Bactramycin Side Effects
Generic name: lincomycin
Note: This document contains side effect information about lincomycin. Some of the dosage forms listed on this page may not apply to the brand name Bactramycin.
Some side effects of Bactramycin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to lincomycin: capsule, solution
Along with its needed effects, lincomycin (the active ingredient contained in Bactramycin) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking lincomycin:More common
- Abdominal or stomach cramps and pain (severe)
- abdominal tenderness
- diarrhea (watery and severe), which may also be bloody
- Skin rash, redness, and itching
- sore throat and fever
- unusual bleeding and bruising
Note: Some of the above side effects may also occur up to several weeks after you Stop taking lincomycin.
Some side effects of lincomycin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Diarrhea (mild)
- nausea and vomiting
- stomach pain
- Itching of rectal or genital (sex organ) areas
For Healthcare Professionals
Applies to lincomycin: compounding powder, injectable solution, oral capsule
Gastrointestinal side effects have included glossitis, stomatitis, nausea, vomiting, diarrhea (up to 49%), colitis, pruritus ani, pseudomembranous colitis (up to 14%), and metallic taste in mouth (4%).
A 19-year-old male patient, who had received 2 previous intramuscular injections of lincomycin (the active ingredient contained in Bactramycin) at the age of 17 years and 1 intramuscular injection 2 weeks prior, reported that a few minutes after his fourth intramuscular injection of lincomycin he noticed a tingling sensation around his face and mouth. The patient's symptoms progressed to bright red to blue-violet skin discoloration, injection of the bulbar conjunctivae, and swelling of his face, neck, and ears. The patient recovered without incident after receiving adrenaline and betamethasone intramuscularly followed by oral prednisone with an antihistamine.
Hypersensitivity reactions have included angioneurotic edema, serum sickness, and anaphylaxis, with rare instances of erythema multiforme, some resembling Stevens-Johnson syndrome. At least one case of face, ears, and neck swelling and bulbar conjunctival injection have been reported.
Hematologic side effects have included neutropenia, leukopenia, agranulocytosis, thrombocytopenia, and thrombocytopenic purpura. There have been rare reports of aplastic anemia and pancytopenia; however, causality could not be determined.
Dermatologic side effects have included skin rashes, urticaria, and rarely, exfoliative and vesiculobullous dermatitis.
Hepatic side effects have included jaundice and abnormalities in liver function tests; however, causality could not be determined.
Renal side effects have included rare instances of azotemia, oliguria, and proteinuria.
Cardiovascular side effects have included rare cases of cardiopulmonary arrest and hypotension after lincomycin (the active ingredient contained in Bactramycin) was administered intravenously too rapidly. In these cases, the affected patients subsequently tolerated slow infusions of lincomycin. A study that looked at multiple large dose administration of lincomycin found that when the doses were appropriately diluted and administered more slowly, cardiovascular changes did not occur.
Nervous system side effects have included neuromuscular blockade.
Genitourinary side effects have included vaginitis.
Local side effects have included infrequent reports of pain following intramuscular administration.
Other side effects have included tinnitus and vertigo.
More Bactramycin resources
- Bactramycin Concise Consumer Information (Cerner Multum)
- Lincomycin Professional Patient Advice (Wolters Kluwer)
- Lincomycin Prescribing Information (FDA)
- Lincocin Prescribing Information (FDA)
- Lincocin MedFacts Consumer Leaflet (Wolters Kluwer)
- Lincocin Monograph (AHFS DI)
- Lincocin Advanced Consumer (Micromedex) - Includes Dosage Information
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