Skip to main content

Bursine Plus

This page contains information on Bursine Plus for veterinary use.
The information provided typically includes the following:
  • Bursine Plus Indications
  • Warnings and cautions for Bursine Plus
  • Direction and dosage information for Bursine Plus

Bursine Plus

This treatment applies to the following species:
Company: Zoetis

Bursal Disease Vaccine

Live Virus

For veterinary use only.

Read in full, follow directions carefully.

Store vaccine at not over 45°F (7°C).

Do not vaccinate within 21 days before slaughter.

Use entire contents of vial when first opened.

Burn vaccine container and all unused contents.

Bursine Plus Caution

Use only in states where permitted and on premises with a history of infectious bursal disease.

Contains gentamicin as a preservative.

Bursine Plus is a live virus vaccine to aid in the prevention of infectious bursal disease (IBD or Gumboro disease) of chickens.

Bursine Plus is well suited for the priming of breeder replacement pullets prior to the vaccination with an inactivated IBD vaccine.

For drinking water administration to healthy growing chickens as young as 7 days of age as an aid in the prevention of infectious bursal disease.


Chickens: Vaccinate healthy chickens via the drinking water at 7 days of age or older.

Breeders: When used as a primer for an inactivated IBD vaccine, Bursine Plus should be administered via the drinking water 6 to 8 weeks prior to administration of an inactivated product.

1. Discontinue use of medication or sanitizing agents in the drinking water 4 hours before vaccinating. Do not resume use for 24 hours following vaccination.

2. Water used for the drinking water administration of a live virus vaccine must be non-chlorinated.

3. Provide enough waterers so two-thirds of the birds may drink at one time. Scrub waterers with fresh, clean, non-chlorinated water and use no disinfectant. Let waterers drain dry.

4. Turn off automatic waterers, so the only available water is the vaccine water. Do not give vaccine water through medication tanks.

5. Withhold water for 2 to 4 hours before vaccinating. Do not deprive the birds of water if the temperature is extremely high.

6. Remove seal from vaccine vial.

7. Remove stopper and half-fill vial with clean, cool, non-chlorinated water.

8. Replace stopper and shake until dissolved.

9. Use a clean container two thirds filled with cool, clean, non-chlorinated water. Add dried milk at the rate of one ounce (28.4 gm) per 2 U.S. gallons (7.6 liters). Use 1 to 2 gallons (3.8-7.6 liters) of this solution for 1,000 doses of vaccine.

10. Add the rehydrated vaccine to the powdered milk solution and stir thoroughly.

11. Distribute the final volume of vaccine water evenly among the clean waterers. Do not place the waterers in direct sunlight. Resume regular water administration only after all the vaccine water has been consumed.

Bursine Plus Caution

This product should be stored, transported, and administered in accordance with the instructions and directions. Use only in states where permitted and on premises with a history of infectious bursal disease.


Keep a record of vaccine serial number and expiration date, date of receipt and date of vaccination, where vaccination takes place, and any reactions observed.


List No. 35753: 10 x 1,000 Doses

00964: 10 x 5,000 Doses

72111: 10 x 10,000 Doses

49119: 25,000 Doses

U.S. Vet. License No. 190

Zoetis Inc., Kalamazoo, MI 49007, USA

13861600, 13862900

CPN: 3690279.3

Telephone:   269-359-4414
Customer Service:   888-963-8471
This service and data are provided "AS IS". DVMetrics and assumes no liability, and each user assumes full risk, responsibility, and liability, related to its use of the DVMetrics and services and data. See the terms of use for further details.

Copyright © 2022 Animalytix LLC. Updated: 2021-11-29