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LS Mass II

This page contains information on LS Mass II for veterinary use.
The information provided typically includes the following:
  • LS Mass II Indications
  • Warnings and cautions for LS Mass II
  • Direction and dosage information for LS Mass II

LS Mass II

This treatment applies to the following species:
Company: Zoetis

Newcastle-Bronchitis Vaccine

B1 Type, LaSota Strain, Mass. Type, Live Virus

For veterinary use only

Read in full, follow directions carefully.

Store at 2°-8°C. Prolonged exposure to higher temperatures and/or direct sunlight may adversely affect potency. Do not freeze.

Use entire contents when first opened.

Inactivate unused contents before disposal.

Do not vaccinate within 21 days before slaughter.

Contains gentamicin as a preservative.

Do not mix with other products, except as specified on the label.

In case of human exposure, contact a physician.

This product has been shown to be effective for the vaccination of healthy chickens 2 weeks of age and older against Newcastle disease and infectious bronchitis virus, Massachusetts type. Duration of immunity has not been established. For more information regarding efficacy and safety data, go to

LS Mass II is a combination live-virus vaccine. The Newcastle fraction is the B1 type, LaSota strain, and the bronchitis fraction is prepared from a modified strain of infectious-bronchitis virus, Massachusetts type.


For Drinking-water Vaccination

LS Mass II Newcastle-Bronchitis Vaccine is recommended for the vaccination of healthy chickens 2 weeks of age or older.

1. Discontinue use of medications or sanitizing agents in the drinking water 24 hours before vaccinating. Do not resume use for 24 hours following vaccination.

2. Water used for the drinking-water administration of alive virus vaccine must be non-chlorinated.

3. Provide enough waterers so two-thirds of the birds may drink at one time. Scrub waterers with fresh, clean, non-chlorinated water, and use no disinfectant.Let the waterers drain dry.

4. Turn off automatic waterers, so the only available water is the vaccine water. Do not give vaccine water through medication tanks.

5. Withhold water for 2 to 4 hours before vaccinating. Do not deprive the birds of water if the temperature is extremely high.

6. Remove seal from vaccine vial.

7. Remove stopper and half-fill vial with clean, cool, non-chlorinated water.

8. Replace stopper and shake until dissolved.

9. Use a clean container two-thirds filled with cool, clean, non-chlorinated water. Add dried milk at a rate of 10 ounces (284 grams) per 25 gallons (95 liters) of the final volume of vaccine solution. Stir the mixture until the dried milk is dissolved.

10. Add the rehydrated vaccine from the vial and again stir the contents thoroughly.

11. Next, add the mixture to the final volume of water, as follows:

Add this amount of vaccine

to this final volume of water

for chickens 2 to 8 weeks old

for chickens over 8 weeks old

10,000 doses

25 to 50 gallons (95 to 190 liters)

50 to 100 gallons (190 to 380 liters)

12. Give 1 dose of vaccine per bird.

13. Distribute the final volume of (vaccine) water evenly among the clean waterers. Do not place the waterers in direct sunlight. Resume regular water administration only after all the vaccine water has been consumed.


If possible, vaccinate all susceptible birds on the premises at the same time. For 10 to 14 days after vaccinating, avoid carrying vaccine particles on shoes, clothing, etc., into areas where there are unvaccinated birds.

Newcastle Disease Vaccine virus is capable of causing a mild, irritating eye infection in humans, lasting about 3 days. Do not allow vaccine to contact the eyes.

LS Mass II Caution

This product should be stored, transported, and administered in accordance with the instructions and directions.

The use of this vaccine is subject to state laws, wherever applicable.


Keep a record of vaccine serial number and expiration date; date of receipt and date of vaccination; where vaccination takes place; and any reactions observed.


Technical inquiries should be directed to Zoetis Inc. Veterinary Services, (888) 963-8471

VLN 190/PCN 1771.12

Zoetis Inc., Kalamazoo, MI 49007


CPN: 3690290.3

Telephone:   269-359-4414
Customer Service:   888-963-8471
THIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.

Copyright © 2023 Animalytix LLC. Updated: 2023-05-30