Tetanus Toxoid-Concentrated

Company: Professional Biological

Tetanus Toxoid, Concentrated

U.S. Vet. Lic. No.: 188

Active Ingredient(s): Prepared by detoxifying tetanus toxin with formaldehyde solution in such a manner as to allow the antigenic properties to remain intact. Product is purified and concentrated to provide a low dose effective immunizing agent. Each serial is tested for purity, safety and potency in accordance with applicable Standard Requirements issued by the United States Department of Agriculture.

Contains thimerosal as a preservative.

Indication(s): For the vaccination of healthy horses, cattle, sheep, goats and swine against tetanus.

Dosage and Administration

For primary immunization two doses should be administered subcutaneously or intramuscularly approximately 30 days apart. Use intramuscularly for horses as local reactions are more likely to occur if injected subcutaneously.

Horses or Cattle: 1 mL dose

Sheep, Goats, Swine: 0.5 mL dose

Annually, a single “Booster” vaccination is recommended.

Precaution(s): Shake well before using.

Use entire contents when first opened.

Store in the dark at 2 to 7°C.

Caution(s): A transitory local reaction may occur at injection site.

Anaphylactoid reaction sometimes follows administration of products of this nature. If noted, administer adrenalin or equivalent.

Warning(s): Do not vaccinate animals intended for food within 21 days before slaughter.

For veterinary use only.

Discussion: Tetanus is caused by a toxin (poison) produced by growth of Clostridium tetani, an anaerobic (lives without air) microorganism that may be carried into wounds or sites of surgical operations.

Affected animals become stiff, have great difficulty swallowing and the pulse rate is increased. Breathing is labored. Spasmodic contractions of the muscular system occur, extending muscles of the jaw. Thus the term “lockjaw” is frequently applied. Legs are often spread, tail stiff with abnormal muscles retracted. Tetanus stricken animals may be unusually sensitive to light and heat. Temperature of the animal generally remains normal, elevating only shortly before death.

Vaccination with tetanus toxoid is recommended for healthy domestic animals, not infected with tetanus, to establish an active immunity for prevention against tetanus. Protective antibody levels usually occur about two weeks after the second injection of the primary immunization series. In contrast, administration of Tetanus Antitoxin is recommended for immediate, emergency, passive treatment of exposed animals with an unknown vaccination history or with signs of tetanus infection. Refer to the product circular for Tetanus Antitoxin for full information.

Presentation: Available in single dose size packaged 10 vials to the carton and in 10 dose vials.

NAC No.: 14250040