Klonopin Wafer Side Effects
Generic name: clonazepam
Note: This document contains side effect information about clonazepam. Some of the dosage forms listed on this page may not apply to the brand name Klonopin Wafer.
Some side effects of Klonopin Wafer may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to clonazepam: oral tablet, oral tablet disintegrating
Get emergency medical help if you have any of these signs of an allergic reaction while taking clonazepam (the active ingredient contained in Klonopin Wafer) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, depression, anxiety, or if you feel agitated, irritable, hostile, aggressive, restless, hyperactive (mentally or physically), or have thoughts about suicide or hurting yourself.
Call your doctor at once if you have a serious side effect such as:
confusion, hallucinations, unusual thoughts or behavior;
weak or shallow breathing;
unusual risk-taking behavior, no fear of danger;
unusual or involuntary eye movements;
pounding heartbeats or fluttering in your chest;
painful or difficult urination, urinating less than usual;
pale skin, easy bruising or bleeding; or
new or worsening seizures.
Less serious side effects of clonazepam may include:
drowsiness, dizziness, problems with thinking or memory;
tired feeling, muscle weakness, loss of balance or coordination;
slurred speech, drooling or dry mouth, sore gums;
runny or stuffy nose;
loss of appetite, nausea, diarrhea, constipation;
sleep problems (insomnia);
skin rash; or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For Healthcare Professionals
Applies to clonazepam: oral tablet, oral tablet disintegrating
Nervous system side effects are common, particularly at the initiation of therapy and include drowsiness, fatigue, ataxia, confusion, depression, daytime anxiety, and amnesia. Nystagmus, diplopia, vertigo, headache, respiratory depression, tremor and slurred speech have also been reported less frequently.
Sedation may initially occur in up to 50% of treated patients. Ataxia may occur in 30% of patients. Five to 6% of patients treated with clonazepam for seizures may develop more frequent seizures or a new type of seizure disorder. Weakness and hypotonia have also been reported. A case report has suggested that clonazepam may induce Tourette's syndrome.
Behavioral problems have been reported in as many as 30% of treated patients.
Psychiatric side effects have been reported and include behavioral disinhibition (particularly sexual disinhibition), depression, and rarely, psychosis and mania.
Other side effects have included withdrawal symptoms (similar to those which may occur after withdrawal of barbiturates and alcohol) which have been reported after abrupt cessation of clonazepam (the active ingredient contained in Klonopin Wafer) Specifically, seizures, agitation, restlessness, anxiety, delirium, psychosis, dysphoria, insomnia, tremor, abdominal cramps, vomiting, rash, and sweating have been reported to have occurred, especially after long-term therapy.
In one study, anorgasmia occurred in 44% of patients treated with clonazepam (the active ingredient contained in Klonopin Wafer) while anorgasmia occurred in only 6% of patients treated with placebo.
Genitourinary side effects may include urinary incontinence, anorgasmia, ejaculatory delay, and erectile dysfunction.
Hematologic side effects including thrombocytopenia have been reported rarely.
Gastrointestinal side effects including hypersalivation, diarrhea, constipation, nausea, increased appetite, and anorexia have been reported.
Respiratory side effects including bronchial hypersecretion have been reported.
Dermatologic side effects have included cases of rashes associated with clonazepam (the active ingredient contained in Klonopin Wafer) therapy. A case of erythema multiforme associated with clonazepam therapy has also been reported.
Clonazepam (the active ingredient contained in Klonopin Wafer) is contraindicated in patients with narrow angle glaucoma.
Ocular side effects including acute worsening of narrow angle glaucoma is possible with clonazepam therapy.
Metabolic side effects have included exacerbation of seizure disorders in some patients with acute intermittent porphyria. However, a case report has suggested that clonazepam (the active ingredient contained in Klonopin Wafer) may be beneficial in this setting as well.
More Klonopin Wafer resources
- Klonopin Wafer orally disintegrating tablets MedFacts Consumer Leaflet (Wolters Kluwer)
- Clonazepam Professional Patient Advice (Wolters Kluwer)
- Clonazepam Prescribing Information (FDA)
- Clonazepam Monograph (AHFS DI)
- Klonopin Consumer Overview
- Klonopin Prescribing Information (FDA)
- clonazepam Advanced Consumer (Micromedex) - Includes Dosage Information
- clonazepam MedFacts Consumer Leaflet (Wolters Kluwer)
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