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Thiazide diuretics

What are Thiazide diuretics?

Thiazide diuretics are a type of diuretic (a drug that increases urine flow). They act directly on the kidneys and promote diuresis (urine flow) by inhibiting the sodium/chloride cotransporter located in the distal convoluted tubule of a nephron (the functional unit of a kidney). Thiazides decrease sodium reabsorption which increases fluid loss in urine, which in turn decreases extracellular fluid and plasma volume. This reduces cardiac output (how hard the heart has to work to pump blood around the body) and lowers blood pressure. Thiazides also work in other ways to lower blood pressure. Thiazides also cause potassium loss while retaining calcium.

Thiazides are usually used for their blood pressure lowering effects because their diuretic activity is relatively weak compared to some other types of diuretic (such as loop diuretics).

List of Thiazide diuretics

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Zaroxolyn (Pro)
Generic name: metolazone
8.0
3 reviews
Microzide (Pro)
Generic name: hydrochlorothiazide
7.3
3 reviews
Thalitone (Pro)
Generic name: chlorthalidone
No reviews
Mykrox
Generic name: metolazone
No reviews
Lozol (Pro)
Generic name: indapamide
No reviews
Esidrix
Generic name: hydrochlorothiazide
No reviews
Enduron
Generic name: methyclothiazide
No reviews
Diuril Sodium
Generic name: chlorothiazide
No reviews
Diuril (Pro)
Generic name: chlorothiazide
No reviews
Aquazide H
Generic name: hydrochlorothiazide
No reviews
Aquatensen
Generic name: methyclothiazide
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See also

Medical conditions treated or associated with thiazide diuretics:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.