Tetanus Toxoid-Concentrated

Manufacturer: Colorado Serum

Tetanus Toxoid

U.S. Vet. Lic. No.: 188

Active Ingredient(s): Prepared by detoxifying tetanus toxin with a formaldehyde solution and moderate heat in such a manner that the antigenic properties remain intact.

The product is refined to remove most of the nonspecific components and concentrated to provide a low dose effective immunizing agent.

Each serial is tested for purity, safety, and potency in accordance with the applicable standard requirements issued by the United States Department of Agriculture.

Contains thimerosal as a preservative.

Tetanus Toxoid-Concentrated Indications

For the vaccination of cattle, horses, sheep, goats and swine against tetanus.

Dosage and Administration

The toxoid requires three (3) to four (4) weeks to establish an effective level of protection and should be used only in non-emergency instances. Booster injections should be made annually or at the time of injury regardless of interval.

Inject intramuscularly as follows:

For horses and cattle, at least two (2) doses of 1 mL each.

For sheep, goats and swine, two (2) doses of 0.5 mL each. The interval between doses should be approximately 30 days. Revaccinate all animals retained for breeding and those held beyond the normal marketing period annually. Use the full dose as recommended above.

Precaution(s): Shake well before using. Store in the dark at 2-7°C.

Sterilize syringes and needles by boiling in clean water.

Caution(s): Transitory local reaction may appear at the site of administration.

Anaphylaxis (shock) may sometimes follow the use of products of this nature. Epinephrine, or an equivalent drug, should be available for immediate use in these instances.

Use the entire contents when first opened. For veterinary use only.

Warning(s): Do not vaccinate within 21 days before slaughter.

Discussion: Tetanus is caused by a toxin (poison) produced by the growth of Clostridium tetani, an anaerobic (lives without air) micro-organism that may be carried into the wounds or sites of surgical operations.

Affected animals become stiff, have great difficulty swallowing and the pulse rate is increased. Breathing is labored. Spasmodic contractions of the muscle system occurs, extending muscles of the jaw. Thus, the term lockjaw is frequently applied. Legs are often spread, the tail is stiff with the abdominal muscles retracted. Tetanus stricken animals may be unusually sensitive to light and heat. The temperature of the animal generally remains normal, elevating only shortly before death.

Presentation: 10 x 1 dose (10 x 1 mL) and 10 dose (10 mL) vials.

NAC No.: 11010330