Furazone Dressing (Canada)

Company: Wecan Sales

Nitrofurazone ointment, Mfr. Std.

Veterinary Use Only

TOPICAL ANTIBACTERIAL

DIN 02311917

GENERAL INFORMATION: Nitrofurazone is a synthetic nitrofuran with a broad antibacterial spectrum. It effectively destroys most bacteria commonly causing surface infections, including many that have become antibiotic-resistant.

It acts by inhibiting enzymes necessary for carbohydrate metabolism in bacteria. This action occurs in both the aerobic and anaerobic cycles of carbohydrate metabolism, explaining its bactericidal effect in aerobic, anaerobic and anaerobic facultative bacteria. For best effect it should be applied for at least 24 hours. It retains its antibacterial activity in blood, serum and pus, phagocytosis is not inhibited nor does it interfere with healing.

Five to seven days of topical therapy will eradicate most infections. If desired, any bland agent or protective dressing can be used for the remainder of the healing period. Therapy can be repeated if the infection reoccurs.

Warning

FEDERAL LAW PROHIBITS THE ADMINISTRATION OF THIS PREPARATION TO ANIMALS THAT PRODUCE FOOD OR THAT ARE INTENDED FOR CONSUMPTION AS FOOD. Keep out of reach of children. This drug is not to be used on horses that are to be slaughtered for use in food.

SENSITIZATION: The incidence of irritation or sensitization has been low. This incidence is approximately 2%, including irritation and sensitivity incurred in treating chronic stasis ulcers, notoriously easily irritated by any agent. In surgical cases, as in burns, irritation and sensitivity are seldom seen, the incidence not exceeding 1%.

To minimize any adverse effect, the veterinarian should remove the medication by irrigation at the first sign of irritation. It may be helpful, in chronic stasis ulcers, to protect the easily irritated skin surrounding them with zinc oxide ointment, and to confine the drug to the lesion itself.

FURAZONE DRESSING does not, of course, replace surgical procedures when these are indicated, however it is a useful adjunct.

Active Ingredient

FURAZONE DRESSING contains 0.2% w/w nitrofurazone dissolved in a water-soluble base of polyethylene glycols.

Furazone Dressing Indications

FURAZONE DRESSING is an antibacterial ointment indicated as an aid in the prophylaxis and treatment of superficial bacterial infections, sensitive to nitrofurazone, associated with wounds, burns, cutaneous ulcers, skin grafts and donor sites and for the treatment of pyodermas in dogs and horses.

Directions For Use

Wounds and burns: Apply directly to the lesion as with a spatula, or first place on gauze. Impregnated gauze may be used. Reapply once daily or once weekly, depending on the preferred dressing technique. To avoid adherence by drying of exudates, impregnated gauze may be covered by waxed paper or petroleum gauze.

Pyodermas: Apply several times daily with or without a gauze dressing. Use only on abscesses and furuncles following incision or rupture.

Ulcers: Varicose and decubitus ulcers may be treated as are wounds and burns. However, in chronic cases, it is advisable to protect the abnormally sensitive skin about the lesion with zinc oxide ointment or paste. Restricting application to five to seven days where feasible, minimizes irritation and sensitization. It is effective only when bacterial infection is responsible for lack of healing.

Skin grafts: The dressing is used both to prepare burns and other lesions for grafting, and postoperatively as a prophylactic measure. By rapid eradication of the infection, it can produce clean, firm granulation tissue. Because it is water-soluble and has negligible tissue toxicity, it does not interfere with successful takes. To avoid adherence on the bandage, FURAZONE DRESSING impregnated gauze may be covered by waxed paper or petroleum gauze. This may be left intact for 5 to 7 days. Flushing the gauze with saline facilitates removal.

Furazone Dressing Caution

In case of deep or puncture wounds or serious burns, consult a veterinarian. If redness, irritation or swelling persists or increases, discontinue use and consult a veterinarian.

STORAGE CONDITIONS: Store between 15 and 30°C. Avoid freezing. The discoloration of these preparations by light does not indicate loss of efficacy.

NET CONTENTS: 454g / 2 Kg

Manufactured By: Wecan Sales, 3768 Mountain Rd., Beamsville, ON LOR 1B0

905-563-0808

CPN: 1736001.0