A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
Thiazide diuretics decrease active re-absorption of sodium and chloride ions by inhibiting the sodium/chloride co-transporter in the distal convoluted tubule. They also increase potassium ion loss. Thiazide diuretics decrease the blood volume by diuresis and are used in the treatment of hypertension.
Medical conditions associated with thiazide diuretics: