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This page contains information on Neomycin for veterinary use.
The information provided typically includes the following:
  • Neomycin Indications
  • Warnings and cautions for Neomycin
  • Direction and dosage information for Neomycin


This treatment applies to the following species:
Company: VetOne

(Neomycin Sulfate)






Neomycin Caution

Federal law restricts this drug to use by or on the order of a licensed veterinarian.

ANADA 200-289, Approved by FDA

Restricted Drug (California) - Use Only as Directed

Not for Human use.

Neomycin Indications

For the treatment and control of colibacillosis (bacterial enteritis) caused by Escherichia coli susceptible to neomycin sulfate in cattle (excluding veal calves), swine, sheep and goats.

For the control of mortality associated with Escherichia coli organisms susceptible to neomycin sulfate in growing turkeys.

Dosage and Administration

Administer to cattle (excluding veal calves), swine, sheep and goats at a dose of 10 mg neomycin sulfate per pound of body weight in divided doses for a maximum of 14 days. Administer to turkeys at a dose of 10 mg neomycin sulfate per pound of body weight per day for 5 days.

Pounds of Body Weight

Amount of Neomycin Solution Per Day in Divided Doses

25 lbs

1.2 mL (1/4 teaspoonful)

50 lbs

2.5 mL (1/2 teaspoonful)

100 lbs

5.0 mL (1 teaspoonful)

300 lbs

15 mL (1 tablespoonful)

591.5 lbs

29.5 mL (1 fluid ounce)

Teaspoon = U.S. Standard Measure

Neomycin Solution may be given undiluted or diluted with water.

HERD TREATMENT: Each 473 mL (1 pt.) will treat 9464 pounds of body weight. Each 3.785 L (1 gallon) will treat 75,700 pounds of body weight. Therefore, estimate the total number of pounds of body weight of animals to be treated and administer 29.5 mL (1 fl. oz.) for each 591.5 lbs. The product should be added to the amount of drinking water estimated to be consumed in 12-24 hours. Provide medicated water as the sole source of water each day until consumed, followed by non-medicated water as required. Fresh medicated water should be prepared each day.

INDIVIDUAL ANIMAL TREATMENT: To provide 10 mg neomycin sulfate per pound of body weight, mix 5 mL (1 tsp) in water or milk for each 100 lbs of body weight. Administer daily either as a drench in divided dosages or in the drinking water to be consumed in 12-24 hours.


Each mL contains 200 mg of neomycin sulfate equivalent to 140 mg neomycin base.


To administer the stated dosage, the concentration of neomycin required in medicated water must be adjusted to compensate for variation in age and weight of animal, the nature and severity of disease signs, and environmental temperature and humidity, each of which affects water consumption.

If symptoms persist after using this preparation for 2 or 3 days, consult a veterinarian. If symptoms such as fever, depression or going off feed develop, oral neomycin is not indicated as the sole treatment since systemic levels of neomycin are not obtained due to poor absorption from the gastrointestinal tract.

IMPORTANT: Treatment should continue 24 to 48 hours beyond remission of disease symptoms, but not to exceed a total of 14 consecutive days. Animals not drinking or eating should be treated individually by drench.

RESIDUE WARNINGS: Discontinue treatment prior to slaughter as follows:

Turkeys - 0 day; Cattle - 1 day; Sheep - 2 days; Swine and Goats - 3 days

A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal. A milk discard period has not been established for this product in lactating dairy cattle. Do not use in female dairy cattle 20 months of age or older.

Use of more than one product containing neomycin or failure to follow withdrawal times may result in illegal drug residues.

Store at Controlled Room Temperature 15° to 30° C (59° to 86° F).

Distributed by: MWI, Boise, ID 83705

Net Contents:




1 Pint (473 mL)


V1 510570

Rev. 12/16

1 Gallon (3.785 L)


V1 510571

Rev. 12/16

CPN: 1315194.1

Distributed by MWI Animal Health

3041 W. PASADENA DR., BOISE, ID, 83705
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