Skip to main content

Gen-Gard Soluble Powder

This page contains information on Gen-Gard Soluble Powder for veterinary use.
The information provided typically includes the following:
  • Gen-Gard Soluble Powder Indications
  • Warnings and cautions for Gen-Gard Soluble Powder
  • Direction and dosage information for Gen-Gard Soluble Powder

Gen-Gard Soluble Powder

This treatment applies to the following species:
Company: Huvepharma

(gentamicin sulfate)


CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.

For Swine Drinking Water Only.


Each gram of GEN-GARD Soluble Powder contains gentamicin sulfate equivalent to 333.33 mg gentamicin base.

RESIDUE WARNING: Swine treated with the recommended dose of GEN-GARD Soluble Powder must not be slaughtered for food for at least ten (10) days following the last treatment.

Gen-Gard Soluble Powder Indications

GEN-GARD Soluble Powder is recommended for the control and treatment of colibacillosis in weanling swine caused by strains of E. coli sensitive to gentamicin and for the control and treatment of swine dysentery associated with Brachyspira hyodysenteriae.

Dosage and Administration

GEN-GARD Soluble Powder is available in a 360 gram jar. The 360 gram jar contains a scoop that provides approximately 18 grams of product when level full.

For Control and Treatment of Colibacillosis - Administer GEN-GARD Soluble Powder in drinking water at the recommended level of 25 mg per gallon (1 scoop/240 gallons) for three consecutive days.

For Control and Treatment of Swine Dysentery - Administer GEN-GARD Soluble Powder in drinking water at the recommended level of 50 mg per gallon (1 scoop/120 gallons) for three consecutive days.

The concentration of the medication should be adjusted in extremely hot or cold weather to ensure a gentamicin dosage of approximately 0.5 mg/lb/day for 3 days for colibacillosis or 1.0 mg/lb/day for 3 days for swine dysentery. A 50-lb pig will, under average conditions, consume 0.9 gallon of water per day.

For swine dysentery, if the condition recurs, the medication may be repeated. Because of the tendency for the disease to recur on a premise with a history of swine dysentery, a control program should be used following treatment.

Directions For Use

To prepare medicated water, mix GEN-GARD Soluble Powder and drinking water according to the following tables:

Proportioner Use:

For Control and Treatment of Colibacillosis

Add 18 g (1 scoop) GEN-GARD to 2 gallons of water to make stock solution and dispense at the rate of one ounce per gallon of drinking water. This will result in drinking water that contains 25 mg/gallon.

Bulk Preparation:

For Control and Treatment of Colibacillosis

Add 18 g (1 scoop) GEN-GARD to 240 gallons of water.

For Control and Treatment of Swine Dysentery

Add 18 g (1 scoop) GEN-GARD to 120 gallons of water.

Medicated drinking water should not be stored or offered in rusty containers since the drug is quickly destroyed in such containers.

Medicated water should be prepared daily and be the sole source of drinking water for 3 consecutive days.

The daily water consumption figures shown below are approximations for mild temperatures and are presented as a guide only. Actual water consumption varies with environmental temperature, humidity, and diet.

Approximate Daily Water Consumption

Weight of Pig (lb)

Gallons for 5 Pigs

Gallons for 10 Pigs













Side Effects

There have been no reported side effects following the recommended use of GEN-GARD Soluble Powder in swine.

To report suspected adverse drug events, for technical assistance or to obtain a copy of the Safety Data Sheet (SDS), contact Huvepharma, Inc. at 1-877-994-4883 or For additional information about adverse drug experience reporting for animal drugs, contact FDA at 1-888-FDA-VETS or


There are no known contraindications to this drug when used as directed.

STORAGE CONDITIONS: Store between 2° and 30°C (36° and 86°F)

How Supplied

GEN-GARD Soluble Powder is available in a 360 gram jar with 2 jars per shipper.

Approved by FDA under ANADA # 200-185

Not for Use in Humans

Keep Out of Reach of Children

Restricted Drug (California) - use only as directed

®Registered trademark of Huvepharma, Inc.

Manufactured for

Huvepharma, Inc., Peachtree City, GA 30269




360 g (12.7 oz.)
Contains 120 grams of Gentamicin per jar


G-7473-03 Rev. 04-2022

CPN: 1309079.0

Telephone:   770-486-7212
Toll-Free:   877-994-4883
Fax:   770-486-7217
THIS SERVICE AND DATA ARE PROVIDED "AS IS". DVMetrics assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics service and data. See the Terms of Use for further details.

Copyright © 2023 Animalytix LLC. Updated: 2023-05-29