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Fatal-Plus Powder

This page contains information on Fatal-Plus Powder for veterinary use.
The information provided typically includes the following:
  • Fatal-Plus Powder Indications
  • Warnings and cautions for Fatal-Plus Powder
  • Direction and dosage information for Fatal-Plus Powder

Fatal-Plus Powder

This treatment applies to the following species:
Company: Vortech

For Animals of All Species


For fast and humane euthanasia FATAL-PLUS contains pentobarbital sodium as the active ingredient. Solution is dyed blue and labeled for easy identification or isolation. All vials are silk screen labeled to prevent smudging or peeling.

Each ml. contains:

Pentobarbital sodium

392 mg/ml.


Produces classic euthanasia by sequentially depressing the cerebral cortex, the lungs and the heart. Action on target organs gives humane euthanasia of unparalleled speed, effectiveness and specificity. Instant unconsciousness is induced with simultaneous collapse of the animal. Deep pentobarbital anesthesia ensues with blood pressure fall, stoppage of breathing and cerebral death. Cardiac function stops, quickly and irreversibly.

Fatal-Plus Powder Indications:

For fast and humane euthanasia of all animals regardless of species.

Directions for Mixing: Slowly add water (150 ml. to 200 ml.). Replace cap and shake well until powder is dissolved. Add more water to the 250 ml. mark only. Do not exceed the fill line (250 ml.).

Dosage and Administration

Intravenous injection is the preferred route. However, intraperitoneal or intracardiac injections may be made where the intravenous injection is impractical, as in the very small dog and cat, or in the comatose animal with depressed vascular function. Inject rapidly 1 ml. for every 10 lbs body weight. Minimum 1 ml. The use of tranquilizers is recommended for IP or IC injections.


Euthanasia may sometimes be delayed in animals with severe cardiac or circulatory deficiencies. This may be explained by the impaired movement of the drug to the site of action. When restraint may cause the animal pain, injury or anxiety, or cause danger to the person making the injection, prior use of tranquilizing drugs may be necessary.

Fatal-Plus Powder Caution:

Caution should be exercised to avoid contact of the drug with open wounds or accidental self-inflicted injections. In case of occurrence wash the contact area thoroughly with soap and water. Keep out of reach of children. For additional information consult the FATAL-PLUS M.S.D.S.


For euthanasia only. Must not be used for therapeutic purposes. Do not use in animals intended for food.

ENVIRONMENTAL HAZARD: This product is toxic to wildlife. Birds and mammals feeding on treated animals may be killed. Euthanized animals must be properly disposed of by deep burial, incineration, or other method in compliance with state and local laws, to prevent consumption of carcass material by scavenging wildlife.

How Supplied

250 ml. multiple dose screw cap vial, packed 12 vials per case. DEA Form No. 222 required to purchase.


Product No.

N.D.C. No.


V.P.L. 9372



Fatal-Plus Powder Caution:

Federal (USA) law restricts this drug for use by or on the order of a licensed veterinarian.

Once constituted, potency is guaranteed for 35 days.


CPN: 10980002

Telephone:   313-584-4088
Order Desk:   800-521-4686
Fax:   313-581-8550
Toll-Free (Inside Michigan):   800-372-2714
Toll-Free (Other States & Canada):   800-521-4686
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Copyright © 2023 Animalytix LLC. Updated: 2023-05-30