Chorulon (Canada)
This treatment applies to the following species:CHORIONIC GONADOTROPHIN FOR INJECTION, Mfr. Std. 5,000 IU or 10,000 IU
FOR VETERINARY USE ONLY
DIN 00781851
DESCRIPTION
Chorulon is presented as a white freeze-dried crystalline cake containing 5,000 IU or 10,000 IU of chorionic gonadotrophin. It is supplied with a vial of sterile diluent for reconstitution. Concentration after reconstitution is 1,000 IU per 1 mL.
THERAPEUTIC CLASSIFICATION
Chorulon (Human chorionic gonadotrophin) is a complex glycoprotein capable of supplementing and being substituted for the luteinizing hormone secreted by the anterior pituitary gland in both the maturation of the follicle, ovulation and the formation of the corpus luteum. In the male Chorulon stimulates the interstitium to the production of testosterone and thus influences the development and maintenance of primary and secondary male sex characteristics. These properties make Chorulon suitable for the treatment of several fertility problems in domestic animals due to deficiencies of natural luteinizing hormone (LH) or interstitial cell stimulating hormone (ICSH).
INDICATIONS
As an aid in the treatment of the following fertility problems in cows and heifers:
cystic ovary syndrome: anoestrus, prolonged oestrus and/or nymphomania due to cystic ovaries.
RECONSTITUTION
Using a sterile syringe and a sterile hypodermic needle, transfer 5 mL (5,000 IU) or 10 mL (10,000 IU) of diluent into the vial containing the preparation. Shake thoroughly until the suspension is uniform after which the injection may be given. After reconstitution, the solution should be used immediately or within 24 hours. Refrigeration after reconstitution is recommended.
DOSAGE AND ADMINISTRATION
Chorulon must be reconstituted with Chorulon Sterile Diluent before use.
Animal species |
Chorulon Indications |
|
Cow, Heifer |
Cystic ovary syndrome: anoestrus, prolonged oestrus |
2,500 IU I.V. (2.5 mL) |
and/or nymphomania due to cystic ovaries |
10,000 IU I.M. (10 mL) |
DURATION
Dosage may be repeated in 21 days if necessary.
CAUTIONS
In rare cases as with all protein preparations anaphylaxis may occur shortly after injection. Epinephrine HCl given intravenously or intramuscularly when symptoms appear is the standard treatment.
WARNINGS
Keep out of reach of children.
Wash hands immediately and thoroughly after applying Chorulon or wear gloves. If accidental skin contact occurs, wash the affected area immediately with soap and water. In case of accidental self-injection, seek medical attention.
STORAGE
Do not store above 25°C. Protect from light and from freezing. After reconstitution the product may be stored at 2-8°C for no longer than 24 hours.
HOW SUPPLIED
Five vials containing white freeze dried powder, and five 5 ml vials containing sterile diluent.
One vial containing white freeze dried powder, and one 10 ml vial containing sterile diluent.
INTERVET CANADA CORP., 16750, route Transcanadienne, Kirkland, QC H9H 4M7
1 888 306-0069
Intervet Canada Corp. is a subsidiary of Merck & Co., Inc.
February 13, 2012
09-0107 INS
CPN: 12081344
Intervet Canada Corp.
16750 ROUTE TRANSCANADIENNE, KIRKLAND, QC, H9H 4M7
Order Desk: | 514-428-7013 | |
Toll-Free: | 866-683-7838 | |
Fax: | Toll-free 888-498-4444; local 514-428-7014 | |
Website: | www.merck-animal-health.ca |
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