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Cefa-Lak (Canada)

This page contains information on Cefa-Lak for veterinary use.
The information provided typically includes the following:
  • Cefa-Lak Indications
  • Warnings and cautions for Cefa-Lak
  • Direction and dosage information for Cefa-Lak


This treatment applies to the following species:
Company: Boehringer

Cephapirin Sodium

Intramammary Infusion

Veterinary Use Only

DIN 02173263


Cefa-Lak (cephapirin sodium) is a cephalosporin which possesses a wide range of antimicrobial activity against gram-positive and gram-negative organisms. It is derived biosynthetically from 7-aminocephalosporanic acid.

Active Ingredient

Each 10 mL disposable syringe contains 200 mg of cephapirin activity in a stable peanut oil gel.


Do not store above 25°C. Do not freeze.

Action: Cephapirin is bactericidal to susceptible organisms; it is known to be highly active against Streptococcus agalactiae and Staphylococcus aureus including strains resistant to penicillin.

To determine the susceptibility of bacteria to cephapirin in the laboratory, the class disc, Cephalothin Susceptibility Test Discs, 30 mcg, should be used.

Cefa-Lak Indications


For the Treatment of Bovine Mastitis: Cefa-Lak for Intramammary Infusion has been shown to be efficacious in the treatment of mastitis in lactating cows caused by susceptible strains of Streptococcus agalactiae and Staphylococcus aureus including strains resistant to penicillin.

Cefa-Lak for Intramammary Infusion should be used at the first signs of inflammation or at the first indication of any alteration in the milk. Treatment is indicated immediately upon determining, by C.M.T. (California Mastitis Test) or other tests, that the leucocyte count is elevated, or that a susceptible pathogen has been cultured from the milk.

Dosage and directions for use: Infuse the entire contents of one syringe (10 mL) into each infected quarter immediately after the quarter has been completely milked out. Repeat once only in 12 hours. If definite improvement is not noted within 48 hours after treatment, the causal organism should be further investigated. Consult your veterinarian.

Milk out udder completely. Wash the udder and teats thoroughly with warm water containing a suitable dairy antiseptic and dry, preferably using individual paper towels. Carefully scrub the teat end and orifice with 70% alcohol, using a separate swab for each teat. Allow to dry.

Cefa-Lak (cephapirin sodium) is packaged with the protective cap.

For partial insertion: Twist off upper portion of the protective cap to expose 3-4 mm of the syringe tip.

For full insertion: Remove protective cap to expose the full length of the syringe tip.

Insert syringe tip into the teat canal and expel the entire contents of one syringe into each infected quarter. Withdraw the syringe and gently massage the quarter to distribute the suspension into the milk cistern. Do not milk out for 12 hours after last treatment.

Do not infuse contents of the mastitis syringe into the teat canal if the protective cap is broken or damaged.

Reinfection - The use of antibiotics, however effective, for the treatment of mastitis will not significantly reduce the incidence of this disease in the herd unless their use is fortified by good herd management, and sanitary and mechanical safety measures are practiced to prevent reinfection.

Cefa-Lak Caution

Cefa-Lak should be administered with caution to subjects which have demonstrated some form of allergy, particularly to penicillin. Such reactions are rare; however, should they occur, discontinue treatment and consult your veterinarian.


Milk taken from treated animals during treatment and within 96 hours after the latest treatment must not be used as food. Treated animals must not be slaughtered for use in food for at least 4 days after the latest treatment with this drug. Administration of more than the prescribed dose may lead to residue of antibiotic in milk for more than 96 hours. Peanut Allergy Warning: This product contains peanut oil. KEEP OUT OF REACH OF CHILDREN.

Supply: Cefa-Lak (cephapirin sodium) for Intramammary Infusion. Cephapirin sodium equivalent to 200 mg of cephapirin activity per 10 mL syringe.

Cartons containing 12 x 10 mL syringes or 24 x 10 mL syringes.

Cefa-Lak is a registered trademark of Boehringer Ingelheim Vetmedica, Inc., used under license.

Boehringer Ingelheim (Canada) Ltd., 5180 South Service Road, Burlington, Ontario L7L 5H4



CPN: 1230073.3

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