SMZ-Med 454

Company: Bimeda

(sodium sulfamethazine)

Soluble Powder

FOR USE IN CATTLE, BEEF CATTLE, SWINE, CHICKENS, TURKEYS

Antibacterial

FOR ANIMAL USE ONLY

KEEP OUT OF REACH OF CHILDREN

CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.

Restricted Drug (California) - Use Only as Directed

ANADA 200-434 Approved by FDA

CONVENIENT, ONCE-A-DAY DOSAGE IN DRINKING WATER OR AS A DRENCH

Prepare Fresh Solutions Daily

Contents 100% sodium sulfamethazine

Store at 20°C - 25°C (68°F - 77°F), with excursions permitted to 15°C - 30°C (59°F - 86°F).

SMZ-Med 454 Indications

For the control and treatment of the following diseases when caused by one or more of the following pathogenic organisms susceptible to sulfamethazine.

FOR THE TREATMENT OF:

CATTLE - Bacterial Pneumonia and Bovine Respiratory Disease Complex (Shipping Fever Complex) (Pasteurella spp.); Colibacillosis (Bacterial Scours) (Escherichia coli); Necrotic Pododermatitis (Foot Rot) (Fusobacterium necrophorum); Calf Diphtheria (Fusobacterium necrophorum); Acute Metritis (Streptococcus spp.)

BEEF CATTLE - Acute Mastitis (Streptococcus spp.)

SWINE - Porcine Colibacillosis (Bacterial Scours) (Escherichia coli); Bacterial Pneumonia (Pasteurella spp.)

FOR THE CONTROL OF:

CHICKENS - Infectious Coryza (Avibacterium paragallinarum); Coccidiosis (Eimeria tenella, Eimeria necatrix); Acute Fowl Cholera (Pasteurella multocida); Pullorum Disease (Salmonella Pullorum)

TURKEYS - Coccidiosis (Eimeria meleagrimitis, Eimeria adenoeides)

Administration In Drinking Water

Prepare a 12.0% stock solution by adding the contents of this package to one gallon of water.

Dosage: Cattle, Calves And Swine

1st day: 6 tablespoons (3 fl oz) for each 100 lb body weight, providing approximately 108 mg/lb (237.6 mg/kg) body weight.

2nd, 3rd, 4th days: 3 tablespoons (1 1/2 fl oz) for each 100 lb body weight, providing approximately 54 mg/lb (118.8 mg/kg) body weight.

DOSAGE: POULTRY: Add 2 tablespoons (1 fl oz) to each gallon, or one gallon of stock solution to 128 gallons. Following administration directions, this will provide a recommended dose of approximately 58 to 85 mg/lb/day (128 to 187 mg/kg/day) body weight in chickens and 50 to 124 mg/lb/day (110 to 273 mg/kg/day) body weight in turkeys, depending upon the dosage, age, class of chickens or turkeys, ambient temperature and other factors.

Precautions

Have only medicated water available during treatment, and check carefully to insure adequate drug dosage and water intake. Cattle and calves not drinking or eating must be dosed by drench or with immediate release sulfamethazine bolus. For best results, treat sick animals individually. For control of outbreaks of disease, medication should be initiated as soon as the diagnosis is determined. Medicated cattle, swine, chickens and turkeys must actually consume enough medicated water which provides the recommended dosages. SMZ-Med 454 works fast. If symptoms persist after using this preparation for 2 or 3 days, consult a veterinarian. Excessive dosage may cause toxic reactions. Follow dosage and administration instructions carefully. Hatchability of eggs laid during medication with sulfas, and for short periods thereafter, may be adversely affected. Treatment of all diseases should be instituted early. Treatment should continue 24 to 48 hours beyond the remission of disease symptoms, but not to exceed a total of 5 consecutive days in cattle or swine.

ADMINISTRATION:

CATTLE, CALVES, AND SWINE:

In Drinking Water: Add the required dose listed above to that amount of water that will be consumed in one day; consumption should be carefully checked. Factors such as temperature, humidity, and disease will cause variable fluid intake. As a generalization, the animals listed above will consume approximately 1 gallon per 100 lb body weight per day.

As a Drench: Dilute the proper dose of stock solution, and drench or administer with dose syringe.

Cattle and calves not drinking must be dosed by drench or with immediate release sulfamethazine bolus. For best results, pen-up animals to be treated, and treat sick animals individually.

CHICKENS AND TURKEYS:

Add the required dose to that amount of water that will be consumed in one day. Water consumption should be carefully checked to insure adequate drug intake. As a generalization, 100 turkeys will drink one gallon of water per day for each week of age; chickens will consume one-half this amount.

INFECTIOUS CORYZA (in chickens): Medicate for 2 consecutive days.

ACUTE FOWL CHOLERA AND PULLORUM DISEASE (in chickens): Medicate for 6 consecutive days.

COCCIDIOSIS (in chickens and turkeys): Medicate as above for 2 days, then reduce drug concentration to one-half above for 4 additional days.

SMZ-Med^® is a Registered Trademark of Bimeda, Inc.

N.A. Corp. Address: Bimeda, Inc., One Tower Lane, Oakbrook Terrace, IL 60181

Manufactured by: Bimeda, Inc., Le Sueur, MN 56058

www.bimeda.com

MADE IN USA

CPN: 1399087.5