Amphetamine Side Effects

Please note - some side effects for Amphetamine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Amphetamine - for the Consumer

Amphetamine/Dextroamphetamine

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Amphetamine/Dextroamphetamine:

Constipation; diarrhea; difficulty sleeping; dizziness; dry mouth; headache; loss of appetite; nausea; nervousness; restlessness; stomach pain or upset; unpleasant taste; vomiting; weight loss.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; change in sexual ability or desire; chest pain; confusion; depression; fast or irregular heartbeat; fever; growth suppression; mental/mood changes; numbness or tingling in an arm or leg; one-sided weakness; painful or frequent urination; seizures; severe headache; severe stomach pain; severe weight loss; sudden severe dizziness, fainting, or vomiting; uncontrolled muscle movement; unusual weakness or tiredness; vision or speech changes.

Amphetamine/Dextroamphetamine Extended-Release Capsules

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Amphetamine/Dextroamphetamine Extended-Release Capsules:

Constipation; diarrhea; difficulty sleeping; dizziness; dry mouth; headache; loss of appetite; nausea; nervousness; restlessness; stomach pain or upset; unpleasant taste; vomiting; weight loss.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision; change in sexual ability or desire; chest pain; confusion; depression; fast or irregular heartbeat; fever; growth suppression; mental/mood changes; numbness or tingling in an arm or leg; one-sided weakness; painful or frequent urination; seizures; severe headache; severe stomach pain; severe weight loss; sudden severe dizziness, fainting, or vomiting; uncontrolled muscle movement; unusual weakness or tiredness; vision or speech changes.

Side Effects by Body System

Cardiovascular

Cardiovascular side effects have included tachycardia, palpitations, and elevated blood pressure. Cardiomyopathy and myocardial infarction have been reported rarely.

Nervous system

Nervous system side effects have included depression, seizures, stroke, overstimulation, restlessness, dizziness, insomnia, euphoria, dyskinesia, dysphoria, tremor, headache, exacerbation of motor and phonic tics, and Tourette's syndrome. Psychotic episodes at recommended doses have been reported rarely.

Gastrointestinal

Gastrointestinal side effects have included dry mouth, unpleasant taste, diarrhea, constipation, anorexia, weight loss, and other disturbances.

Dermatologic

Dermatologic side effects have included urticaria.

Endocrine

Endocrine side effects have included impotence and changes in libido.

Other

Other side effects have included a significant elevation (highest in the evening) of the plasma corticosteroid levels. Amphetamines may interfere with urinary steroid determination.

General

General side effects including headache (26%) and asthenia (6%) have been reported.

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