetite and avoid sugar and carbohydrates. Ask your doctor about possibly decreasing your dosage.
What it may come down to is a decision to take the slight risk or continue to live with your depression and/or anxiety issues.
YES! I went on this drug in my 30's. A 20 tablet, and it helped my depression a lot, but made me not care at all and I gained like 60lbs over the course of 3 years. Then when all was said and done, I was even more depressed when I started to realize how heavy I had become. I went off of it, but it's been a struggle ever since to remove this weight. I did use it after that but just off and on, and only took 10 and didn't seem to affect my weight on just 10 and it would take the edge off my anxiety. But I don't think I would ever go on that drug ever again. Only because getting off was another thing. I remember having like crazy like brain tingling almost felt electrical when I was trying to wean off of it. Good luck hope this info helps but everyone is different.
Update! Since stopping medication I'm very slowly losing the weight, I lost 9kg so far, but I look and feel sooo much better already. It was impossible to lose the weight on citalopram it just kept going up, but now I'm glad its slowly going down :) took quite a few months for my body to get back to normal, but I'm finally here :)
Hello! I wanted to chime in on my experience. I took Celexa for 4 months due to anxiety. (10 mg) per day. The medication did wonders for eliminating elevated stress levels but I didn't like the weight gain of roughly 8 pounds so I stopped. I've been working out with cardio (Peleton) , weight training, cutting calories, low carb, diet products etc and it's been extremely challenging to lose weight. I'm a 6' 49 year old male, stuck at 230 pounds where I was typically 220. I'm encouraged to hear that others have experienced that their metabolism returned to normal at roughly 6 months. I'm in great cardiovascular shape and I've put on muscle so there are some silver linings for sure. Good luck!
I feel like I can't win. I have moderately severe anxiety; enough to make my day-to-day kind of miserable and make me irritable as well as irritate the people around me. My anxiety takes a lot of enjoyment out of my life.
Celexa works sooooooo well for me. I am like a different person on it. However, even on a tiny dose (10 mg) I've already put on 10 pounds over 6 months or so. (Unfortunately I didn't have much leeway for weight gain so this has put me into the overweight category.)
It just occurred to me that it is the Celexa! My stomach is like a black hole when I am on it. I am hungry ALL of the time. I am insatiable. It's like having PMS every day And now I recall that this happened to me years ago--when I was on a much higher dose and gained a ton more weight!!
Obviously I can't stay on it. It is so frustrating to have your only choice to be super chill and relaxed and pleasant--but be less healthy and look it--or to stressed out and edgy but a normal weight. Now I'm stressed out and edgy and also carrying an extra 10 pounds that I can't really afford.
I gained 15 pounds in the 5 months I was on it. I was only on 10 mg. This was an upsetting side effect for me and I stopped taking the medication. Now, I’m trying super hard to lose this weight. My weight has remained the same for years and for some reason went way up when I took this medication.
Oddly, I lost weight on Celexa. I just wasn’t hungry at all.
I've been on Citalopram 40mg for about 2 years now and gained about 30kg, despite improving my diet, eating only 1500cals a day and exercising 3 times per week or more.
Since therapy is going well, and I'm feeling much better, I will stop my medication this week. (Well start the process of quitting).
It was really comforting reading about all the other experiences, and feel less insane about the whole weight gain thing.
I don't know if I've answer this question before, but, I never gained weight with Celexa. I am now on Venlafaxine (Effexor) and no gain with this either. I have always been thin... and still am. However, as opposed to eating if I am not feeling well, I lose my appetite. I am lucky to be holding my weight.
A useful piece of information: I get Migraine headaches. My (new) doctor switched me to this Rx as it is thought to help prevent migraines. My neurologist agrees.
I’m so relieved to read all the answers above. I’ve been on Celexa for almost 2 years and I’ve gained 15 pounds that won’t budge. I’ve been on every diet, low calories, and highly active. I even tried Saxenda to lose weight and NOTHING has worked. I stopped taking it 10 days ago and while my anxiety has returned, I can see a difference in my appetite already.
I realize that some people say the benefits out “weigh” the weigh gain but the weight gain has me working with no progress and that’s just torture.
Just scrolling through comments realizing I'm not alone in the weight gain issue. I had began taking this when diagnosed with breast cancer 2018, and now thinking of changing it. I do believe my appetite increased a whole lot. I noticed after chemo that I was hungry. I also began gaining about 5 lbs per month after chemo. So within 1 year I have gained 50 lbs. In less than 1 year yikes! I have never been on an antidepressant so I didn't think anything of the weight gain, really didn't notice until my follow-ups showed it. My heart was beating rapidly, nervous, anxious, confusion, and on tramadol at the time to manage pain. Well turns out I wasn't suppose to take the two together. So make sure your doctors are aware, don't assume they check interactions between medicines are safe, while most do some don't. Which led me to think maybe the medicines were associated with weight gain issue as well.
I feel as though I'm hungry all the time. I'm very active, but never satisfied where hunger is concerned. Clearly a lot of us gain on this, for me it's the hunger, not filling satisfied i can relate. Has anyone stopped taking 20mg cold turkey? Thanks.
I’ve taken Celexa for about 4 months now 20mg and have unfortunately noticed a significant amount of weight, I’ve gained. I’d say about 10lbs. I’m very active! So this has been a really big surprise to me lol. I go to the gym 6 times a week and love a very healthy lifestyle. Three days of boxing (cardio) and three of weights and somehow I can’t seem to lose the weight. Pretty annoying lol.
I definitely feel it’s the medication. I have gotten better at managing my cravings, since it’s made me hungrier but also noticed I’m always so thirsty!! So I’m not sure what’s going on... I hope this helps!
I actually lost a pant size on Celexa. I just wasn’t hungry during the day. Celexa curbed my appetite. Unfortunately I had to stop taking it due to extreme dry mouth.
I have been on antidepressants for about twenty six years. I had become very thin from depression and lose of appetite. After starting meds I regained my normal weight and continued to gain and gained... I am now 100lbs overweigh and can’t loose it! Withdrawal symtoms are sooo bad I can’t get off the meds!!! And they don’t even work well anymore. What is my problem? Only that I am depressed because I am fat.
Hi, 223! Symptoms of discontinuation syndrome can be greatly reduced or eliminated with a tapering dose schedule over several weeks to months as prescribed by your doctor. Also, antidepressants have a tendency to "poop out" after long term use. Consult with your doctor about some of the newer more weight neutral antidepressants or an add-on like Abilify or Rexulti.
I have been on Celexa for well over a decade - best guess between 15 and 20 years. I am close to 5'11". I weigh just under 160 lbs. I am not an exercise nut, but I am admittedly somewhat picky about what I eat. Just somewhat. I am not a vegetarian, nor a vegan. I just eat in moderation.
My point is, no, Celexa has caused no weight gain for me. Honestly, I don't understand how a medicine can cause weight gain, but, I'm not a pharmacologist.
Phildo, I have been on Celexa for three months and haven't experienced any weight gain. I'm actually focusing on my physical health now that I have a good grip on my mental situation and have lost some weight. I did go through a period after starting Celexa where I felt hungry all of the time but I was able to work through it.
Jim - that's good news. I think, in general, I am a "Eat to live" rather than a "Live to eat" person. Also, as I am 95% retired now, I am much less physically active... therefore less appetite. I've been slim my entire life. So, I guess it all adds ups to one thing - Celexa hasn't changed my weight situation at all.
Unfortunately, the biggest change on my body in general is my physical age. I hope I can get into an exercise routine and work on my physical self as you are. I am NOT known for my propensity for exercise! Continued good luck to you!
Related topics
celexa, wellbutrin, depression, weight loss (obesity/overweight), agitation, weight
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